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Biomedical subjects

T Ogata

Publications and source records attributed to T Ogata.

At least 487 records · Page 27Linked to original sources

The outcome from acute subdural haematoma following decompressive hemicraniectomy.

Retrospective analysis of 15 cases with acute subdural haematoma receiving decompressive hemicraniectomy was carried out in an effort to clarify the beneficial effect and limitation of this operative procedure. The patients in this series were divided into three groups according to postoperative intracranial pressure (ICP). Decompressive hemicraniectomy was effective in lowering ICP in all patients except for the cases that developed acute brain swelling. Overall mortality rate was 66.7% in this series. Preoperative clinical status, and intra- and postoperative ICP and CT findings obtained within 24 hours of operation were correlated with the operative outcome.

Acute Disease↗

Thoracic duct cyst of the mediastinum.

A case of mediastinal thoracic duct cyst is described. It is believed to be the first to be diagnosed before thoracotomy. Seven surgically treated cases have been reported but in none was the diagnosis made before operation. This case report concerns a 49-year-old woman who was operated upon because of a thoracic duct cyst that had been diagnosed by lymphangiography before the operation. Symptoms were caused by pressure of the cyst on the esophagus. The operation and immediate postoperative course were uneventful. One year later, the patient was doing well and no further investigation was recommended.

Adult↗

High-performance liquid chromatographic determination of free and total polyamines in human serum as fluorescamine derivatives.

A highly sensitive and simple fluorimetric method for the determination of free and total polyamines, spermidine, spermine, putrescine and cadaverine, in human serum by high-performance liquid chromatography is described. The polyamines, obtained after clean-up of deproteinized serum by Cellex P column chromatography, are converted to their fluorescamine derivatives in the presence of nickel ion which inhibits the reaction of interfering amines with fluorescamine, and the derivatives are separated simultaneously by reversed-phase chromatography (LiChrosorb RP-18) with a linear gradient elution. The lower limits of detection are 10 and 15 pmole for spermine and the others in 0.5 ml of serum, respectively.

Adult↗

Venous angioma of the neck in a child.

Venous vascular masses in the neck are rare entities in the pediatric population. Aneurysmal dilatation or ectasia of the superficial cervical vein, the so-called "venous angioma" is a very uncommon condition. A 12-year old female with venous angioma involving the right neck is described. The preoperative diagnosis was confirmed by angiography.

Aneurysm↗

Geographic distribution of arbovirus antibodies in indigenous human populations in the Indo-Australian archipelago.

Sera from lifetime residents in 16 localities of the Indo-Australian archipelago and adjacent areas were tested for hemagglutination-inhibition antibody against four alpha-viruses (Sindbis, Getah, chikungunya, and Ross River) and for neutralizing antibody against six flaviviruses (dengue 2 and 3, Japanese encephalitis, Murray Valley encephalitis, Kunjin, and Edge Hill). Mosquito collections were carried out in some of the localities to study vector relationships to distribution of the arbovirus antibodies. Antibodies specific to Sindbis and Getah viruses were rare except in north Australia. Chikungunya virus-specific antibody was highly prevalent in localities of the Oriental zoogeographic region and Wallacea, rare in west New Guinea, and absent in north Australia. Age distribution of chikungunya antibody suggested that the antibody last occurred in most Indonesian localities about 30 years ago. Ross River virus-specific antibody was confined to localities of the Australian zoogeographic region. Antibodies reacting to dengue 2 and 3 viruses occurred in high frequency in the entire area of the archipelago. Antibodies specific to Murray Valley encephalitis and Kunjin viruses were also widespread although at a very low frequency. Japanese encephalitis virus-specific antibody was highly prevalent in areas west of Wallace's Line while it was absent in areas east of the line with the exception of Lombok. Antibody to Edge Hill virus was rare and confined to the Australian zoogeographic region. The distribution of arthropod vectors, vertebrate hosts, and of arboviruses are discussed in relation to zoogeographic divisions.

Age Factors↗

A scanning electron microscopic study on the fractured rat parietal cells in resting state and after stimulation with tetragastrin.

Parietal cells in the rat gastric mucosa fractured by freeze cracking methods under resting (control) state and tetragastrin stimulation were studied by field emission scanning electron microscopy. The structures thus revealed were compared with those studied by transmission electron microscopy. In the fractured cytoplasm, intracellular canaliculi lined by numerous microvilli invaginated deeply towards the basal cytoplasm. Tubulovesicles appeared as many small holes about 0.05mu in diameter and were distributed predominantly in the apical or pericanalicular cytoplasm. Some tubulovesicles directly opened into the secretory canaliculi. Occasionally, tiny microvilli appeared in tubulovesicles. After being stimulated for 30 min with tetragastrin, the secretory canaliculi of parietal cells became enlarged and there were a concomitant increase in both the number and size of microvilli. Tubulovesicles also were increased in size and number and the tiny microvilli in them were also increased. The tubulovesicles were enlarged presumably as a result of membrane fusion between contiguous tubulovesicles. It was found that the enlargement of the secretory canaliculi was the result of fusion of the membrane of a single tubulovesicle or a confluence of tubulovesicles to that of the secretory canaliculus and the successive disappearance of the fused membrane.

Animals↗