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Biomedical subjects
Publications and source records attributed to T Rosen.
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We describe herein a patient with a verruciform xanthoma of the penis. This histologically distinctive lesion is usually confined to the oral mucosa, although two cases occurring on the vulva have recently been reported. To our knowledge, this lesion has not been previously described in other sites. Biopsy for histopathologic examination is required to aid in the identification of this unusual entity. Verruciform xanthomas have been benign, although a squamous cell carcinoma subsequently developed in one patient whose oral lesions were associated with leukoplakia.
A 63-year-old woman with numerous fibrofolliculomas on the face, neck, ears, and trunk is described. These papular lesions developed at approximately 30 years of age. Various family members have clinically identical lesions suggesting an autosomal dominant disorder. The hamartomatous lesions consisted of a proliferation of the pilar fibrous root sheath which surrounded anastomosing bands of epithelium arising from the hair follicle. The clinical and pathologic features of pilar complex tumors are reviewed.
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A case of contact dermatitis caused by ECG electrode cream is presented and the pertinent literature is reviewed. Our patient was found to be allergic to propylene glycol. Patch-testing remains an invaluable tool in the evaluation of patients suspected of being allergic to ECG paste, creams, and gels.
Ultrastructural features of the Medlar body, the tissue form of cutaneous chromomycosis, are reported. Striking variability in such features reflects the interaction between fungi and host defense mechanisms.
Successful management of keratoacanthomas and basal-cell epitheliomas by intralesional injections of 5-fluorouracil is reported.
A patient with clinical and histologic features typical of Zoon's balanitis plasmacellularis is presented herein. This entity has been infrequently reported in the English literature, perhaps due to a lack of familiarity with the disease.
A persistent papular eruption in black men characterized clinically by small, pruritic papules and histologically by a mononuclear cell-eosinophil perivascular infiltrate is described. This disorder, seen only in young black men, is not readily classifiable within existing dermatologic taxonomy.
Four subjects were exposed to dorsal spines of the Automeris io caterpillar. The experimental presented herein indicates that there is a substantial variability in response between human subjects. The urticarial reaction produced can be categorized broadly as contact urticarda and most probably is nonimmunologic, depending on mediator release.
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