Biomedical subjects

T Deitmer

Publications and source records attributed to T Deitmer.

65 records · Page 4Linked to original sources

PubMed1986

The influence of nasal obstruction on mucociliary transport.

The influence of nasal obstruction on mucociliary transport is tested by the saccharin test (Andersen). Twenty normal subjects were tested with open nose and subsequently with the nose closed by a clamp. The transport times were significantly longer, when the nose was clamped. It is diScussed that nasal obstruction and missing ventilation leads to changes in the mucus layers by superfluent humidity. This causes a decoupling of the mucociliary transport. Thus a new aspect in pathogenesis of nasal and sinus disease is given.

Biological Transport↗

PubMed1986

[Effect of radiotherapy on the function of the ciliated epithelium in the larynx].

Five human larynges, obtained by surgery, were examined by light and electron microscopy and with an operating microscope, searching for signs of ciliary activity. In two larynges the mucociliary waves could be seen in the subglottic space, whereas a mucociliary transport could not be proved. Via light microscopy, fully ciliated epithelium was found in some cases, in other cases ciliated epithelium was seen only occasionally, whereas in some cases it was absent, substituted by squamous epithelium. The ciliary ultrastructure was normal. The author discusses whether the ciliated structure survives radiotherapy, or whether a regeneration occurs from untreated areas.

Cilia↗

PubMed1986

A modification of the saccharine test for nasal mucociliary clearance.

The saccharine test for assessing mucociliary clearance in the nose is the most practicable method. As the used sodium salt of saccharine is well water soluble, there is suspicion of interference with the very delicate two-layer-system of mucus or transport merely in the periciliary fluid, thus bringing about methodical errors. This is avoided by using inert tracers such as radioactively tagged ion exchange resin particles, which on the other hand must be observed with expensive equipment. A synthesis of both methods is demonstrated by using saccharine loaden ion exchange resin particles. The validity of the test is proven in vitro and in vivo.

Animals↗

PubMed1985

[Rare tumors of the base of the tongue and their therapy].

Five rare tumours of the base of the tongue are reported. Diagnosis and therapy of a tuberculoma, an amyloid tumour, a mucoepidermoid carcinoma, a pleomorphic adenoma, and an angioleiomyoma are illustrated. The frequency and other possible sites of these tumours are discussed based on a review of the literature. The standard surgical approaches to the base of the tongue are described, favouring lateral pharyngotomy. The need for careful planning of the operation is stressed including difficulty in intubation and control of bleeding after operation.

Adolescent↗

PubMed1984

[Histiocytosis X in the field of otorhinolaryngology].

This is a report on five cases of histiocytosis x with manifestations in ENT. Based on our own experience and reports in the literature the recommendation is given to search for further foci of the disease even in the case of an eosinophilic granuloma, which is generally presumed to be unilocular. Therapeutic steps should be taken only after having established thorough staging.

Adolescent↗

PubMed1984

[Aerodynamic effect of tracheal voice tubes].

A usual rhinomanometer was used to construct an apparatus to measure the aerodynamic resistance of a tracheostomy speaking tube lying in the trachea. This resistance, evoked by the sieve or the hole in the tube, is considerable. A model of a trachea was made from a silicone tube to assess the resistance of several types of tracheostomy speaking tubes.

Airway Resistance↗

PubMed1984

[Prevention of complications of the transnasal placement of artificial respiration tubes and catheters].

The anatomical variations of the nose and the nasopharynx concerning the possible complications in placement of transnasal tubes are discussed, such as problems with septal deviations, retropharyngeal or even intracranial aberration. In order to avoid complications attributable to these techniques the use of instruments designed for anterior rhinoscopy is recommended. No convenient and practicable instrument for routine use by an anaesthesiologist has been developed to date.

Humans↗

PubMed1984

[Diagnostic value of bone scintigraphy in otorhinolaryngology].

18 patients with inflammatory or neoplastic diseases of the skull underwent bone scintigraphy; the scintigraphic and radiologic findings were compared with the extent of the lesion found at surgery. Possible errors and the diagnostic value of this method are discussed.

Facial Bones↗

PubMed1983

[Pathogenesis of laryngeal cancer in women. A clinical and follow-up study].

Clinical findings and age distribution of 71 female patients with laryngeal cancer seen in the ENT department of the University of Münster between 1961 and 1981 are reported. Of these patients, 26 could be questioned with regard to their habit of smoking and relevant gynaecological biographical data. They were compared with an equal number of patients of the same age not suffering from hormone-dependent diseases. With regard to histology, localisation or TNM staging, no signs of laryngeal cancer in women could be found compared to male patients reported in the literature. From the data gathered by questioning, it is possible to conclude that certain trends are represented, suggesting two pathogenetic types of laryngeal cancer in women: 1. Cancer of a young, non-smoking woman, showing signs of virilism. 2. Cancer of an older, smoking woman without signs of virilism.

Adult↗

PubMed1981

[The role of zoster oticus as a paraneoplastic syndrome (author's transl)].

The relation between malignant neoplasms and zoster oticus as a paraneoplastic syndrome is discussed based on a bibliographic review and catamnestic evaluations of own patients. 19 patients who had suffered from zoster oticus were included in a follow-up study covering a period up to 13 years after the affection. The symptoms of zoster oticus as described in the literature are reviewed and compared with the findings in our patients. Although there were no indications of neoplasms in our patients a general check-up is recommended in all cases of zoster oticus in accordance with the rules established in internal medicine and dermatology.

Adult↗

PubMedDate not supplied

Nasal physiology in swimmers and swimmers' sinusitis.

To investigate the pathogenesis of swimmers' sinusitis we questioned and examined a group of 20 swimmers and 20 controls. Clinical examination was followed by rhinomanometry, sonography of the maxillary sinuses, a saccharine test to assess mucociliary transport in the nose, and a viable cytological sampling of the nasal mucosa. The history showed a preponderance of symptoms of sinusitis and chronic rhinitis in the swimmers' group, as well as a reddening of the nasal mucosa and a swelling of the adenoids. Sonography showed mucosal thickening in the antrum in more cases among the swimmers. Rhinomanometry, saccharine test, and viable cytological sampling revealed no differences of significance between the groups. It is discussed that pathogenesis is more probable through cooling of the skin of the face and the whole body than by entrance of water into the upper respiratory tract.

Adolescent↗