Search PubMed⌕ Search

Biomedical subjects

T Kamata

Publications and source records attributed to T Kamata.

At least 253 records · Page 14Linked to original sources
PubMed1977

Solvolytic desulfation of glycosaminoglycuronan sulfates with dimethyl sulfoxide containing water or methanol.

A solvolytic desulfation of glycosaminoglycuronan sulfates was developed by treatment of their pyridinium salts with dimethyl sulfoxide containing 10% of water or methanol at 80-100 degrees. Chemical and physical studies showed that the solvolytic desulfation is a useful method applicable to all the known glycosaminoglycuronan sulfates without producing depolymerization or unfavorable chemical changes in the polysaccharide molecules. An almost completely desulfated, N-acetylated heparin (S: 0.12%) was obtained by treatment of an N-desulfated and N-acetylated heparin with dimethyl sulfoxide containing 10% of methanol for 2 h at 100 degrees.

Dimethyl Sulfoxide↗
PubMed1977

[Clinical experience with sustained release cefalexin (S-6436) in surgery (author's transl)].

Sustained release cephalexin (S-6436) was studied in 23 outpatients (20 males, 3 females) who visited surgery of our hospital. The summary of the study is as follows: 1) The drug was administered for 2 approximately 8 days and the average was 3.5 days. Clinical effectiveness was 87.0% with the following breakdown: excellent 4, good 16, and poor 3. 2) Causative organisms isolated from the patients showing excellent effectiveness were all staphylococci. 3) No side effects were observed in any patients receiving the drug. From the above results, it is expected that S-6436 has good effectiveness and can be used as a first choice drug to outpatients with mild infections such as superficial infections who want to go to the office or school over their receiving the treatment.

Adolescent↗