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Biomedical subjects

T M Radda

Publications and source records attributed to T M Radda.

44 records · Page 3Linked to original sources

Acute ocular hypotony. A rare complication of temporal arteritis.

Acute ocular hypotony is a serious, but rare complication of temporal arteritis. It occurs equally often in men and women, and appears mostly in patients older than 70 years. This complication may occur in one or in both eyes. In the literature 7 cases of temporal arteritis accompanied by ocular hypotony have been reported. Hypotony probably results from a restricted production of aqueous humor caused by involvement of the arteries supplying the ciliary body. A high-dose corticoid therapy may normalize completely the intraocular pressure, and a timely treatment may preserve a satisfactory vision, since an insufficient perfusion of the optic disc does not necessarily occur. Scalp necrosis and diplopia may appear at the same time, and are a sign of multiple involvement of the arterial vessels.

Aged↗

[Occult temporal arteritis--a case report (author's transl)].

A 57-year-old female patient with ischaemic papilloedema developed vascular pseudopapillitis of the opposite eye three months later. Temporal arteritis was diagnosed by means of a biopsy of the temporal arteries. Such cases of occult temporal arteritis are characterized by the absence of typical general symptoms and pathological laboratory findings, or, alternatively, these symptoms appear only much later than the ischaemic alteration to the fundus. Hence, one should consider occult temporal arteritis when confronted with any ischaemic process of the optic nerve, and also in the case of occlusion of the central retinal artery, expecially in cases with a simultaneous rise in the blood-sedimentation rate, since high doses of steroids, when given in time, may prevent total loss of sight.

Blindness↗

[Antinuclear antibodies (ANA) in inflammatory eye diseases].

The occurrence of antinuclear antibodies was investigated in patients with chronic open-angle glaucoma, senile cataract and retinal detachment, using the indirect immunofluorescence technique. The values obtained were the same as those for a normal population. Additionally, the presence and titer levels of ANA were tested in patients with endogenous uveitis, papillitis and optic neuritis. Our results suggest that ANA do not occur more frequently in these conditions.

Antibodies, Antinuclear↗

[Branch occlusion of the central retinal artery during coronary angiography (author's transl)].

A 49-year-old man went blind in his left eye during coronary angiography. The following day an occlusion of the inferior temporal and inferior nasal branch of the central retinal artery was detected, associated with a moderate papilledema of the inferior part of the optic disk as well as retinal edema of the inferior fundus. Fluorescein angiography confirmed the clinical diagnosis, perimetry revealed loss of visual field in the superior half. Seven months after the initial examination the patient displayed a partial optic atrophy of the inferior portion of the disk associated with a moderate neovascularization in that area. The visual field loss remained unchanged.

Blindness↗

[Early results after intraocular lens implantation (author's transl)].

Within the past 12 months, 64 intraocular lenses were implanted. Only eyes close to emmetropia and not exhibiting any pathological condition were considered for this type of surgery. The average age of our patients was 76 years. Preoperative medication and surgical procedure are described. Serious postoperative complications have not been observed so far. Striate keratopathy (in 22% of the cases), as well as secondary glaucoma (in 11% of the cases) were restricted to the initial 4-5 postoperative days. In 73% of the cases the postoperative visual acuity was 6/8-6/6. Maculopathy and opacification of the posterior lens capsule left behind were responsible for reduced visual acuity in the remaining cases.

Age Factors↗

[Ocular involvement in polymyalgia rheumatica (author's transl)].

Polymyalgia rheumatica is a disease of the elderly, more common in women. Pain and stiffness localized in the proximal extremities respond well to low-dose corticosteroids. In roughly half of the cases, giant cell arteritis can be detected in apparently normal temporal arteries. There is no danger of ocular involvement in "pure" polymyalgia rheumatica, even with a positive biopsy. When cranial symptoms, such as headache or tenderness of the temporal arteries, appear, there is a great danger of ocular involvement, and high-dose corticosteroid treatment is advisable.

Adrenal Cortex Hormones↗