Search PubMed⌕ Search

Biomedical subjects

T Iwai

Publications and source records attributed to T Iwai.

At least 235 records · Page 13Linked to original sources
PubMed1985

[Familial occurrence of intracranial arteriovenous malformation].

It is beyond that cerebral arteriovenous malformation (AVM) is a congenital disease based on abnormal vascular formation in the embryonic stage. Nevertheless, familial occurrence of cerebral AVMs has been previously reported only in five families throughout the world, when complications of specific diseases such as Sturge-Weber-Dimitri disease, von Hippel-Lindaeu disease, and Osler-Rendu-Weber disease were ruled out. We have recently encountered four cases of two familial AVMs. In this paper, we review nineteen cases of nine familial AVMs from literature including our four cases from two families. Case 1: A 50-year-old male was admitted in June, 1975, for clonic convulsion. Cerebral angiography showed an AVM situated in the left parietal region, which was supplied from callosomarginal and central arteries. Total excision of the AVM was performed. The patient was completely cured and discharged without abnormal neurological deficits. Case 2: A 16-year-old male was admitted in May, 1978, with about ten years history of general convulsions. This patient was the third child of Case 1. Cerebral angiography revealed an AVM situated in the right parietal region, which was supplied from callosomarginal and precentral arteries. Total resection of the AVM was performed. The patient was completely cured. Case 3: An 11-year-old boy was admitted to our hospital in a comatose state in January, 1978, and soon died. Cerebral angiography showed only presence of internal hydrocephalus. The autopsy revealed a hematoma in the right cerebellar hemisphere with bilateral intraventricular hematomas, and AVM was histologically found in the cerebellum.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1984

[Experimental studies on the effect of perfluorochemicals in tumor irradiation].

The effects of radiation therapy with Fluosol-DA on rat mammary tumors were studied. The tissue oxygen tension values of tumors in breathing mixed gas (5% carbon dioxide and 95% oxygen) with Fluosol-DA (25 ml/kg, i.v.) were significantly higher than those in room air without Fluosol-DA. The rats were divided into three groups: Group I received Fluosol-DA but no irradiation, Group II was treated with 1000 rads of irradiation using 60Co without Fluosol-DA in room air and Group III received the same irradiation and Fluosol-DA in breathing mixed gas. In the latter group we observed a prolongation of the survival time and suppression of the tumor growth.

Animals↗
PubMed1984

[Meningioma following irradiation for vascular nevus. A case report].

A case of meningioma that developed 37 years after irradiation therapy for vascular nevus of the scalp over the right frontoparietal region was reported. A 49-year-old male was admitted to the hospital of Gifu University on October 26, 1979, because of a generalized seizure. He had been born with a vascular nevus affecting the right frontoparietal scalp, for which he began receiving local irradiation at the age of 12. The total dose was not known because the only source of information regarding this treatment was the patient's memory. From the age of 17, the suffered from occasional attacks of dysesthesia in the left side of his body without consciousness disorder. He otherwise remained well for the intervening 37 years. Upon admission, he had a vascular nevus remaining with post irradiation skin changes over the right frontoparietal region. General and neurological examination were not remarkable. Right carotid angiogram and CT scan disclosed the presence of a right frontal tumor. A right frontotemporal craniotomy was performed on December 4, 1979 and a hard tumor was found firmly attached to the dura and bone at the right site. All visible tumor and involved bone were completely removed without difficulty. Histological examination of the surgical specimen showed the characteristic features of a transitional meningioma. There was no evidence of malignancy in the sections examined. Since Mann et al reported a malignant meningioma following irradiation therapy for optic nerve glioma, there have been many reports, over seventy cases of so-called radiation-induced meningioma. However, a meningioma following irradiation therapy for vascular nevus of scalp or face is exceedingly rare.(ABSTRACT TRUNCATED AT 250 WORDS)

Carotid Arteries↗
PubMed1981

Successful resection of an aortic arch aneurysm using a temporary trifurcation bypass graft.

Resection of a syphilitic aortic arch aneurysm in a 62-year-old woman was accomplished using a trifurcation temporary bypass system. The bifurcation graft was sutured end-to-side to the ascending thoracic aorta, to the brachiocephalic trunk and to the left common carotid artery, respectively. The attached third limb end was anastomosed end-to-side to the infrarenal abdominal aorta. This technique enabled a large shunt into the abdominal aorta. Occlusion of the iliac arteries proved to be effective in coping with hypotension while attending to the bypass and the volume replacement. The post-operative recovery was uneventful and the patient has remained well after 43 months.

Aorta, Thoracic↗
PubMed1980

Multiple aneurysms of the visceral arteries with migrating vascular bruit on postural change: a case report.

Multiple aneurysms of the gastroepiploic artery and the ileocecal branch of the superior mesenteric artery were found in a 68-year-old male patient by angiography. The patient presented with one-hour postprandial epigastric pain of 10 years duration. Abdominal bruit was auscultated at the two different sites, one of which shifted downwards upon upright position. From the freely movable nature of the great omentum, this bruit, migrating upon postural change, was most likely from the gastroepiploic artery aneurysms. The aneurysms were excised and the abdominal bruit disappeared. The etiology of the aneurysms was suggested to be arterial fibrodysplasia histologically. From this experience, it was stressed that postural change should be added to a routine physical examination to rule out an aneurysm from the freely movable great omentum.

Aged↗
PubMed1980

Elastogenesis in inverted vein graft. An electron microscopic study.

The process of elastogenesis was followed by electron microscopy, from 6 hours to 360 days, in autogenous inverted vein grafts of dogs. The initial processes of the new wall formation over the grafts were similar to those observed in the organization of thrombis. At 40 days, the new wall consisted of three layers comparable to the intima, media and adventitia. New elastic fibers, as demonstrated by orcein stain, were formed around fibroblasts in teh granulation tissue after 20 days and in the adventitia after 40 days. In the media, elastogenesis was associated with smooth muscle cells and began after 40 days. A basement membrane-like material accumulated around smooth muscle cells and, to a much smaller degree, fibroblasts. Elastin aggregates appeared within the basement membrane-like material. These aggregates were stainable with orcein and selectivity digestable with elastase at pH 8.8. The earliest recognizable forms of elastic fibers were the small, spherical to elongated bodies not surrounded by microfibrils. Fused and enlarging elastin aggregates were surrounded by microfibrils.

Animals↗