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Biomedical subjects

T Koike

Publications and source records attributed to T Koike.

At least 631 records · Page 35Linked to original sources
PubMed1989

A case of atrial septal defect combined with hypertension and left ventricular hypertrophy. Left ventricular failure induced by balloon occlusion and the effect of nifedipine.

A 46 year old woman with hypertension and left ventricular hypertrophy accompanied by an atrial septal defect is reported. Hemodynamic changes induced by balloon occlusion and concomitant nifedipine were studied. Left ventricular failure appeared after balloon closure of the defect. Nifedipine decreased the increment in left ventricular end-diastolic pressure induced by balloon occlusion. After the reduction of systemic vascular resistance, the ratio of intracardiac shunt flow was still larger. Surgical closure of the defect was performed and the postoperative course was good with the use of vasodilators.

Blood Pressure↗
PubMed1989

[Reconstructive vascular surgery in the territory of the anterior cerebral artery in children with moyamoya disease].

The hemodynamics of the anterior cerebral arteries (ACAs) were studied in 28 children with moyamoya disease. In 39% of 56 cerebral hemispheres, antegrade filling of the ACAs was not verified by preoperative angiography. On the other hand, adequate collateral pathways to the ACA territory were generally not achieved by encephalomyosynangiosis (EMS) or superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis. The authors have devised new surgical methods for the revascularization of the ACA territory, which they term "encephaloarteriosynangiosis" (EAS) and "encephalogaleosynangiosis" (EGS). In these procedures, one or several burr holes are made in the frontal skull, the dura mater is incised, and either the frontal branch of the STA or the pedicled galea aponeurotica stump is placed on the surface of the frontal cortex. In addition to EMS or STA-MCA anastomosis, these methods were applied to 23 cerebral hemispheres in 14 pediatric patients. In 14 cerebral hemispheres (61%) of 10 patients, postoperative external carotid angiograms showed some cortical branches in the ACA territory, and clinical improvement was achieved in patients with transient ischemic attacks affecting the lower extremities. The results of this study demonstrate that EAS and EGS are simple and useful techniques for revascularization of the ACA territory. In addition, EGS can be applied to the territory of the posterior cerebral artery.

Adolescent↗
PubMed1989

Bilateral lenticulostriate arteriovenous malformations--case report.

A 6-year-old male with bilateral lenticulostriate arteriovenous malformations (AVMs) had suffered an intraventricular hemorrhage at the age of 10 days. Transfemoral cerebral angiography performed 6 years later revealed bilateral AVMs at the basal ganglia accompanied by vascular anomalies. Both AVMs appeared inoperable, and were treated conservatively. Bilateral, symmetrical cerebral AVMs are extremely rare, only three such cases having been reported.

Arteriovenous Malformations↗
PubMed1989

Membrane viscosity of lymphocytes and influence of phytohemagglutinin.

The membrane viscosity of peripheral blood lymphocytes (PBLs) of equine, bovine and canine was measured by the use of time-resolved fluorescence depolarization technique with 1, 6-diphenyl-1,3,5-hexatriene (DPH). The viscosity values were 0.55, 0.59 and 0.50 poise for equine, bovine and canine PBLs, respectively. These values were compared with steady-state anisotropies and order parameters measured from electron spin resonance (ESR) of 5-doxyl stearic acid. Both values were increased with increase of viscosity. The fluid property of the membranes stimulated with phytohemagglutinin-P (PHA) was measured with steady-state fluorescence anisotropy and ESR. Little change of membrane fluidity was recognized with both methods during the stimulation with PHA. It appears that PHA activation process for these lymphocytes does not included large increase of the membrane fluidity which significantly accelerate the diffusion velocity of receptors in the plasma membrane.

Animals↗
PubMed1989

Effect of the self etching dentin primers on the bonding efficacy of a dentin adhesive.

The efficacy of marketed and experimental self etching dentin primers which contained dicarboxylic acids or their esterified salts diluted in 35% hydroxyethylmethacrylate (HEMA) solution were studied by measuring the wall-to-wall polymerization contraction of the light curing composite in the cylindrical dentin cavity and the tensile bond strength to the flat dentin surface. In both of the measurements, a marketed dentin bonding agent and resin monomer was applied after the treatment with experimental primers and a marketed primer, respectively. It was revealed that two experimental primers composed of the methacryloxyethyl-succinate or methacryloxyethyl-phthalate and HEMA, exhibited a remarkable effect on the bonding efficacy of a dentin adhesive employed in this study. A marketed primer which contained maleic acid and HEMA could not improve the bonding between the resin and dentin cavity wall although a significantly high bonding strength (11.9 +/- 5.7 MPa) was obtained after 24 hours.

Acid Etching, Dental↗
PubMed1989

[A device to display moving objects for visual stimulation in the early development: with numerical control of a pulse motor].

In order to observe oculomotor responses to moving objects in infants and the profoundly retarded, a control system of moving objects was developed. The system consists of two parts, the one is to control movement, while the other is to display stimuli. The movement control part is made of a microcomputer, a pulse motor, and a rail, which guides a stimulus carrier with slight friction. The pulse motor rotates 1.8 degrees, according to the input of one pulse. Therefore, the microcomputer can control the velocity of movement of a heavy object exactly. The microcomputer detects the position of a stimulus carrier, counting the number of pulses and receiving signals from switches attached to the rail. The stimuli displaying part controls lighting with respect to the position of a stimulus carrier. Applying this system to a profoundly retarded subject, whose DA was three months, smooth pursuit oculomotor responses at the same velocity as the stimulus were observed in EOG recordings. Measurement of duration of those responses was achieved.

Adult↗
PubMed1989

[A study of aphasia caused by putaminal hemorrhage].

Aphasia was evaluated in 21 right-handed patients (39-74 years old) with putaminal hemorrhage, and compared with that caused by thalamic hemorrhage. The patients were divided into three groups by the volume of the hematoma: small hematoma (I, n = 6), middle hematoma (II, n = 8) and large hematoma (III, n = 7) groups in computed tomographic findings. Aphasia examination was performed 8-37 days (mean 21 days) after the onset. In group I, aphasia was not seen or just transient, if any. In group II, aphasia was mainly a mixed type, and the prognosis was excellent in many patients. In group III there were expressive type at anterior lesion, receptive type at posterior lesion and global aphasia at anterior-posterior lesion, and the prognosis was not good. It is suggested that the putamen itself does not participate in language behavior, and that aphasia caused by putaminal hemorrhage is due to destruction of the surrounding tissue of the putamen. The type of aphasia and prognosis are varied by the site of a lesion and a hematoma volume. It is also suggested that the thalamus is related to language behavior in a circle of thalamus-cortical language area-thalamus. Aphasia caused by putaminal or thalamic hemorrhage was observed to be different from classical cortical aphasia. But there was no significant difference between aphasia caused by putaminal lesions and that by thalamic lesions.

Adult↗
PubMed1989

Murine leukaemia virus gene product as an acute phase protein: complete suppression of serum gp70 synthesis in hepatocytes of B10.S mice.

The Sgp-1c trait is associated with H-2s and relates to the small content of serum gp70 as well as the lack of serum gp70 responsiveness to lipopolysaccharide (LPS). Northern hybridization of RNA from B10.S liver and its hybrid with NZB showed that the suppression of gp70 in Sgp-1c carrying mice can be regulated at the transcriptional level. However, the inheritance of this trait shows the complicated manner of segregation in certain crosses. All (B10.S x NZB) F1 hybrid mice and F1 x B10.S back-cross mice had low amounts of serum gp70 and did not respond to LPS with increased levels of serum gp70. In contrast, F1 x NZB back-cross progeny varied widely in serum gp70 levels. The serum gp70 levels of most F1 x NZB back-cross mice was increased by LPS, although the range of increases was broad. These results indicate that the Sgp-1c alone is not sufficient to lower serum gp70 levels, unless B10 background is present. The expression of Sgp-1 system, which is linked with the H-2 region, requires non-H-2-linked genes.

Acute-Phase Proteins↗
PubMed1989

[A case of sigmoid carcinoma successfully treated with endoscopic topical infusion of OK-432 and UFT oral treatment].

A 78-year-old man had a tumor of Borrmann type II affecting about one third the circumference of sigmoid colon, which was diagnosed as well-differentiated adenocarcinoma from biopsy. Although surgical intervention was recommended and the radical operation seemed possible from preoperative examination, the patient first refused it. Of necessity, systemic administration (s.c) and single endoscopic topical infusion of OK-432 and oral treatment of UFT were performed for 1 month. Since the patient agreed to receive an operation later, sigmoidectomy and lymph node dissection (R 2) were performed, resulting in the disappearance of tumor cells histologically. One week before endoscopic infusion, oral UFT and subcutaneous OK-432 were initiated. Although no macroscopic change was found during the topical infusion as compared with the time of first examination, the bulging disappeared, showing a polypoid change and IIc-like findings after 3 weeks. The operation was performed after an additional week, after which a benign tumor was found macroscopically and the disappearance of tumor cells histologically. Although many reports have dealt with the effect of endoscopic treatment for gastric carcinoma, there have been fewer reports describing the endoscopic treatment performed in patients with colon carcinoma, making it difficult to evaluate its therapeutic effect. However, this endoscopic therapy was suggested to be capable of becoming a useful treatment for inoperable colon carcinoma from the present case, whereas chemotherapy was found to have almost no effect on colon carcinoma in general.

Adenocarcinoma↗
PubMed1989

[Fechtner syndrome: report of two families and review of the literature on the related disorders].

Two families who had been reported as having May-Hegglin anomaly were diagnosed as having Fechtner syndrome based on complication of renal disease, deafness and characteristic leukocyte inclusions. By Wright-Giemsa staining, the inclusions of neutrophils were smaller and stained less clearly than those seen in May-Hegglin anomaly. Ultrastructurally, the inclusions consisted of organelle-poor cytoplasm, containing small particles, which were probably ribosomes. Some inclusions contained only a few filaments or small remnants of rough endoplasmic reticulum (RER). The latter resembled the findings observed in Fechtner syndrome. They lacked the parallel arrays of filaments characteristic of May-Hegglin anomaly and the parallel strands of RER seen in toxic Döhle bodies. Renal disorders ranged from microscopic hematuria to renal failure requiring dialysis in one family and persistent proteinuria in the other family. Deafness was sensorineural type or combined type due to otitis media. Except for the fact that they lacked congenital cataracta, the findings in these two families were consistent with those in Fechtner syndrome.

Adult↗
PubMed1989

[Pulmonary complication after resection of lung cancer--difficulty in expectoration and cough dynamics].

From January 1975 to December 1986, 415 patients were operated for primary lung cancer. Postoperative pulmonary complications were observed in 83 patients and among them 48 patients (57.8%) suffered from difficulty in expectoration. Postoperative expectoration mostly depends on the ability of coughing. To evaluate cough dynamics, expiratory flow-rate and volume at voluntary maximal cough were measured. The more expiratory flow rate and volume a cough has, the more effective it is for expectoration. In those patients with decreased FEV1.0, or respiratory muscle weakness because of emaciation and aging, or severe pain in the wound, the cough dynamics was decreased. By cleaning retained secretions in the respiratory tract, postoperative pulmonary complications would be prevented. However in cases where the decrease in postoperative cough dynamics is predictable, application of limited resection should be considered as well.

Aged↗
PubMed1989

[Liquid embolization for arteriovenous malformation with temporary balloon occlusion of another feeders].

A case of frontal arteriovenous malformation, embolized using a new balloon catheter technique, was reported. During liquid embolization of the main feeder from anterior cerebral artery, middle cerebral artery was temporary occluded with another balloon catheter, to decrease blood flow from branches of middle cerebral artery. About 90% of the AVM could be obliterated by this technique.

Adult↗
PubMed1989

[Measurement of superior thyroid artery dynamics in cases of solitary thyroid tumor and its clinical evaluation].

Thyroid blood flow related with thyroid function is of great importance in diagnosing thyroid gland disease. However, there has no report on such observations of thyroid blood flow dynamics, especially non-invasively and quantitatively. In this study new developed ultrasound duplex scanning system was used to measure the superior thyroid blood flow and analyze the hemodynamics in 105 cases of solitary thyroid tumors, including 30 cases of thyroid cancers. Superior thyroid blood flows on afferent portion obviously increased both in benign and malignant tumor cases, but clear difference between them could not be found. On the other hand, in concern with the blood flows on inafferent portions, malignant thyroid tumor cases showed remarkable increase with statistical difference. The blood flow ratio between afferent and inafferent portions was considered to distinguish between benign and malignant thyroid tumors as quantitative criteria. The assumption that the tumors whose blood flow rate was below 3.0 is malignant led the fine result that accuracy was 79.8%, sensitivity; 71.5%, specificity; 81.5%. This quantitative criterion requires no surgical technique, therefore, this is useful for the tissue characterization of thyroid tumors.

Adult↗
PubMed1989

[Somatosensory evoked potentials over the unaffected hemisphere in patients with unilateral intracerebral hematoma].

Somatosensory evoked potentials (SEPs) recorded from the unaffected hemispheres were studied in patients of less than one month after the onset of unilateral intracerebral hematoma. We examined 66 SEPs obtained from 49 patients with putaminal hemorrhage (midline shift 0-15 mm), 38 SEPs from 25 patients with thalamic hemorrhage (midline shift 0-8 mm), and 14 SEPs from 10 patients with subcortical hemorrhage (midline shift 0-12 mm). These examinations were made after electrical stimulation of the median nerve at the wrist by using square waves of 0.2 msec in duration delivered at a rate of 3 Hz. We analyzed the first cortical potential N 20 recorded from the contralateral scalp over the unaffected hemisphere with reference on Fpz. N 20 peak latency was compared with the maximum shift of the midline structure such as in foramen of Monro or third ventricle in computed tomogram. Also with the site of the hematoma and the disturbance of consciousness. N 20 peak latency was not correlated with the degree of the midline shift in all the patients. There was abnormal prolongation of N 20 peak latency in one SEP of one patient, and disappearance of N 20 in two SEPs of two patients with putaminal hemorrhage. Abnormal prolongation of N 20 peak latency was found in 3 SEPs of 3 patients with thalamic hemorrhage. There was no disappearance of N 20 in patients with thalamic hemorrhage. There was no abnormal prolongation or disappearance of N 20 peak latency in patients with subcortical hemorrhage. In two of five patients showing stuporous state, disappearance of N 20 was found.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1989

[A case of congenital diaphragmatic hernia due to left central tendon defect in pregnancy].

A twenty-seven-year-old 25 weeks gestation female was admitted with recurrent symptoms of nausea, vomiting and epigastric pain. She was diagnosed as left diaphragmatic hernia by chest X-ray film, CT and esophago-gastrography. During operation, a left central tendon defect was observed, and was 3.5 cm in diameter. The margin of the defect was smooth and round. It was associated with diaphragmatic eventration. The small intestine and transverse colon were herniated into the left thoracic cavity. The central tendon defect was closed with direct mattress sutures and was reinforced by overlap-technique of the diaphragm. To our knowledge, this type of defect has not been described previously in Japan. Diaphragmatic hernia in pregnancy is very rare, and presents abdominal pain, vomiting and dyspnea. Usually the diagnosis is achieved by chest X-ray film. However, esophago-gastrography should be added, if the diagnosis could not be confirmed by chest X-ray film. Conservative management is reported to bring high mortality, therefore, prompt surgical repair is advisable.

Adult↗