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Biomedical subjects

T Morris

Publications and source records attributed to T Morris.

At least 91 records · Page 5Linked to original sources
PubMed1979

Psychological response to breast cancer: effect on outcome.

A prospective, multidisciplinary, 5-year study of 69 consecutive female patients with early (T0,1N0,1M0) breast cancer was conducted. Patients' psychological responses to the diagnosis of cancer were assessed 3 months postoperatively. These responses were related to outcome 5 years after operation. Recurrence-free survival was significantly common among patients who had initially reacted to cancer by denial or who had a fighting spirit than among patients who had responded with stoic acceptance or feelings of helplessness and hopelessness.

Attitude to Death↗
PubMed1979

Antacids and peptic ulcer--a reappraisal.

Antacids can reduce gastroduodenal acidity for long periods if taken in substantial quantities after food. Their healing effect on gastric ulcer is minimal, if present at all, and easily overwhelmed by the benefit obtained from admission to hospital. Intensive antacid therapy appears effective in healing duodenal ulcer and preventing haemorrhage from stress ulcer, and is comparable in these respects with cimetidine but with a higher incidence of side-effects. Clinical impression strongly suggests that antacids relieve pain in peptic ulcer but objective confirmation is lacking.

Aluminum Hydroxide↗
PubMed1979

Retardation of healing of large-bowel anastomoses by 5-fluorouracil.

Experiments were performed to test the hypothesis that 5-Fluorouracil (5-FU) would delay or prevent healing of large-bowel anastomoses. The caecums of 120 specific-pathogen-free rats were transected and reanastomosed at once. Daily intravenous injections of 5-FU were given to half the rats, the other half being controls and receiving an equal volume of saline. At Days 5, 7 and 10, standard-sized sections of sutire line were pulled apart, and the force required to do this was recorded. At five days the strengths of the anastomoses in the 5-FU treated animals were only 25% of that of the controls, but by ten days they were over 60% of the strength of the controls. It was concluded that 5-FU delayed, but did not prevent, healing, and that it would be safe to use it in the early postoperative period, but not until several days after operation.

Animals↗
PubMed1978

The effect of 5-fluorouracil on abdominal wound healing in rats.

We carried out experiments to test the hypothesis that 5-Fluorouracil would retard wound healing when administration was started on the day of operation. Abdominal wounds were made in rats and closed again, and some of the animals were given daily 5-FU, the rest acting as controls. Test animals were killed three, five, seven and 10 days after operation, and the strength of their wounds was measured. At five and seven days the control wounds were 10 times stronger than those of the treated animals, and at 10 days they were four times stronger. We speculated that the difference in strength might be largely due to the observed fact that the muscle layer in the treated animals was considerably weaker than in the controls. We concluded that it would be unsafe to start giving 5-FU to patients immediately after operation.

Abdominal Muscles↗
PubMed1978

Left cervical aortic arch associated with aortic aneurysm.

An aortic arch extending into the neck is a rare congenital anaomaly. Left-sided cervical aortic arch was thought to be much less common than right-sided, but they are now almost equal in incidence in the published reports. This paper describes a case of left-sided cervical aortic arch in an adult, with a previously undescribed association, aneurysm of the descending thoracic aorta. Cervical aortic arch must be considered in the differential diagnosis of pulsatile cervical swellings. The embryological development of the aortic arch is discussed. This is still controversial and it is not possible to be sure of the embryological explanation of this congenital anomaly of the aortic arch from a study of the adult anatomy.

Adult↗
PubMed1977

Psychological and social adjustment to mastectomy: a two-year follow-up study.

A consecutive series of 160 women admitted to hospital for breast tumor biopsy was assessed prior to, and at 3, 12, and 24 months following operation for marital, sexual, interpersonal and work adjustment, depression, and personality characteristics by means of rating scales based on structures interviews and standard tests. By 2 years there wery no significant differences in social adjustment between mastectomy patients and benign breast disease controls; 70% of cancer patients were no longer stressed by mastectomy at 1 year. Factors predicting poor adjustment to mastectomy were high preoperative scores on the Hamilton Rating Scale for Depression and the Neuroticism Scale of the Eysenck Personality Inventory; deterioration in sexual adjustment was associated with biological or chronological perimenopausal status. Significantly more cancer than benign disease patients were dissatisfied with the information they received about operation and diagnosis. Implications of these findings for the care of the mastectomy patient are discussed.

Breast Diseases↗
PubMed1977

Lignocaine: its effects on wound healing.

In the light of clinical observations that local anaesthetic impairs wound healing, the effect of lignocaine at various concentrations, with and without adrenaline, on the tensile strength of skin wounds in rats 3, 5 and 7 days after operation was studied. Lignocaine had an adverse effect on wound healing at 5 and 7 days, perhaps due partly to the destructive effect of the intra- and subcutaneous injection, but certainly due also to the lignocaine itself. Adrenaline potentiated this effect. It was concluded that it is better to use dilute solutions of lignocaine, preferably without adrenaline, for local anaesthesia.

Animals↗
PubMed1977

Listening levels through hearing aids: a difference of opinion.

The present authors find it impossible to compare their work with that of Powell & Tucker (Scand Audiol 5, 167, 1976) due to the lack of original data in the latter paper. The present authors papers were not written with the prime view of presenting predictive values but of reporting data on hearing aid users. The predictive value of our results has been largely and not very carefully inferred by Powell & Tucker. The predictive values of gain or output may be inferred from current research and the Powell & Tucker paper confirms the previous work rather than repudiates it. It is obvious that research workers should co-operate in using clearly stated methods and publishing original data in their papers. Furthermore it is important that the terminology used is of a standard form--or if not, that each new term is clearly defined.

Auditory Threshold↗
PubMed1977

An approach to calculating gain requirements for severely deaf children as a function of hearing loss which is independent of frequency response.

In an attempt to provide optimum listening conditions for hearing aid wearers a number of gain formulae have recently appeared in the literature. Required gains have invariably been measured at 1 kHz and expressed as a function of hearing loss. Recent research has shown that for children suffering from severe and profound deafness the 1 kHz required gain is highly dependent upon the low frequency response characteristic of the hearing aid. The present study proposes that the use of a 0.25 kHz gain formula would be advantageous with such children as it appears to be independent of the frequency response characteristic of the hearing aid.

Child↗