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Biomedical subjects

T Kozuka

Publications and source records attributed to T Kozuka.

At least 271 records · Page 15Linked to original sources
PubMed1986

Radiation necrosis of the brain and radiation-induced cerebrovasculopathy.

Thirteen patients with radiation necrosis and 6 patients with occlusive radiation-induced cerebrovasculopathy were reviewed. Computed tomography (CT) demonstrated low attenuation with a mass effect and irregular contrast enhancement in the radiation necrosis. The mass effect and the contrast enhancement decreased gradually. Angiography showed an avascular mass, generalized narrowing of the ipsilateral arteries and slow blood circulation in 3 cases. Radiation-induced vasculopathy appeared as localized stenosis and irregular walls of the arteries within the irradiated area. In cases with radiation vasculopathy accompanied by sufficient collateral blood flow brain damage was rarely demonstrated by CT. In patients with radiation-induced vasculopathy the lesion was not associated with signs of radiation necrosis.

Adult↗
PubMed1986

[Non-invasive evaluation of right ventricular pressure in children with heart diseases: quantitative assessment by thallium myocardial imaging].

201-thallium myocardial imaging studies were performed to evaluate systolic pressures in the right ventricle of 194 patients. These patients were classified to four groups. Group A (95 cases) consists of 77 patients with congenital cardiac disease, five patients with primary pulmonary hypertension, and 13 patients with history of MCLS. Congenital cardiac diseases included 30 patients with tetralogy of Fallot, 20 with ventricular septal defect, nine with atrial septal defect, and eight with pulmonary stenosis. Group B (35 cases); preoperative state of transposition of the great arteries. Group C (43 cases); post-operative state of congenital cardiac disease whose pre-operative right ventricular systolic pressures represented more than 70% of the left ventricular systolic pressures. This group included 31 patients with tetralogy of Fallot, seven with ventricular septal defect, four with atrial septal defect and one with patent ductus arteriosus. Group D (21 cases); post-operative state of transposition of the great arteries. Fifteen min after intravenous infusion of 30-50 microCi/kg 201-TlCl, myocardial images were obtained in five projections (anterior, LAO 30 degrees, 45 degrees, 60 degrees, and lateral). The angles were determined to demonstrate clearly the interventricular septum and the ventricular free wall. The images of end-diastolic phase were obtained using the ECG-synchronized gated method in each projection. The region of interest (ROI) was defined as a section or slice by drawing two lines perpendicular to the septum, and the counts of the systemic and pulmonic ventricular free wall (Cs and Cp) were analyzed to evaluate the pressure of the pulmonic ventricle. The pressures of the ventricles were obtained by cardiac catheterization performed concomitantly with the cardiac imaging.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗
PubMed1986

Functioning parathyroid cyst extending from neck to anterior mediastinum. Diagnosis by sonography and computed tomography.

A parathyroid cyst was evaluated by sonography and computed tomography (CT) in a patient with hyperparathyroidism. Sonography demonstrated a cystic lesion near the left lower pole of the thyroid, extending into the anterior mediastinum. On CT, the parathyroid cyst had a slightly high attenuation (30 H), with a smooth wall demonstrated after intravenous administration of contrast material. Fine-needle aspiration biopsy of the cyst showed elevated parathyroid hormone (PTH) level. The lesion probably represents cystic degeneration of an adenoma.

Aged↗
PubMed1985

Thallium perfusion and cardiac enzyme abnormalities in patients with familial hypertrophic cardiomyopathy.

Twelve patients of five families with familial hypertrophic cardiomyopathy were examined. Within each family, the older patients showed dilation or diminished contraction of the left ventricle by echocardiography or angiocardiography more frequently than did younger patients. LDH1 fraction (lactic dehydrogenase isoenzyme) and MB-CPK (creatinine phosphokinase isoenzyme) were increased in 7 of 10 patients. Thallium-201 myocardial scintigraphy showed perfusion defect or hypoperfusion in 9 of 10 patient. Eleven cases demonstrated remarkable hypertrophy at the macroscopic level. Marked fibrosis was observed in all 5 of the 11 patients whose histologic findings were obtained. In two necropsy cases, disarray was found throughout the right and left ventricles and the pattern of fibrosis was massive. These findings were different from those of ordinary hypertrophic cardiomyopathy. It is possible that each patient with familial hypertrophic cardiomyopathy may develop more prominent thallium and enzyme abnormalities as he becomes older, regardless of whether he develops a dilated cardiomyopathy picture.

Adolescent↗
PubMed1985

Occupational pigmented contact dermatitis from azo-dyes.

A 51-year-old man had been working in a dye factory for 25 years and had noticed itching and pigmentation on the extremities for the past 5 years. Patch testing showed positive reactions to Sudan I and Vacanceine Red, among the azo dyes which he had been handling. After he changed his work, he became free from erythematous lesions with itching. The pigmentation almost disappeared 10 months later.

Azo Compounds↗
PubMed1985

False lumens in type III aortic dissections: progress CT study.

The fate of false lumens in 13 patients having Type III aortic dissections was studied using computed tomography (CT). Contrast media filled false lumens with or without thrombosis were observed in ten patients; the false lumens of three patients were entirely thrombosed at initial examination. Follow-up CT studies showed shrinkage or disappearance of the false lumens with thrombosis in four patients, progression of thrombosis in two patients, and enlargement of the false lumen in one patient who subsequently required surgical repair. No change was observed in the remaining six patients during our observation period. CT study provides useful information for evaluating the efficacy of medical treatment and the timing of surgical intervention during follow-up evaluation of medically treated Type III aortic dissections.

Adult↗
PubMed1985

Evaluation of left ventricular function using digital subtraction angiography.

To evaluate function of the left ventricle and myocardial perfusion images, digital subtraction angiography (DSA) was performed in 45 patients with ischemic heart disease. Validity of the technique was compared with data obtained from cine left ventriculogram in all patients and 201 T1 myocardial images in 20 patients. End-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) calculated from DSA were correlated closely with those from cine left ventriculogram (r = 0.92, r = 0.94 and r = 0.86, respectively). Regional contractility at the antero-lateral wall of the left ventricle, assessed by DSA, was also correlated well with cine left ventriculogram (r = 0.75). Evaluation of the inferior wall motion showed less correlation in both procedures (r = 0.68). Phase and amplitude analysis with the same technique with radionuclide cardiac angiography was successfully applied in left ventriculogram obtained by DSA. The procedure seems to be helpful for objective evaluation of the left ventricular wall motion. Myocardial perfusion image, obtained with modified Radtke's technique, showed good coincidence with 201 T1 images. Thus, DSA is applicable for evaluation of function of the left ventricle and myocardial perfusion in patients with ischemic heart disease.

Angina Pectoris↗