Search PubMed⌕ Search

Biomedical subjects

T Katsumata

Publications and source records attributed to T Katsumata.

At least 163 records · Page 9Linked to original sources

The usefulness of urinalysis reagent strips in selecting Schistosoma haematobium egg positives before and after treatment with praziquantel.

The effectiveness of urinalysis reagent strips for haematuria and proteinuria in selecting Schistosoma haematobium egg-positive persons was studied on 426 subjects of all ages in a Kenyan community before and 3 months after treatment with praziquantel. Before and after treatment, the degree of urinary blood or protein and prevalence of egg positives were closely associated. Haematuria and proteinuria were positively correlated with urinary egg counts. For selecting egg-positive persons with reagent strips, a combined criterion 'haematuria trace up or proteinuria 1 + up' was considered the best in this area. With this criterion, sensitivity and specificity before treatment were 69.6 and 84.4 respectively. These values remained at the same level (70.7 and 81.2%) even after treatment with praziquantel reduced prevalence from 59.4 to 13.6% (77% reduction) and intensity of infection from 57.2 to 11.3 eggs 10 ml-1 of urine (80% reduction). Although the sensitivity was not very high, heavy infections were not missed. If all those selected with reagent strips were treated and cured, a 98% reduction in total egg excretion by the community would be expected in both our first and second urine examinations.

Adolescent↗

[Ulcerative colitis and pregnancy].

The relationship between ulcerative colitis (UC) and pregnancy was studied in 83 cases (124 deliveries). The results were as follows: 1) In women with UC, there was no significant difference in fertility compared with the general population. 2) The existence of UC and treatment of UC during pregnant period had no significant adverse effects for the course of pregnancy. 3) In the 17 out of 36 pregnancies with inactive UC at the onset of pregnancy suffered relapses. Relapse rate in same patients in the pregnant period was significant higher than that in the non-pregnant period. 4) First attack of UC developing in 12 cases during pregnancies or the puerperium, the onset being commonly in the first trimester. UC developing during pregnancy was especially severe in other patients. We concluded that the relapse rate of UC is high during pregnant period, however, the course of pregnancy is not affected with UC.

Colitis, Ulcerative↗

[A case of Klinefelter's syndrome with acute mitral regurgitation caused by idiopathic chordal rupture].

It has been reported that the incidence of mitral valve prolapse was remarkably increased in patients with Klinefelter's syndrome. Some cases which have been previously reported were associated with hemodynamically significant transvalvular regurgitation, however, none of them underwent a surgical treatment such as valvular replacement. Here we report a case of Klinefelter's syndrome which underwent MVR for mitral regurgitation caused by idiopathic chordal rupture. Pathological microscopic examination showed topical and minor myxomatous changes on the free edge of the leaflet and no inflammatory changes such as in infectious endocarditis. It is, therefore, suggested that an echocardiographic follow-up should be carried out in case of Klinefelter's syndrome during its life and also in the case treated by a prophylactic therapy for endocarditis with antibiotics. And when, unfortunately, surgical treatment is required, valve replacement would be preferable to valvuloplasty because of a fragility of leaflet.

Chordae Tendineae↗

Clinical application of a static splitting agent for removing the denture from its cast after curing.

A very effective method for removing a denture from its cast after curing has been developed using a static expansive agent for hydration. Three filling hole designs for packing the expansive agent into a stone cast were examined to obtain the most effective method of splitting the cast for clinical application. The dynamic strain in the resin denture base was measured during static splitting one filling hole design was the safest for handling and the most effective for removing the denture. The upper tolerance limits for the maximum strain were estimated to be 2.9 x 10(-3) in the upper denture and 3.4 x 10(-3) in the lower denture. These values were lower than one-third of the critical strain corresponding to the proportional limit of the denture resin.

Calcium↗

The effect of a palatal resin plate on consonant articulation.

This is the introductory paper of the forthcoming series of papers on the articulation of the Japanese consonants with a full denture and denture plate. The purpose of this research is to examine how the insertion of a full denture and denture plate affects the articulation of the Japanese consonants by comparing the articulation with and without it. The material for the experiment are thirty groups of Japanese words and phrases that are uttered by normal native speakers of Japanese with and without the insertion of a full denture and denture plate. Each of the thirty groups of Japanese words and phrases contains a Japanese consonant to be examined. The phonetic apparatus used are the sound spectrograph, oscillograph, phono-laryngograph, flow-nasalitygraph, etc. The aim of this research is to examine how the insertion of a full denture and denture plate affects the articulation of the Japanese consonants by means of comparing the articulation with and without it. Introduced below are three tables of Japanese consonants/syllables presented by other scholars in Japan. Table 1 is quoted from Bunkacho (The Agency of Cultural Affairs, Japan) (1983). Table 2 is quoted from Kindaichi (1988). Table 3 is quoted from M. Onishi (1984).

Denture, Complete, Upper↗

[A case of aneurysm of the inferior left ventricular wall].

Aneurysms of the inferior left ventricular wall represent only a small fraction of all aneurysms that have been reported in surgical series. And in comparison to anterior left ventricular aneurysms, a comparatively higher percentage of reported inferior wall aneurysms was classified as false. A 73-year-old male was admitted for acute inferior myocardial infarction. Three weeks after admission, cardiac catheterization was carried out. Coronary arteriography revealed triple vessel disease and left ventriculography showed an aneurysm of the inferior left ventricular wall, whose feature near the mitral annulus was multiple fenestrations. Left ventricular aneurysmectomy and aortocoronary bypass grafting to the left anterior descending artery were simultaneously performed under cardiopulmonary bypass with moderate hypothermia. The pathological feature was a true aneurysm. The postoperative course was uneventful.

Aged↗

[Iatrogenic left main coronary artery stenosis following aortic valve replacement: two cases report].

Two cases of iatrogenic left main coronary artery stenosis (ICOS) following aortic valve replacement (AVR) are documented. The first patient began to have chest pain due to myocardial ischemia 7 months after AVR. Angiographically, the ostium of her left coronary artery was severely stenotic. She refused coronary bypass grafting. She died of myocardial infarction due to ICOS, 23 months after AVR. Histologically, a loose cellular connective tissue was found around the stenotic coronary arterial lumen. The other patient had chest pain 4 months after aortic and mitral valve replacement. The ICOS was diagnosed angiographically. After she had coronary bypass grafting, she was free from myocardial ischemic symptoms. The onset of myocardial ischemic symptoms in the first six months after AVR is highly suggestive of ICOS, and urgent coronary angiography is recommended and, if proximal stenosis of the coronary arteries is diagnosed, coronary bypass grafting should be performed.

Adult↗

[A case of cerebral arterial ectasia accompanied by intraventricular hemorrhage].

A case of cerebral arterial ectasia is reported. A sixty-one year old male revealed sudden disturbance of consciousness. CT examinations disclosed massive intraventricular hemorrhage and the cerebral angiograms showed remarkable elongation and dilatation of cerebral arteries. The authors discuss cerebral arterial ectasia from a clinico-pathological point of view.

Cerebral Arterial Diseases↗

Hatching of Schistosoma mansoni eggs is a Ca2+/calmodulin-dependent process.

The effect of calcium channel blockers (diltiazem and verapamil) and a calmodulin antagonist (W-7) on the hatching of Schistosoma mansoni eggs in fresh water was studied. The hatching of the eggs was inhibited by diltiazem and W-7 in a dose-dependent fashion and only slightly by verapamil. The present study indicates that the hatching of S. mansoni eggs is a Ca2+/calmodulin-dependent process.

Animals↗

Fallout 3H in human tissue at Akita, Japan.

The 3H concentration in Japanese human tissue samples is reported in this paper. Four brain, 10 liver, and nine lung samples from 11 cases were collected from Akita Prefecture in northern Japan from January to July 1986. The median of free-water 3H concentration was similar in these tissues and agreed well with the concentrations in the diet, including tap water. The median specific activity ratio of tissue-bound 3H to free-water 3H was 1.1 and was slightly lower than that in the diet. The specific activity ratio was also lower than that reported in the United States and significantly lower than in Italy.

Brain Chemistry↗

Further study on fallout 3H ingestion in Akita, Japan.

To study fallout 3H ingestion in Japan, 16 separate food-group samples were collected from Akita City in northern Japan during early summer and late autumn in 1986. Furthermore, total diet samples which are duplicate composite food samples consumed by five or six persons for a period of 1 d were also obtained in Akita City. The 3H concentration in free water and that in a tissue-bound form were determined separately. Seasonal changes of 3H concentration in the food samples and the total diet samples were not found clearly. The average 3H concentration in the free water including tap water was 1.6 Bq L-1. The mean ratio of specific activity of tissue-bound 3H to that of 3H in free water was found to be 1.2. The average total 3H ingestion was estimated to be 4.0 Bq d-1, while the proportion of tissue-bound form 3H ingestion to total 3H ingestion was 11%. Cereal was the greatest contributing food group to ingestion of tissue-bound 3H. These findings were consistent with our previous results for food samples collected in 1985.

Food Contamination, Radioactive↗

Differential requirements of gag and gamma-actin domains for transforming potential of Gardner-Rasheed feline sarcoma virus.

The oncogene of Gardner-Rasheed feline sarcoma virus (GR-FeSV) encodes the 70-kilodalton protein containing gag(p15), gamma-actin, and fgr domains. To determine the role of these domains in the biological activity of P70gag-actin-fgr, we have constructed in-frame deletion and insertion mutants of GR-FeSV. We found, first, that the gamma-actin region could be deleted without affecting the transforming ability of these constructs, although an insertion mutant in the middle of the gamma-actin domain (map position 671) was partially defective in transformation and specifically had a reduced level of in vitro autophosphorylation activity. Second, mutations affecting the C-terminal third of the gag region appeared to abolish the ability to transform NIH 3T3 cells and autophosphorylation activity. These results suggest that the gamma-actin domain is not essentially required for the transforming activity of GR-FeSV but that it may take part in maintaining the conformational integrity of P70gag-actin-fgr and that the gag(p15) domain might have a critical role in modulating the function of P70gag-actin-fgr.

Actins↗

Japanese consonants compared with English with regard to prosthodontic dentistry.

This is the introductory paper of the forthcoming series of papers on Japanese consonants compared with English, presented as a basic study for prosthodontic dentistry. Materials for our experiment are fifteen groups of Japanese and English words and phrases to be uttered by normal native speakers of Japanese and English respectively. They are speakers of a modified standard Japanese and the Hichiku (: part of northern Kyushu) accent of Japanese and those of standard British English, General American English and Eastern American English. Each of the fifteen groups of words and phrases contains a set of Japanese and English consonants to be examined and compared with each other. The phonetic apparatus to be used are the sound spectrograph, oscillograph, phono-laryngograph, flow-nasalitygraph, electro-palatograph, etc.

Dentures↗

Ossification of the ligamentum flavum. A case report and its MRI finding.

A case of thoracic myelopathy due to ossification of the ligamentum flavum is presented. A fifty-five year old female complained of sensory and motor disturbance of lower limbs. Neuroradiologically, in addition to ossification of the posterior longitudinal ligament throughout the spines, ossified ligamenta flava were found at the Th10-11 level and magnetic resonance imaging (MRI) clearly showed the spinal cord compressed at the same level by a low-intensity-signal lesion. Laminectomy and removal of the ossfied ligamenta flava improved her neurological dysfunction. The usefulness of the MRI in the neuroradiological diagnosis was confirmed.

Female↗