Biomedical subjects

T Nose

Publications and source records attributed to T Nose.

At least 253 records · Page 14Linked to original sources

PubMed1992

Giant aneurysm at the junction of the left internal carotid and persistent primitive trigeminal arteries--case report.

A 67-year-old female presented with an unruptured giant aneurysm at the junction of the left internal carotid artery (ICA) and the persistent primitive trigeminal artery (PTA), manifesting as progressive left abducens nerve paresis. The PTA was clipped by the left suboccipital approach. The aneurysm was then successfully thrombosed by ligation of the left ICA at the cervical portion following left superficial temporal artery-middle cerebral artery anastomosis. The left abducens nerve paresis improved postoperatively. Magnetic resonance imaging was of considerable value in the pre- and postoperative evaluation of the giant aneurysm.

Abducens Nerve↗

PubMed1992

[A case of asymptomatic Dandy-Walker syndrome with cerebellar hemorrhage].

A case of asymptomatic Dandy-Walker syndrome (DWS) complicated by cerebellar hemorrhage is reported. A 65 year-old man was hospitalized for investigation and treatment of disturbance of consciousness. CT scan and MRI showed a large hematoma in the posterior fossa cyst. Postoperative CT scan and MRI revealed the DWS and cerebellar hemorrhage on the left side. This patient had no symptom until 65 years of age, in spite of having DWS. There has been no such case reported in the literature to our knowledge. Derangement of secretion and absorption of cerebrospinal fluid seem to have been the cause of late-onset symptoms after a long well balanced symptom-free period.

Aged↗

PubMed1992

[Analysis of stereoisomers involved products of synthesized 18F-2-deoxy-2-fluoro-D-glucose by 1H-NMR spectroscopy].

18F-2-fluoro-2-deoxy-D-mannose (FDM) is eventually involved in side products of 18F-2-fluoro-D-glucose (FDG) synthesized by the acetylhypofluorite method. We attempted the measurement of existence ratio of FDM and FDG, FDM alpha and FDM beta, FDG alpha and FDG beta by 400 MHz 1H-NMR spectroscopy. The ratio of FDM to FDG were 4.0%. The amounts of FDG beta were much larger than those of FDG alpha. The difference between the amounts of FDM alpha and FDM beta were not significant. 1H-NMR spectroscopy could be utilized in quantitative analysis of products and byproducts in cyclotron chemicals. The FDM in FDG synthesized in our cyclotron system was not considered to affect a lot of influence in PET study.

Deoxyglucose↗

PubMed1992

[Treatment of metastatic brain tumors: effect of surgery of multiple metastatic brain tumors and systemic metastasis with special reference to quality of life].

To assess the efficacy of surgical resection of brain metastases from patients with multiple brain metastases or/and with other systemic metastases, the authors analysed treatment results of 90 cases of metastatic brain tumors. The patients were divided into three groups. Group A (nine cases): Patients with single brain tumor and their primary cancers were well controlled. Their brain tumors were removed surgically and followed by radiation. Their mean survival time was 17.0 months, and 14.6 months were independent (Karnofsky score greater than or equal to 70) in cases of lung cancer. Five patients (55.6%) improved by treatment. Group B (21 cases): Patients with multiple brain metastases or/and with systemic metastases. Their brain tumor(s) which gave rise to neurological symptoms were surgically removed in order to improve their quality of life. In cases of lung cancer, mean survival time was 9.5 months and 7.1 months were independent. 11 patients (52.3%) improved by treatment. Group C (60 cases): Patients treated conservatively. Their mean survival time was 4.9 months and 2.7 months were independent in cases of lung cancer. Only 13 patients (21.7%) improved by treatment. However 23 (38.3%) deteriorated in their quality of life during treatment. Two patients of this group had single brain tumor and their primary cancers were controlled well. They refused surgery. Their mean survival time was 13.0 months, and 7.0 months were independent. These times were statistically shorter than group A. Seven patients had similar systemic and neurological states as those in group B. Their mean survival time was 5.0 months and 3.0 months were independent. These times were also statistically shorter than those in group B.(ABSTRACT TRUNCATED AT 250 WORDS)

Brain Neoplasms↗

PubMed1991

Reversible porencephaly. Alteration of the cerebrospinal fluid flow after shunt malfunction.

The cases of four infants (five lesions) are reported, where "porencephalic cysts," located along the ventricular catheter after shunt malfunction and Ommaya reservoir insertion, disappeared after ventriculoperitoneal (VP) shunt revision and combined cyst peritoneal (CP) shunt, or after VP shunt alone. This pathological state is thought to be a rare postoperative complication. Its pathogenesis and therapy are discussed. Shunt malfunction or Ommaya reservoir insertion may result in a hypertensive hydrocephalic state. Cerebrospinal fluid (CSF) flows out through a catheter penetrating the site of the ventricular wall and expands in the surrounding white matter to form a porencephalic cavity. Once this porencephalic state occurs, it will not disappear spontaneously because the CSF flows in one direction. As treatment for closed porencephaly, CP shunt following a VP shunt revision was markedly effective; for communicating porencephaly, a VP shunt revision alone was effective.

Brain↗

PubMed1991

Normal brain damage after radiotherapy of brain tumours.

A total of 106 patients were examined for adverse effects to the brain from 60Co or proton radiotherapy. Radiation induced change (RIC) developed within the irradiated field 40-60 months after doses of 800-1000 neuNSD or 70 TDF and in 10-20 months after doses of more than 1700 neuNSD or 100 TDF. The incidence of RIC increased significantly with increasing age. Furthermore pathological changes like oedema and infarction in the brain tissue may be an important factor for the development of RIC in the central nervous system (CNS).

Adult↗

PubMed1991

Radiolucent osteoma of the skull: case report.

A rare case of a radiolucent osteoma of the skull is reported. The radiological and pathological findings of this lesion, including magnetic resonance imaging findings, are presented, and the efficacy of magnetic resonance imaging for the diagnosis of this skull tumor is evaluated. The differential diagnosis of radiolucent bone tumors is discussed.

Child↗

PubMed1991

Response of capsaicin pretreated skin blood vessels to exercise.

Six normal men performed cycle ergometer exercise from 50 W to 125 W in a room maintained at 26 degrees C. Capsaicin was introduced by iontophoresis into the forearm skin. Forearm skin blood flow (FSBF) during graded exercises before and after capsaicin treatment was measured by laser Doppler flowmetry. Forearm skin blood flow before capsaicin treatment increased depending on the intensity of exercise. However, forearm skin blood flow 24 hours after capsaicin treatment scarcely increased during graded exercise. The cause of this capsaicin effect was discussed.

Adult↗

PubMed1991

[Amplification of L-myc oncogene in malignant meningioma. Case report].

Amplification of L-myc oncogene was noticed in a malignant meningioma originating from the right sphenoidal wing of a 54-year-old female. The patient underwent three surgical resections plus radiotherapy over a period of 11 years and then the growth rate of the tumor became much greater with a severely invasive appearance. Using Southern blot hybridization, L-myc amplification was examined on the specimen resected at the fourth operation. As a result, approximately five-fold amplification was confirmed, which has not been previously reported except for that in a small cell carcinoma of the lung. This result may suggest that L-myc amplification is responsible to some extent for the malignant transformation in this meningioma.

Female↗

PubMed1991

Isolated cerebral varix with magnetic resonance imaging findings--case report.

A rare case of isolated cerebral varix of the left deep sylvian vein was discovered incidentally in an 11-year-old boy by computed tomographic scanning, magnetic resonance (MR) imaging, and cerebral angiography. MR imaging was most useful in diagnosis of cerebral varix. Review of 21 similar reported cases shows no significant in age, sex, location, or size character.

Brain↗

PubMed1991

Aspergillus mycotic aneurysm--case report.

A 61-year-old female developed subarachnoid hemorrhage after trans-sphenoidal surgery for Rathke's cleft cyst. Neuroradiological examination revealed a large aneurysm at the C1 portion of the right internal carotid artery. Autopsy revealed marked proliferation of aspergillus hyphae in the wall of the aneurysm. A review of previously reported cases of fungal aneurysm proposes two developmental processes. Aneurysms secondary to fungal meningitis tend to be large in size and located in the major cerebral artery trunk, but aneurysms following fungal sepsis tend to be small and in peripheral branches. The former aneurysms are probably caused by fungus invasion into the intracranium, usually from the paranasal sinus, and the latter may be due to fungal emboli like bacterial emboli in bacterial endocarditis. Ruptured fungal aneurysms are difficult to treat, so fungal meningitis or sepsis must be eradicated before an aneurysm develops.

Aneurysm, Infected↗

PubMed1991

Portable digital subtraction angiography in the operating room and intensive care unit.

A simple, inexpensive method of portable digital subtraction angiography (DSA) using an image processor (Sigma X), still-videorecorder and control panel combined with a surgical x-ray television unit can provide real time subtraction images on the monitor. This portable DSA unit was used in 161 cases (130 in the operating room and 31 in the intensive care unit). In the operating room it is useful: 1) to confirm patency of the parent artery and its branches after aneurysm clipping, 2) to identify feeding arteries of arteriovenous malformation and to confirm total extirpation, 3) to confirm the patency of extracranial-intracranial bypass, 4) to confirm patency of the internal carotid artery and absence of flap formation after carotid endarterectomy. In the intensive care unit, it is particularly useful for visualizing cerebral vasospasm after subarachnoid hemorrhage and recanalization of an occluded major intracranial artery. Absence of intracranial circulation can be demonstrated in patients with suspected brain death.

Angiography, Digital Subtraction↗

PubMed1991

Central nervous system metastasis from gallbladder carcinoma--case report.

Systemic metastases from gallbladder carcinoma occur frequently, but involvement of the central nervous system is rare. We describe such a case in a 68-year-old female. Solitary brain metastasis from gallbladder carcinoma was completely removed 4 months after operation for the primary tumor. Planned chemotherapy was then given to prevent recurrence. She was leading a normal life 4 years later. Patients with solitary brain metastasis from gallbladder carcinoma can achieve a better outcome and longer survival after removal of the brain metastasis if there is no other metastasis.

Adenocarcinoma↗

PubMed1991

Large arteriovenous malformation associated with persistent primitive hypoglossal artery--case report.

A rare case of large arteriovenous malformation (AVM) with persistent primitive hypoglossal artery in a 43-year-old male was treated by staged embolization, followed by total removal. AVM associated with carotid-basilar anastomosis is quite rare, but the incidence of AVM in patients with carotid-basilar anastomosis is high. AVM associated with persistent carotid-basilar anastomosis has no distinguishing features compared with ordinary AVM, but participation of the posterior circulation as a feeder is characteristic.

Adult↗

PubMed1991

Diagnostic value of finger systolic blood pressure in the assessment of vasospastic reactions in the finger skin of vibration-exposed subjects after finger and body cooling.

To assess the severity of vibration-induced white finger (VWF), finger systolic blood pressure (FSBP) after finger cooling and after combined finger and body cooling was measured by strain-guage plethysmography for 100 vibration-exposed men and 22 healthy men. The exposed men were classified as being without VWF (EW), with mild VWF (EM), and with severe VWF (ES) according to records of blanching attacks. FSBP was significantly reduced only in the ES group after finger cooling and in the ES and EM groups after both body and finger cooling. The diagnostic sensitivity and specificity for VWF was 81.7 and 90.3%, respectively. Skin temperature measurements before and after immersion in cold water (5 degrees C, for 10 min) could not be used for the estimation of VWF severity.

Adult↗

PubMed1991

[Ultrastructure of glioma vessel--morphometric study for proliferative potential of endothelial cell].

In this study we quantified the morphological abnormalities of human glioma vasculature in operated sample of low grade astrocytomas and malignant gliomas. Only those vessels with a diameter of less than 10 micron and containing one nucleus at least on axial section present in the marginal area of the tumors devoid of necrosis were subjected to the present study. A total of 58 vessels were analyzed with computer assisted morphometry for ultrastructural evidence of proliferative potentials of endothelial cells. 5 specific features of the endothelial cells and/or the capillaries which were not related to the vascular permeability were assessed: (1) Degree of vascular luminal narrowing (LN: Ratio of luminal area to abluminal area), (2) Thickness of basement membrane (BM), (3) Mean % ratio of the endothelial cells including Weibel-Palade bodies to whole endothelial cells (WPB-1) and the number of Weibel-Palade bodies in an endothelial cell section (WPB-2), (4) Irregularity of nuclear shape (NA: semiquantified grade 0 to 3). (5) Mitochondrial density (MIT). We found that: (1) LN was significantly stronger in malignant glioma capillaries (MGC, 28%) than low grade astrocytoma capillaries (LAC, 39%). (2) BM was significantly thicker in MGC (2.9 microns) than in LAC (1.2 microns), (3) WPB-1 and WPB-2 were significantly higher in MGC (34% and 0.92) than LAC (14% and 0.39). (4) NA was significantly higher in MGC (grade 2.1) than LAC (grade 1.3), (5) MIT was significantly higher in MGC (5.6%) than LAC (4.2%).(ABSTRACT TRUNCATED AT 250 WORDS)

Astrocytoma↗

PubMed1991

[The actual situation in surgical management of occlusive cerebrovascular disease].

We studied 828 cases with occlusive cerebrovascular disease who were admitted to our hospital over these 5 years in relation to surgical management. Cerebral angiography including digital subtraction angiography was carried out in 770 cases. Surgical management was carried out in 110 cases; 77 cases of carotid endarterectomy (CEA), 18 cases of EC-IC bypass and 15 cases of external decompression. The ratio of surgical management was 13. 3% of all cases admitted. The mortality and the morbidity were 5.4% and 1.8% respectively. The number of EC-IC bypass has decreased gradually after the reports of international cooperative study concerning with EC-IC bypass in 1985. But the number of CEA has increased gradually.

Aged↗

PubMed1991

[Bilateral traumatic hemorrhage in the basal ganglia: report of two cases].

Hematomas of the basal ganglia in head injury have long been recognized by pathologists with an interest in head injury but their mechanism has not been revealed clearly. We report two cases of bilateral traumatic hemorrhage in the basal ganglia. Case #1, a 17-year-old male was admitted to our hospital immediately after a traffic accident. Neurological examination revealed that the patient was comatose and had right hemiparesis. CT scan showed bilateral hemorrhage of the basal ganglia and subarachnoid hemorrhage in the perimesencephalic cistern. MRI showed high signal intensity areas in the bilateral basal ganglia, perimesencephalic cistern, cerebral white matter and corpus callosum. The patient was diagnosed as having diffuse axonal injury coinciding with bilateral hemorrhage of the basal ganglia. Stereotactic aspiration for the hematoma of the left basal ganglia was carried out. Case #2, a 75-year-old male was admitted immediately after falling from the roof of his house. Neurological examination revealed no neurological deficit except for headache and nausea. CT scan on the day of injury revealed no abnormality. But CT scan 12 hours following the injury showed bilateral hemorrhage of the basal ganglia. Blood pressure of the patient was within normal range and he was diagnosed as having traumatic bilateral intracerebral hematoma. Conservative treatment was carried out and the patient was discharged 7 days after injury with no neurological deficit. The mechanism of traumatic hemorrhage of the basal ganglia has not been clear. In case #1, diffuse axonal injury (DAI) may have played an important role in the bilateral hemorrhage. But in case #2, non-DAI factor such as vasoparalysis syndrome may have existed.(ABSTRACT TRUNCATED AT 250 WORDS)

Accidental Falls↗