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Biomedical subjects

T Nasemann

Publications and source records attributed to T Nasemann.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Comparative testing of Kamillosan cream and steroidal (0.25% hydrocortisone, 0.75% fluocortin butyl ester) and non-steroidal (5% bufexamac) dermatologic agents in maintenance therapy of eczematous diseases].

We report on 161 patients suffering from inflammatory dermatoses on hands, forearms, and lower legs who had been initially treated with 0.1% difluocortolone valerate. During the maintenance therapy carried out over a period of 3 to 4 weeks, we tested the efficacy of Kamillosan cream vs. 0.25% hydrocortisone, 0.75% fluocortin butyl ester, and 5% bufexamac in a bilateral comparative study. For the indications tested Kamillosan cream showed more or less equieffective therapeutic results as compared to 0.25% hydrocortisone. It is superior, however, to the non-steroidal anti-inflammatory agent 5% bufexamac as well as to 0.75% fluocortin butyl ester, a further glucocorticoid. With regard to neurodermitis, Kamillosan cream not only shows the same therapeutic effect as 0.25% hydrocortisone but is even of marked superiority towards other reference products.

Adolescent↗
PubMed1985

[Hereditary papulotranslucent acrokeratoderma].

Hereditary papulostranslucent acrokeratoderma is known as a rare genetic cutaneous disorder. Clinically it shows white translucent papules with a smooth surface affecting hands and feet, especially palms and soles, but there is no subjective discomfort. Histologic study reveals signs of focal hyperkeratosis, hypergranulosis, and acanthosis without any alteration of the dermis.

Adult↗
PubMed1985

[Differential x-ray therapy of keratoacanthoma. A clinical case].

Differential radiotherapy is a way of making a diagnosis and treatment for keratoacanthoma at the same time. After having taken a punch biopsy in order to exclude basal cell carcinoma, we give an X-ray dose of 2500 r. This dose is sufficient to induce the healing of keratoacanthoma. If there is no tendency of healing, the tumor must be a squamous cell carcinoma. In this case, we apply the full tumor dose of totally 5000 r.

Aged↗
PubMed1984

[Clinical variability of polyvinylpyrrolidone dermatosis].

Several pharmaceutics on the market contain polyvinylpyrrolidone (PVP). As the high-polymeric parts of the PVP molecules cannot be eliminated after parenteral or subcutaneous application, they accumulate in the organism. PVP residues in the dermis cause a considerable variability of skin changes, ranging from deposits nearly without reactions up to swelling, papules, granulomas and pseudotumors.

Dermatitis, Contact↗
PubMed1984

[Bullous pemphigoid in childhood].

Bullous pemphigoid is a rather rare disease in childhood. A case report is given about a seven-year-old girl suffering from juvenile bullous pemphigoid and the differential diagnosis is discussed with regard to the other bullous diseases in children. Some clues were noted in the case history of our patient concerning an effective treatment using erythromycin in bullous pemphigoid. A short summary is presented about the theoretical basis with respect to this therapeutical procedure.

Age Factors↗
PubMed1982

[New aspects in infections with herpes-simplex-virus (author's transl)].

The high and increasing incidence of herpes simplex (HSV) diseases has led to increasing research activities at all levels all over the world. Particularly important for clinicians are 1. new aspects of the potential danger for certain patients, e.g. the newborns or the immunosuppressed, by exogenous herpes infections or reactivated latent virus and 2. new epidemiological or diagnostic aspects and 3. the problems with the advances, failure and evaluation of chemo- and immunotherapy.

Herpes Simplex↗
PubMed1981

[Electronmicroscopic investigations of lichen sclerosus et atrophicus of the vulva after cryosurgery (author's transl)].

A female with lichen sclerosus et atrophicus of the vulva, which had been treated by intralesional corticosteroid injection and vulvectomy showed again a recurrence of the disease. This time the lesion was treated by cryosurgery. The diseased tissue was investigated by electronmicroscopy during the consecutive phases of the procedure of cryosurgery.

Adrenal Cortex Hormones↗
PubMed1981

[Histologic and electron microscopical investigations in a patient with benign verrucosis generalisata (author's transl)].

A report is given on a 43-year-old man who has been suffering from pointed condylomata in the region of scrotum and anus since 1975. Repeated relapses. Since 1977 verrucous lesions spreading from thorax to both arms and the throat. Histologic examination revealed intraepidermal foci of balloon cells in the stratum spinosum and stratum granulosum, partly with intranuclear basophilic inclusions. Electron microscopy showed an intact basal lamina and also partly intact epidermis. Only in the focal area the epidermopoiesis is disturbed already from the basal layer, with vacuolated destruction of the basal keratinocytes and condensation of the cytoplasm, as well as formation of myelin figures. This degenerative process together with enlarged intercellular spaces and partly conserved desmosomes continues into the stratum granulosum. From the upper stratum spinosum balloon cells characteristic for warts are found. In the stratum granulosum there are abundant atypic keratohyalin granules, and in the stratum granulosum and stratum corneum characteristic virus-containing kerationcytes are found. Furthermore, there are lots of released virus elementary bodies deposited in bizarre shapes at the horny lamellae: crystalloid or garland-, chain-, letter-, or wreath-shaped.

Humans↗