Search PubMed⌕ Search

Biomedical subjects

T Kakegawa

Publications and source records attributed to T Kakegawa.

At least 235 records · Page 13Linked to original sources

Preoperative radioactive therapy for esophageal carcinoma. Randomized evaluation trial in eight institutions.

A cooperative, prospective, randomized study to evaluate the effectiveness of preoperative irradiation in curatively resected esophageal carcinoma was performed in 364 cases in eight institutions from August 1982 to November, 1983. Based on the survival curves, postoperative irradiation alone was superior to preoperative plus postoperative irradiation. Because of the progression of the disease and complications after operation, there were many inevaluable cases in this study. However, analysis revealed there was no bias caused by a greater number of unfavorable patients being selectively included in inevaluable cases in the postoperative irradiation only group. Our data question the value of preoperative irradiation being performed in addition to resection plus postoperative irradiation.

Carcinoma↗

[Improved treatment of thoracic esophageal cancer based on a retrospective study of recurrence following resection].

Recurrence after resection of thoracic esophageal cancer was classified according to site of recurrence into 5 categories; 1) local recurrence, 2) recurrence at the anastomotic site, 3) recurrence in cervical or mediastinal lymph nodes, 4) recurrence in abdominal lymph nodes and 5) distant organ metastasis. Although the combined resection of the trachea or aorta was performed in several cases with local extension, its clinical results were not superior to those from palliative resection. To prevent recurrence at the anastomotic site, we performed either pharyngeal anastomosis with laryngectomy or esophageal anastomosis just below the larynx. However, such anastomosis just below the larynx was liable to cause aspiration pneumonia. To prevent lymph node recurrence in the neck or mediastinum, we performed cervical and mediastinal lymph node dissection. However, lymph node recurrence in the upper mediastinum of the left side was occasionally observed in case receiving this operation, with lymph node recurrence being decreased by postoperative irradiation, though prognosis was not always improved. Anti-cancer agents CDDP and VDS or 5Fu were effective. To prevent abdominal lymph node recurrence, we recommend that abdominal lymph node dissection is necessarily performed as for cardiac cancer. To prevent distant organ metastasis, we recommend anti-cancer therapy following radical lymph node dissection.

Esophageal Neoplasms↗

[A case of squamous cell carcinoma of the breast].

A case of squamous cell breast carcinoma is presented. The patient was 31-year old woman with a complaint of a right breast mass. The tumor was found to measure 7.0 x 8.0 cm without any inflammatory signs, and was associated with a bloody nipple discharge. Lymph-node metastases of the ipsilateral axillary and supraclavicular nodes were noted, and metastasis to the fifth lumbar vertebrae also was seen. Because of a diagnosis graded T4bN3M1, stage IV, an extended radical mastectomy was performed. Histologically, the major portion of this tumor consisted of a squamous cell carcinoma with a minimal component of adenocarcinoma and accompanying keratinization. The patient died of this cancer 5 months after the operation.

Adult↗

Intrathoracic application of the latissimus dorsi muscle for esophageal cancer operation.

In order to reinforce the difficult closure of the bronchial stump, or esophageal anastomosis, a pedicle flap, taken from the latissimus dorsi muscle, was applied to 7 patients with tracheal repairs, and 11 patients with extensively dissected areas, at the time of esophageal cancer surgery. Utilizing this technique, the complications associated with extended esophagectomy could be minimized. Intrathoracic application of the latissimus dorsi muscle flap is a useful method of supporting extended esophagectomy for esophageal cancer.

Esophageal Neoplasms↗

Safe jugular and subclavian venipuncture under ultrasonographic guidance.

Although jugular and subclavian venipuncture is a valuable technique and frequently utilized, blind venipuncture is at times associated with complications such as arterial puncture, pneumothorax, and malpositioning of catheters. We performed venipuncture under the guidance of high-resolution real-time ultrasonography, and these catheter-related complications were prevented. Jugular, subclavian and innominate veins and arteries, the pleura, and the lung are all delineated by supraclavicular and subclavicular scanning, and the needle and catheter can also be visualized. Ultrasonographically-assisted jugular and subclavian venipuncture is a simple and helpful procedure to carry out safe venipuncture. This method is particularly recommended for less experienced physicians and for more accurate puncture in patients with distorted cervical or subclavicular anatomic characteristics.

Humans↗

Traumatic giant aneurysm of the external carotid artery.

Because the main trunks of the external carotid artery and maxillary artery are well protected from blunt trauma and superficial penetrating wounds through their course, traumatic aneurysms on these arteries are extremely rare. A 75-year-old woman had struck her occipital region against a door but there was no trauma to the mandibuloauricular region. After 1 month, she noticed a pulsatile mass below her right auricle. At operation an aneurysm was found to be located just distal to the origin of the maxillary artery.

Aged↗