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Biomedical subjects

T Reich

Publications and source records attributed to T Reich.

At least 235 records · Page 13Linked to original sources
PubMedDate not supplied

Solvent use as a precursor to intravenous drug abuse.

Intravenous drug abuse (IVDA) is a significant public health threat, and ways of identifying individuals at high risk for IVDA are needed to plan strategies for intervention and treatment. Previous work had identified similarities in psychiatric diagnosis and patterns of drug use in IVDAs and solvent users. Using the same population, we found that 59 of 179 IVDAs (33.0%) reported a history of solvent use, which preceded the onset of IVDA in 41 of the 59. IVDAs with a history of solvent use were more likely to receive diagnoses of alcoholism and antisocial personality disorder (ASP) than IVDAs without solvent use. Even allowing for these coexisting psychiatric disorders, a reported history of solvent use increased the likelihood of also reporting IVDA by a factor of 3.2. Although the magnitude of risk is likely to differ in other populations, a history of solvent use may indicate individuals at high risk for IVDA, and youths who have used solvents should be considered at high risk for severe drug abuse, including IVDA.

Adult↗
PubMedDate not supplied

Prediction of intravenous drug use.

Information about lifetime intravenous drug use (IVDU) was obtained from 1,062 relatives of hospitalized alcoholics, felons, and control subjects, of whom 92 had a history of IVDU and an additional 230 had a history of substantial, but non-IV drug use. The IVDUs were significantly more likely than all other subjects to have reported experiencing numerous behavioral and social difficulties relating to conduct difficulties, early initiation of substance use, and disrupted living situation before the age of 15. They were also more likely to have exhibited conduct problems than other drug users. In multivariate analyses, four symptoms (fighting in school, juvenile arrest, initiation of cannabis use before 15, or initiation of sexual activity before 15) differentiated IVDUs. A history of greater numbers of these problems was associated with increasing risk for IVDU, both when compared with the total sample and when compared with other drug users.

Adolescent↗