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Biomedical subjects

T Rosen

Publications and source records attributed to T Rosen.

At least 145 records · Page 8Linked to original sources
PubMed1984

Subungual squamous cell carcinoma.

Subungual squamous cell carcinoma is a rare phenomenon. Diagnosis of this condition is often delayed because of a resemblance to a variety of benign inflammatory conditions. Metastases are unusual, but involvement of underlying bone is common. Curative treatment is achieved by amputation of the involved digit. The index of suspicion for malignancy in the face of an inflammatory nail condition unresponsive to standard treatment should be high, and a biopsy should be performed.

Aged↗
PubMed1984

Darkly pigmented lesions in dark-skinned patients.

It is well known that fair-haired, fair-complected individuals have an increased risk of skin malignancies. Current literature, however, gives no aid in evaluating darkly pigmented lesions in the dark-skinned patient. Blacks have an incidence of malignant melanoma from 5 to 18 times less than whites, while Hispanics have a higher incidence than blacks, but 3.5 to 4.5 times less than whites. Basal-cell epitheliomas are more likely to be darkly pigmented in both groups, leading to erroneous diagnosis and treatment as melanomas.

Adult↗
PubMed1983

African trypanosomiasis in the United States.

African trypanosomiasis of the Rhodesian variety occurred in an American who recently traveled to Tanzania. Skin findings included a fluctuant, indurated, tsetse-fly bite site (chancre) and a fleeting, erythematous, macular eruption. The diagnosis was confirmed by the presence of the organism in peripheral blood smears. The patient's condition responded to intravenous suramin. African trypanosomiasis should be included in the differential diagnosis of patients who have visited areas where this disease is endemic, and in whom the appropriate skin findings are present.

Africa↗
PubMed1983

Cutaneous mucinosis associated with thyroid dysfunction.

An unusual case of pruritic, papular cutaneous mucinosis in conjunction with hypothyroidism is described. Resolution of this disorder followed thyroid hormone supplementation. The various cutaneous mucinoses and the pathogenesis of mucin deposition are reviewed.

Adult↗
PubMed1983

Pityriasis rubra pilaris as the initial manifestation of leukemia.

The association of pityriasis rubra pilaris (PRP) with an underlying disease is unusual. A case of a PRP-like eruption presenting as the initial manifestation of acute stem cell leukemia is reported. Other noncutaneous diseases previously reported in association with PRP are reviewed. Other cutaneous lesions associated with leukemia are also briefly described.

Acute Disease↗
PubMed1983

Cutaneous Mycobacterium kansasii infection presenting as cellulitis.

An immunocompromised renal transplant patient developed a cellulitis-like lesion on the leg. This lesion and subsequent periarticular lesions proved to be due to Mycobacterium kansasii. Although cutaneous infection due to these microorganisms is rare, in selected cases it should be considered in the differential diagnosis.

Adult↗
PubMed1982

Unusual presentations of gonorrhea.

With the increasing incidence of gonorrhea, unusual clinical presentations of this disorder may be expected. In this report, two such cases are described. A male with primary infection of the penile skin due to gonorrhea and a female with gonorrhea-induced infection of accessory genital glands are presented. These cases illustrate the necessity to have a high index of suspicion to make the diagnosis of gonorrhea in light of atypical presenting signs or symptoms.

Adult↗
PubMed1982

Keratoacanthomas arising within a linear epidermal nevus.

An example of keratoacanthomas arising within a congenital linear epidermal nevus is documented. Previously reported cases indicate that squamous-cell carcinoma, basal-cell epithelioma, and keratoacanthoma may develop In linear epidermal nevi. Any recently appearing nodule in a linear epidermal nevus should raise the clinician's index of suspicion for one of these secondary tumors.

Adult↗