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T Nohara

Publications and source records attributed to T Nohara.

143 records · Page 8Linked to original sources
PubMed1982

Effects of carbon dioxide on serum biochemical patterns and on histopathological changes of organs in rats.

The effects of carbon dioxide on serum biochemical patterns and on histopathological changes of organs were studied in male Sprague-Dawley rats which were anesthetized with a mixture of 40% carbon dioxide and 60% oxygen for 3 hr. This level of carbon dioxide is sufficient to maintain rats at an anesthetized level. There were gradual decreased in respiration, body temperature, heart rate, blood pressure and blood pH. At the same time there were significant increases in organ weight (lungs and kidneys), and in exudate to thorax, hematocrit, and serum biochemical patterns (glucose, phosphorus, uric acid, blood urea nitrogen, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase and alpha-hydroxybutyrate dehydrogenase). The weight of the liver, however, decreased slightly. There were minor abnormalities in both gross anatomy and histology (lungs, liver and kidneys). When the rats inhaled ordinary air, they awoke within a few minutes and recovered normal hematological level (pH 7.3, PaO2 120 mmHg and PaCO2 45 mmHg) within 24 hr.

Anesthesia↗
PubMed1982

Levels of CO2 in arterial blood of carp under carbon dioxide anesthesia.

The application of carbon dioxide anesthesia to fish has been studied in order to find a method of transport of live fish. In the continuation of this study, the levels of arterial PaO2, PaCO2 and pH were examined in carp anesthetized with carbon dioxide. In the initial stage of the anesthesia, both PaO2 and PaCO2 increased. In the following stage, PaCO2 gradually decreased. An increase or decrease in PaO2 seems to depend on the levels of PaCO2 during anesthesia. On the other hand, ECG (electrocardiogram) profiles of anesthetized carp indicate that a gradual increase in R-R interval is coupled with a gradual decline of the opercular rate.

Anesthetics↗
PubMed1980

Eccrine poroma.

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Adenoma, Sweat Gland↗
PubMed1974

Influence of changes in heart rate, aortic pressure and flow rate upon experimental coronary insufficiency.

This study was designed to evaluate the role of heart rate, aortic pressure, and aortic flow in the development of coronary insufficiency following acute coronary stenosis. In dogs, each of these parameters was controlled at a predetermined level while the left anterior descending coronary artery was constricted with a small screw clamp. The critical coronary pressure (CCP), i.e. the pressure below which a rise of left atrial pressure could be detected, was determined at various levels of hemodynamic load. Increases in aortic pressure, elevation of the heart rate and an increase in aortic flow rate were all associated with an elevation of the CCP and an increase in tension-time index (TTI). The changes in CCP were most striking when TTI was increased by aortic flow rate change. These findings suggest that with high aortic pressure, further constriction of coronary artery is required to precipitate coronary insufficiency, that the level of pacing required to induce coronary insufficiency is a useful index in assessing the degree of coronary stenosis, and that an augmentation of aortic flow rate is an important factor in the initiation of coronary insufficiency.

Animals↗