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Biomedical subjects

T Kitamura

Publications and source records attributed to T Kitamura.

At least 757 records · Page 42Linked to original sources
PubMed1983

A histopathologic study of benign and malignant lymphoepithelial lesions of the parotid gland.

Twenty-three cases of benign and malignant lymphoepithelial lesions without Sjögren's syndrome were examined: 21 were classical benign lymphoepithelial lesions, and were mostly found in males older than 50 years of age. The other two cases were identified as undifferentiated carcinoma arising from benign lymphoepithelial lesion (8.7%; 2/23). Histologically, this carcinoma is characterized by the formation of cell nests of variable size and by marked lymphoplasmacytic infiltrations into the stromal tissue. In immunofluorescence, an increase of plasma cells containing IgA and IgG was noted in the marginal areas of carcinoma cell clusters. Electron microscopy disclosed that the carcinoma was composed of poorly differentiated cells with occasional squamous differentiation. No dysplastic characteristics were found in the infiltrating lymphocytic components. These two cases of carcinoma were found in middle-aged females.

Adult↗
PubMed1983

Time estimation and time production in depressive patients.

Twenty-three depressive inpatients and matched controls were studied three times at 2-week intervals. Both patients and controls initially overestimated, and subsequently approximated to, the "short" time spans (5-240 sec) whilst both correctly estimated the "long" ones (15 and 30 min) over the three occasions (Time Estimation Test, TET). There were no differences in the TET scores among the patients themselves, or between the patients and controls with the exception of one time span which the patients overestimated more than the controls. Among the depressive symptoms, only retardation was correlated with the TET scores. Similarly in the production of 30 sec (Time Production Test, TPT) there were no differences among the patients or between patients and controls. Again, only retardation was negatively correlated with the TPT score. Since the TET scores of the "short" time spans were negatively correlated with the TPT scores, it was speculated that both results derived from a single faculty, which was clinically manifested as retardation.

Adult↗
PubMed1983

Blink rate in psychiatric illness.

Twenty-three patients diagnosed as depressed and a matched group of normal subjects were interviewed on three occasions using standardised procedures. Their behaviour was quantified from video recordings. The results indicate that blink rate is increased in depression and falls to normal levels during treatment. The effect on blink rate was found to be independent of medication, but was related to the degree of improvement in the patients' condition. By contrast a sample of schizophrenic patients seen on one occasion showed a reduced blink rate which was probably a result of neuroleptic administration.

Blinking↗
PubMed1983

Hepatocellular carcinoma: sonographic and histologic correlation.

Sonographic and histologic correlation was studied in 20 cases with a combined total of 23 resected lesions of hepatocellular carcinoma. All cases were examined by sonography within 1 week before surgery. Tumor sonograms were classified as hypoechoic, complex, or hyperechoic on the basis of the difference in echogenicity between the lesion and the surrounding liver parenchyma. Fourteen excised pathologic specimens were examined after surgery by a fixed-position sectional sonographic technique that permitted detailed comparison of the sonograms with the histologic findings. Each of the three types of lesion classified by echo pattern exhibited specific histopathologic characteristics. The hypoechoic lesion corresponded to a solid tumor without necrosis; the complex lesion corresponded to a tumor with partial necrosis; and the hyperechoic lesion was represented histopathologically by two distinct types of tumor, one with fatty metamorphosis and the other with marked sinusoidal dilatation. Fixed-position sectional sonography is a useful technique for comparing histologic and sonographic findings in a given tissue section and it contributes to the investigation of tissue characterization by sonography.

Adult↗
PubMed1983

Isolation of virus causing hemorrhagic fever with renal syndrome (HFRS) through a cell culture system.

Twenty-three rat lung specimens collected in outbreaks of hemorrhagic fever with renal syndrome (HFRS) in three medical institutions were inoculated onto the VERO-E6 cell monolayers. After several blind passages, an agent growing serially in the cell cultures and reacting specifically with known HFRS-positive sera was isolated from two of these specimens. The two isolates were antigenically identical each other. The agent, named strain SR-11, was identified as the causative virus of HFRS by its antigenic identity with E6 cell-adapted HFRS virus, Hantaan 76-118 strain, and the specific reactions with sera from various HFRS cases.

Adolescent↗
PubMed1983

[Postprandial plasma secretin concentration and luminal pH in patients with gastrectomy].

The plasma secretin concentration in response to a meat meal and luminal pH were investigated in patients with gastrectomy: total gastrectomy with Roux-Y anastomosis or interposed jejunal anastomosis and partial gastrectomy with Billroth I or Billroth II anastomosis. The fasting plasma secretin concentration was significantly elevated in relation to the decreases of duodenal pH in postprandial state in normal subjects. No significant response of the plasma secretin and jejunal pH were observed in patients with total gastrectomy with Roux-Y anastomosis, however total gastrectomized patients with jejunal interposition showed the peak plasma secretin response in postprandial state. In patients with Billroth I the postprandial plasma secretin concentrations were well responded when the duodenal pH was below 4.5, however it was less than that of normal subjects. In patients with Billroth II the response of plasma secretin was much less than that of Billroth I, even though the decrease of jejunal pH was as comparable as in Billroth I. These studies suggest that a Billroth I operation after subtotal gastrectomy and interposed jejunal anastomosis after total gastrectomy are better procedures than the Billroth II or Roux-Y anastomoses to obtain endogenous secretin release.

Adult↗
PubMed1983

[Experience with transabdominal and scrotal ultrasonographic examination in urology].

To evaluate its diagnostic availability in urology, transabdominal and scrotal ultrasonographic examination was made on 87 patients who had been admitted to our hospital for space occupying lesions. In retroperitoneal lesions, adrenal tumors and renal tumors greater than 2.5 cm could be detected by this examination. In pelvic lesions, bladder tumors greater than 0.5 cm were demonstrated and prostatic carcinoma with heterogeneous echotexture and irregular margin was discriminated from BPH. Not only could fluid-filled scrotal lesions larger than 1.0 cm be distinguished from solid mass lesions, but the intrascrotal anatomy could also be demonstrated in detail. Because of its safety, flexibility, and accuracy in detecting space occupying lesions, this examination could be a useful screening test in urology. Representative cases we experienced are presented.

Abdomen↗
PubMed1983

Postprandial plasma secretin response in patients following gastrectomy.

Endogenous secretin release and luminal pH changes after a test meal were investigated in five normal persons and in 22 patients after gastrectomy and various anatomic reconstructions, such as Billroth I and II anastomoses after subtotal gastrectomy and Roux-en-Y and interposed jejunal anastomosis after total gastrectomy. In patients in the Billroth I group, the response of postprandial secretin was good if the duodenal pH was below 4.5 but it was less than that of normal persons. After the Billroth II operation, even when the jejunal pH was below 4.0, the response was much less than that for the Billroth I group. After the complete abolishment of gastric acid secretion by total gastrectomy, no postprandial secretin response was noted in patients with the Roux-en-Y anastomosis. However, a response was seen in patients with interposed jejunal anastomosis, even though it was less than that for those in the Billroth I group and in normal persons. We conclude that the impairment of endogenous secretin release may be an important factor in pancreatic dysfunction after gastrectomy, and we suggest that a Billroth I operation after subtotal gastrectomy and interposed jejunal anastomosis after total gastrectomy are better procedures than the Billroth II or Roux-en-Y anastomoses to obtain endogenous secretin release.

Duodenum↗
PubMed1983

[Predictive value of acute phase reactants (APR)-score for perinatal infections].

For the early diagnosis of antepartum and intrapartum bacterial infection, we compared the predictive value of the APR-Score using C-reactive protein (CRP), Orosomucoid (Om) and Haptoglobin (Hp) in cord sera and neonatal blood samples, with the combination of many different screening techniques such as cord blood culturing, the determination of cord serum IgM and IgA, neonatal gastric aspirate culturing, polymorphonuclear leucocytes counting in gastric aspirate, and histological examination of cord. We found that among these screening techniques the APR-Score correlated best with the presence of infection. Sixty three per cent of clinically infected neonates were well diagnosed with cord blood APR scoring, and the APR-Score of all infected neonates had exceeded 1 point within the following 3 days. This study supports the theory that an elevated APR-Score can aid effectively in the early diagnosis of perinatal bacterial infection in the newborn infant.

Bacterial Infections↗