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Biomedical subjects

T Nasemann

Publications and source records attributed to T Nasemann.

At least 55 records · Page 3Linked to original sources
PubMed1980

[Clinical aspects and importance of human herpex simplex infections. Results of herpes antigen therapy].

Herpes simplex diseases are among the most frequent sociomedical problems of our age. For the patients the recurrent diseases are particularly distressing depending on the frequency of relapse, their localization and clinical course. Immunological factors, especially cellular immune mechanisms seem to affect the frequency of relapse and particularly the clinical course of the relapse. Clinical experience so far with immunotherapy of relapsing herpes diseases with heat-inactivated herpes simplex virus antigen type 1 and type 2 are optimistic. Local painful swellings or more rarely the appearance of an urticaria have been described as side-effects within 10 years in 1 to 2% of patients.

Antigens, Viral↗
PubMed1979

Vaccination for herpes simplex genitalis.

Type-specific vaccines containing heat-inactivated herpes simplex hominis virus type 1 or 2 have been developed for the treatment of herpes simplex genitalis. When patients with recurrent herpes genitalis were treated with the type 2 vaccine the clinical course of the disease improved and the eruption-free interval was extended. In severe cases, especially in permanent genital herpes, the concurrent administration of vaccine and immunoglobulin concentrates improved the clinical course of the disease. Antibody titres and the in-vitro stimulation of lymphocytes with phytohaemagglutinin or herpes simplex hominis virus antigens remained constant during administration of the vaccine.

Female↗
PubMed1979

[Cancer en cuirasse, induced by a malignant mixed salivary gland tumor].

A case of cancer en cuirasse is reported, deriving from a metastasizing malignant mixed tumor of the lacrimal gland. Based on histological criteria, the primary benigne prognosis of mixed tumors of lacrimal glands is discussed. According to sensitivity testing to cytostatic agents treatment with 375 mg of bleomycin achieved a recurrence-free interval of eight months. Pathogenesis of secondary effects are discussed (so-drug-induced called bleomycin-lung).

Adenoma, Pleomorphic↗
PubMed1978

[Viral acanthomas and specialized forms of keratinosome "membrane coating granules" (author's transl)].

In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to keratinosomes. A particularity in condylomata acuminata are the "wagon-wheel" bodies. These structures are typical for the non keratinazed squamous epithelium. The participation of intercellular extruded "wagon-wheel" bodies, MVB and atypical keratinosomes on an irregular baso-apical diffusion-barrier in the epidermis of cases with viral acanthomas has been discussed. On the basis of the relation seen between MVB and the Golgi-apparatus, their transition to partially atypical keratinosomes in cases of viral acanthomas and their "expulsion" into the intercellular space could indicate that in keratinozytes the enzymatically regulated feed-back between the cellular surface and the capability to synthesize is changed by viral agents. The interference appears to manifest itself in the Golgi-apparatus and also appears to be "specified" by the terrain present.

Condylomata Acuminata↗
PubMed1978

[Viral acanthomas and specialized forms of keratinosome "membrane coating granules" (author's transl)].

In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to keratinosomes. A particularity in condylomata acuminata are the "wagon-wheel" bodies. These structures are typical for the non keratinazed squamous epithelium. The participation of intercellular extruded "wagon-wheel" bodies, MVB and atypical keratinosomes on an irregular baso-apical diffusion-barrier in the epidermis of cases with viral acanthomas has been discussed. On the basis of the relation seen between MVB and the Golgi-apparatus, their transition to partially atypical keratinosomes in cases of viral acanthomas and their "expulsion" into the intercellular space could indicate that in keratinozytes the enzymatically regulated feed-back between the cellular surface and the capability to synthesize is changed by viral agents. The interference appears to manifest itself in the Golgi-apparatus and also appears to be "specified" by the terrain present.

Animals↗
PubMed1977

[Annulate nexus and "virus like particles" (author's transl)].

Dependent on the direction in which the specimens are sectioned annular shaped nexus of neighbouring cell membranes may be misinterpreted as "virus like particles". It is suggested that many of the "virus like particles" described in tumor research may be annulate nexus.

Animals↗
PubMed1977

Cutaneous osteomas: a clinical and histopathologic review.

In 20 000 consecutive skin biopsies we found 35 cutaneous osteomas. Ten were primary while 25 appeared secondary to another abnormality. Associated with ossification were Malherbe's calcifying epithelioma, basal cell carcinoma, nevus cell nevus, appendageal and fibrous proliferations, inflammation, trauma, and calcification. Cutaneous bone formation appears to be either a hamartomatous or metaplastic phenomenon.

Adult↗
PubMed1977

[Juvenile warts].

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Age Factors↗