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Biomedical subjects

T J Muckle

Publications and source records attributed to T J Muckle.

44 records · Page 3Linked to original sources

The investigation of myelomatosis by gel isoelectric focusing followed by electrophoresis.

The relatively simple technique of isoelectric focusing in polyacrylamide gel followed by electrophoresis has been applied to the examination of sera and urines from patients both proved and thought to be suffering from myelomatosis. The results obtained from this method correlate well with those obtained by immunoelectrophoresis. Polyclonal gammopathies can be distinguished from the monoclonal variety and gammaG and gammaA myeloma proteins may be readily differentiated from each other. Ig light chain proteins can be demonstrated in both serum and urine.

Agammaglobulinemia↗

The eosinophilic fasciitis syndrome after phenytoin (dilantin) therapy.

A young woman with idiopathic temporal lobe epilepsy developed biopsy-proven oesinophilic fasciitis 16 months after the initiation of phenytoin therapy. Six months after withdrawal of this medication the fasciitis disappeared, and after 5 yr it has not recurred. This case highlights a possible association between the development of oesinophilic fasciitis and the use of medications such as phenytoin.

Adult↗