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Biomedical subjects

T Machida

Publications and source records attributed to T Machida.

At least 253 records · Page 14Linked to original sources

[A long-term survival after partial nephrectomy in a case of pelvic tumor arising in a solitary kidney].

A 44-year-old man was admitted on January 21, 1975 because of asymptomatic hematuria. The patient had nephrectomy of his left kidney due to nephritis at the age of three. Cystoscopy revealed no abnormalities, and excretory urography showed an irregular filling defect and slight ectasia in right upper calyx. A clinical diagnosis of pelvic tumor of the right kidney was made and partial nephrectomy was performed on April 18, 1975. The resected kidney was 4.5 X 5.0 X 6.5 cm in greatest dimension and the tumor was well localized in the upper calyx. Pathological diagnosis was transitional cell carcinoma, papillary, grade 11, stage 1. About 2 years after the operation, the patient developed a rice-sized tumor in the bladder neck followed by transurethral resection. Otherwise he is in good condition to date, 7 years and 4 months after the partial nephrectomy.

Adult

Retinal arteriolar tortuosity with macular hemorrhage.

A 58-year-old Japanese woman showed bilateral retinal arteriolar tortuosity with macular hemorrhage. Ophthalmoscopically, the retinal vein was normal, and other arteriosclerotic and hypertensive arteriolar changes were slight. The medical examination and laboratory tests did not reveal any significant etiologic factors. The hemorrhage absorbed rapidly, and visual outcome was excellent. To our knowledge, this case is the first reported in an Oriental.

Arterioles

Papillary adenocarcinoma of the rete testis: a case report.

A papillary adenocarcinoma of the rete testis in a 67-year-old man is presented. The tumor was localized in the rete testis, showing no involvement of the adjacent testicular parenchyma or the epididymis. The tumor cells manifested a transition to the normal epithelial cells of the rete testis. The electron microscopic features of this tumor are compared with those of the normal epithelial cells of the rete testis.

Adenocarcinoma, Papillary

[Renal cell carcinoma].

Forty-two cases of renal cell carcinoma with pulmonary metastasis were clinically investigated with regard to their pathological state and treatment methods. Of these 42 cases, pulmonary metastasis was noted initially in 18 cases, and in the remaining 24 cases it occurred after nephrectomy. In 20 cases (83%) pulmonary metastasis was detected within 2 years for the treatment of primary lesion. For the treatment of pulmonary metastasis, surgery was performed in 2 cases, radiotherapy in 4 cases, chemotherapy in 21 cases and hormonal therapy in 13 cases. One of the 2 patients who received surgery has survived for 7 years and 11 months, and the other for 6 months, respectively. Among the 4 cases treated by radiotherapy, a complete remission was noted in 1 case, and no improvement in 3 cases. Twenty-one cases were treated with chemotherapeutic agents. Out of these 21 cases, an objective improvement was observed in 3 cases (14%): 1 case received 3 drug combination (mitomycin C, 5-fluorouracil and cytosine arabinoside) and 2 cases received 5-fluorouracil dry syrup. Hormonal agents used were progesterone in 9 cases and testosterone in 4 cases. In the hormonal therapy group, no remission of metastatic lesions was confirmed by chest X-ray examination in 14 cases. The 1-year and 3-year survival rates were 32% and 16%, respectively. However, 4 out of 42 patients have been alive for over 5 years after the treatment for pulmonary metastasis. Therefore, even in the occurrence of pulmonary metastasis aggressive treatment including chemotherapy is preferable.

Adenocarcinoma

A study of intragastric pH in patients with peptic ulcer--with special reference to the clinical significance of basal pH value.

Determination was made of in situ gastric pH during early morning in fasting state (basal pH) by using wired glass electrodes, and results obtained were analyzed. Analysis of the pattern of variation in intragastric pH at night revealed no substantial difference between normal subjects and patients with peptic ulcer but a tendency to be lower in the latter group. It was also shown that sleeping waves appeared in the electroencephalogram in association with the increase in intragastric pH during sleep at night. The basal pH value was 5.4 +/- 2.1 in patients with gastric cancer, 3.0 +/- 2.2 in those with gastritis, 2.4 +/- 1.9 in those with gastric ulcer, 1.7 +/- 0.2 in normal subjects and 1.3 +/- 0.6 in patients with duodenal ulcer. In gastric ulcer patients more anal site of ulcer lesion was associated with lower mean age of the patients and higher incidence of intestinal metaplastic gastritis of the antral or non-metaplastic type. In patients who underwent partial gastrectomy for peptic ulcer, the pH value in the remnant stomach tended to become higher with the lapse of time in all cases, being constant at about 3 months postoperatively. The decrease in gastric acidity at 12 months after operation was incomplete in patients who underwent emergency gastrectomy for perforated duodenal ulcer but satisfactory in those who underwent selective vatotomy and anterectomy as elective operations.

Adolescent