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Biomedical subjects

T Nakata

Publications and source records attributed to T Nakata.

At least 307 records · Page 17Linked to original sources

Nature and distribution of mucosubstances in human mature enamel identified by enzyme electron microscopy.

Longitudinal slices of 12 freshly extracted human third molars fixed in 10 per cent neutral formalin were demineralized with 1M lactic acid. Ultrathin sections of slices were stained with ruthenium red or silver methenamine. The reaction products were mainly found in the prism sheath regions. To identify the mucosubstances, the digestion tests with chondroitinase ABC, AC, hyaluronidase and neuraminidase were performed. It was concluded that the major component of the organic matrix of inner human dental enamel is chondroitin 4-sulphate or chondroitin 6-sulphate localized in prism sheath regions and inter-crystalline spaces.

Chondroitin Sulfates↗

Results of aortic valve replacement in patients with a narrow aortic annulus: effects of enlargement of the aortic annulus.

Among 71 patients who underwent aortic valve replacement with a Björk-Shiley prosthesis, 13 (18.3%) had concomitant enlargement of the aortic annulus at the noncoronary cusp. Mean age of the 13 patients at operation was 34.4 years. Nine of them had combined mitral stenosis. One patient died in the early postoperative period, for an operative mortality of 7.7%. The aortic annulus before enlargement was 20.9 mm and after enlargement, 24.3 mm on the average. The net increase in diameter of the aortic annulus was 3.3 mm, which was statistically significant (p < 0.005). The tissue diameter of the prosthesis was 1.2 mm larger on the average than the aortic annulus diameter before enlargement, and a prosthesis at least one size larger could be implanted in the narrow aortic annulus.

Adolescent↗