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Biomedical subjects

T Pop

Publications and source records attributed to T Pop.

At least 217 records · Page 12Linked to original sources
PubMedDate not supplied

[Current possibilities of echography in pneumological diagnosis (preliminary note)].

Various types of echographies are presented, and it is concluded that the bi-dimensional echography, also called type B or echo-tomography is the most useful for the study of pulmonary affections, and of compact formations in contact with the pulmonary tissues. With the aid of Model E.D.B. Unirad sonograph (Technicare, USA), and of the Scintron 5 computer (Scintag, Berthold, Switzerland) 6 patients with pleurisy of various extension, one patient with fibrothorax, and 2 patients with pulmonary tumours have been examined. Five of the cases are presented. Echotomography has demonstrated its usefulness in measuring the thickness of the thoracic wall, in establishing by means of a non-invasive technique the solid or fluid character of pleural affections, in assessing the structure of pachypleuritis and in detecting changes induced by tumours, or atelectasia in the vicinity of the pleura. However, the method does not provide information on round peripheral tumours which do not come into contact with the pleura. Also this method cannot replace other methods already used in the pneumological practice, but can provide supplementary informations without any risks for the patient.

Female↗
PubMedDate not supplied

Down's syndrome. I. Cytogenetics.

A number of 107 children with clinical diagnosis of Down's syndrome have been studied. In 80% of the cases the parents have been cytogenetically investigated, too. Of these, 82.2% (88 cases) had free trisomy, 9.4% (10) had 46/47 + 21,4.7% (5 cases) had 14/21 translocation, 1 case (0.3%) had 21/21 translocation, one case translocation in inverse tandem, one case had iosochromosome 21, one case had 48.XXY + 21. These observations may be of help in establishing the prophylaxis of the syndrome, i.e.; 1. Cytogenetic investigation of all children suspect of having Down's syndrome, and in the case of translocation, of their parents as well. In the case of hereditary translocations it is recommended that the whole kinship be studied; 2. Monitoring of pregnancies of mothers over the age of 35 seems necessary.

Adult↗
PubMedDate not supplied

Familial Down's syndrome.

Investigation of an intensely consanguinized family in which three children were born with Down's syndrome (in one of them the diagnosis was uncertain) suggests the existence of a gene that favours chromosomal non-disjunction. In the same family there were two children with multiple malformations and two with neoplasia.

Abnormalities, Multiple↗
PubMedDate not supplied

Turner's syndrome with sympathoblastoma.

A case of Turner's syndrome clinically and cytogenetically diagnosed in a 15-year old girl is reported. At age 4 the girl was hospitalized for renal malformations (doubling of the urethra and its ectopic opening). Laparatomy revealed a small tumoral formation which was removed. The diagnosis established anatomo-histologically was of sympathoblastoma. Since the tumor is genetically conditioned by an autosomal mutation, association of the gonosomial anomaly and sympathoblastoma is supposed to be fortuitious though it is not improbable that the tumor be the result of an embryonar disorder favourized by the chromosomal anomaly.

Adolescent↗
PubMedDate not supplied

Functional peculiarities of the heart in the aged.

The dynamics of the heart contraction was studied on 126 subjects of different age (3rd--8th decades), using the classical noninvasive method, and the electrocardiogram, the phonocardogram and the external carotid arterial pulse were simultaneously recorded. In a smaller number of cases there was recorded the apexcardiogram or the echogram of the mitral valve. There was ascertained a prolongation of the pre-ejection period (PEP) with advance in age, while the left ventricular ejection time (LVET) was not significantly modified. The LVET/PEP ratio decreased significantly with age. The isovolumic relaxation time, estimated by means of the apexcardiogram, was prolonged in the aged subjects. The echogram of the mitral valve showed a diminution of the E--F slope, demonstrating that the filling rate in the protodiastole decreases in the advanced age. This decrease may reflect a reduction with age in the rate of the opening movement of the mitral valve imposed by the inherent modifications either of the mitral valve or of the left ventricle. The delay of the protodiastolic filling of the ventricle can be attributed to the slowing down of the ventricle relaxation or to the increase of the left ventricle wall stiffness in the aged.

Adult↗
PubMedDate not supplied

New possibilities in colour echotomography (computer-aided colour echotomography).

The present work discusses the technical bases and clinical significance of colour echography. Connecting the echograph to a high capacity computer through a Videotron permits the processing of colour images with the help of clinical programmes. This increases the accuracy of the diagnosis, and broadens the sphere of application of echography.

Color↗