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Biomedical subjects

T Nakada

Publications and source records attributed to T Nakada.

At least 595 records · Page 33Linked to original sources

Triple fossa metastasis of prostate cancer.

The radiological appearance of prostate cancer metastasis to the central nervous system often mimics meningioma. The bony change of prostate cancer metastasis resembles the hyperostosis of meningioma because of its blastic rather than lytic nature. On computed tomographic (CT) scan, like meningioma, prostate cancer metastasis enhances homogeneously after the infusion of contrast material. Triple fossa (middle, temporal, and orbital fossae) involvement by a solitary mass without bony destruction is thought to be highly specific for meningiomas. We report a case demonstrating the CT findings typical for a triple fossa meningioma caused by prostate cancer metastasis.

Adenocarcinoma↗

[Micrometastasis in the resected lungs of lung cancer patients with special reference to their clinical features].

The microscopic metastases were examined seemingly unaffected areas of the resected lungs in 116 primary lung cancer patients. In 55 patients (47%), micrometastases were found in the areas which looked normal. The investigation on the route and location of micrometastaes revealed that lung metastases were formed mainly through haematogenous and partly through lymphatic route. The high incidence of postoperative intrapulmonary spread in the positive micrometastasis group suggested that most of microscopic deposits would become distinct tumors in time. Thirteen patients have had a second operation for the intrapulmonary metastatic lesions. There was one postoperative death. Nine patients have subsequently died. Three patients are still alive and well without evidence of recurrence.

Adenocarcinoma↗

Theophylline-induced seizures: clinical and pathophysiologic aspects.

The clinical features and management of theophylline-induced seizures are not well appreciated in spite of their unique aspects. These seizures tend to occur in neurologically intact patients and leave no or only minor neurologic sequelae if controlled early. They begin with focal motor seizures with or without secondary generalization and are followed by stupor or coma. They are responsive only to adjustment of theophylline dosage. Should the motor phenomenon persist, it takes the form of epilepsia partialis continua. Extensive workup for a structural brain lesion may be unrewarding. The electroencephalogram typically shows periodic lateralized epileptiform discharges, which may provide a diagnostic clue.

Aged↗

Computed tomography of spinal cord atrophy.

Spinal cord atrophy takes on several different forms which correlate closely with specific clinical features. The majority of them, however, can be categorized into three distinct patterns, diffuse (transverse myelopathy), hemi- (Brown-Sequard syndrome), or anterior (anterior spinal artery syndrome) atrophy. Until recently, the differential diagnosis had been made solely on the neurological examination. We present three cases of spinal cord atrophy, one in each category. Spinal computed tomography with metrizamide appears to be a reliable supporting diagnostic method for spinal cord atrophy.

Atrophy↗

Renal failure caused by retroperitoneal involvement of Hodgkin's disease of the lymphocyte-depletion type.

The paper presents the case of a man with non-functioning unilateral kidney due to retroperitoneal and renal lymph node involvement of Hodgkin's disease, which we interpreted as unilateral renal pelvic tumor. The disease had progressed rapidly to its termination and renal failure in addition to cachexia developed. Nephrostomy on the tumor-uninvolved side had failed to restore renal function and the patient died 3 days after surgery. The study concerns the lack of clinical entity of the nephrotic syndrome even in the absence of glomerulonephropathy often described in the literature dealing with Hodgkin's disease.

Acute Kidney Injury↗

Successful treatment of renovascular hypertension with a percutaneous transluminal angioplasty.

We report a case of typical renovascular hypertension due to right renal artery stenosis treated with percutaneous transluminal angioplasty. The followup arteriogram demonstrated merely a partial dilatation of the stenotic segment but hypertension was remarkably improved. A right-to-left ratio of plasma renin activity in the renal venous effluent decreased from 2.67:1 to 1.10:1 following treatment. Affected renal function in the previously stenotic side was ameliorated. The procedure was well tolerated by the patient and blood pressure remained normotensive during the 5 months after angioplasty.

Aged↗