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Biomedical subjects

T Ogata

Publications and source records attributed to T Ogata.

At least 505 records · Page 28Linked to original sources
PubMed1977

Modified Heineke-Mikulicz pyloroplasty as an effective gastric drainage procedure.

Rats were prepared with modified Heineke-Mikulicz pyloroplasty with longitudinal seromuscular incision, centering at pyloric ring, separation of submucosal layer around the pylorus and addition of transverse closure. This procedure combined with vagotomy was applied to the rats with cortisone administration and obstructive jaundice or exposure to the restraint plus cold water stress. Pyloroplasty and vagotomy seemed to prevent the occurrence of the severe damage on gastric mucosa without any suture line leakage whereas. Control rats had often erosive gastritis or hemorrhage.

Animals↗
PubMed1977

Biological and immunological studies on two substrains, c-1 and c-3, derived from the Nakayama-NIH strain of Japanese encephalitis virus.

A comparative analysis was performed on two substrains, c-1 and c-3, derived from the Nakayama-NIH strain of Japanese encephalitis virus. The infectivity of the two substrains was inactivated at similar rates by treatment with Tween 80 and Tween 20 but not by treatment with Tween 60. However, hemagglutinating activity as measured at pH 6.8 of the c-3 substrain treated with Tween 80 was more labile than that of the c-1 substrain treated with Tween 80. Also, the immunogenicity (neutralizing and hemagglutination-inhibiting antibodies) was different between the two substrains in sensitivity to low pH (6.8) and to Tween 80. With the c-1 substrain a combination of these treatments reduced the immunogenicity, but each treatment applied singly did not materially reduce it. The immunogenicity of the c-3 substrain was reduced by single as well as combined applications of the two treatments. Evidence was obtained which suggested that the part of the antigen sensitive to these treatments was strain-specific, whereas the resistant antigen was common among the Japanese encephalitis-St. Louis encephalitis complex members.

Animals↗
PubMed1977

Bronchoplastic procedures for lung cancer.

Twenty patients with lung cancer have undergone bronchoplastic procedures September, 1965, to June, 1976 in our hospital. Bronchoplastic procedures are considered to be indicated for early cases of hilar lung cancer rather than for somewhat advanced cases. Endoscopic examination and roentgenograms of the bronchial arteries are needed to delineate resectional lines of bronchus, the former for deciding the mucosal extent and the latter the intrabronchial extent of the tumor. The bronchoplastic procedures we adopted were free from the risks and dangers generally accompanying the operation, and there were no postoperative deaths. For the prevention of postoperative complications, careful attention to suture technique is needed, and postoperative bronchoscopic suction of intrabronchial secretions is absolutely necessary. These procedures assure good quality of life postoperatively and improvement in the survival rate by preserving pulmonary function, enhancing curability, and increasing the operative indications. These advantages warrant high evaluation of the operation.

Adult↗
PubMed1977

Effect of corticosteroid treatment on bilirubin metabolism in chronic aggressive hepatitis.

The metabolism of unconjugated bilirubin from the plasma was studied in 17 patients with chronic hepatitis and 7 normal subjects following a single injection of bilirubin of 2 mg per kg body weight. From the plasma disappearance curves of unconjugated bilirubin, hepatic uptake, reflux from the liver to the plasma and hepatic conjugation were calculated by 2 compartmental analysis. The clearance remained within normal range in 5 patients with chronic persistent hepatitis but was significantly impaired in 12 patients with chronic aggressive hepatitis, in which corticosteroid treatment improved the clearance significantly (p less than 0.01). Since urinary excretion of d-glucaric acid remained unchanged by corticosteroid treatment, the improved clearance may be attributable to increased hepatic parenchymal function.

Adult↗
PubMed1976

An electron microscopic study of the ciliated cells in the human gastric mucosa.

Ciliated cells were found in the mucosa of the human stomach in three patients. In two cases they occurred in the pyloric mucosa of patients with intestinal metaplasia who were operated on for duodenal ulcer. In the other case, they occurred within a polypoid lesion. They were located in small limited areas. The cells were densely ciliated, each cilium showing a typical 9+2 fibrilar pattern. Ciliated cells are not found in normal gastric mucosa and this suggests that they occur only in pathologically altered mucosa.

Adult↗