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Biomedical subjects

T D Taylor

Publications and source records attributed to T D Taylor.

At least 37 records · Page 2Linked to original sources
PubMed1998

Problems associated with implant rehabilitation of the edentulous maxilla.

Implant rehabilitation of the edentulous maxilla is one of the most challenging endeavors that faces the restorative dentist. Comprehensive diagnosis and precise evaluation of the patient's needs followed by appropriate treatment planning provide the restorative dentist with the necessary tools to satisfy patient expectations and the realization that this patient would greatly benefit from this treatment or that the patient should be referred to a prosthodontist for further evaluation. Not enough emphasis can be placed on adequate placement of the implants by the surgeon. As with any rehabilitation, aesthetics are of prime importance to the patient, and proper occlusion confers longevity to the prosthesis. Whether a removable or fixed implant-supported prosthesis is fabricated, every step is crucial and is reflected in the final product. When all sequences of treatment are properly executed, the successful implant rehabilitation of the maxilla is one of the most gratifying procedures for both the restorative dentist and the patient.

Dental Implantation, Endosseous↗
PubMed1998

Algorithms for the treatment of cleft lip and palate.

Developing standardized outcomes and algorithms of treatment is a constantly evolving task. This article examines four variables in this process: cleft type, operative technique, surgical experience, and timing. Input from international cleft lip and palate programs regarding techniques and treatment modalities provide a dynamic tool for assessment and the development of guidelines in the treatment of the cleft lip and palate patient.

Adolescent↗
PubMed1998

Applications of distraction osteogenesis. Part I.

Distraction osteogenesis (DO) of facial bones is a recent development in the treatment of pediatric patients. The use of DO in current clinical practice of pediatric reconstructive surgery is primarily limited to severe deformities of the lower jaw, most of which are congenital in nature. Clinical experience with DO for early facial deformities remains limited, and no authoritative works are currently available to guide clinicians in the techniques or indications for DO of the facial skeleton.

Child↗
PubMed1996

Homozygosity mapping of Hallervorden-Spatz syndrome to chromosome 20p12.3-p13.

Hallervorden-Spatz syndrome (HSS) (OMIM #234200) is a rare, autosomal recessive neurode-generative disorder with brain iron accumulation as a prominent finding. Clinical features include extrapyramidal dysfunction, onset in childhood, and a relentlessly progressive course. Histologic study reveals massive iron deposits in the basal ganglia. Systemic and cerebrospinal fluid iron levels are normal, as are plasma levels of ferritin, transferrin and ceruloplasmin. Conversely, in disorders of systemic iron overload, such as haemochromatosis, brain iron is not increased, which suggests that fundamental differences exist between brain and systemic iron metabolism and transport. In normal brain, non-haem iron accumulates regionally and is highest in basal ganglia. Pathologic brain iron accumulation is seen in common disorders, including Parkinson's disease, Alzheimer's disease and Huntington disease. In order to gain insight into normal and abnormal brain iron transport, metabolism and function, our approach was to map the gene for HSS. A primary genome scan was performed using samples from a large, consanguineous family (HS1) (see Fig. 1). While this family was immensely powerful for mapping, the region demonstrating homozygosity in all affected members spans only 4 cM, requiring very close markers in order to detect linkage. The HSS gene maps to an interval flanked by D20S906 and D20S116 on chromosome 20p12.3-p13. Linkage was confirmed in nine additional families of diverse ethnic backgrounds.

Chromosome Mapping↗
PubMed1996

Total midface reconstruction after radical tumor resection: a case report and overview of the problem.

We report an unusual repair of a massive midface defect resulting from resection of a recurrent squamous cell carcinoma of the nasal vestibule. The defect included both maxillas, the hard palate, the upper lip, and all nasal and perinasal tissues. After treatment, reconstruction was accomplished using prostheses and autologous tissue transferred from local and distant sites. The osseous component of the transferred tissue permitted placement of osseointegrated implants for fixation of maxillary and nasal prostheses. The rationale for this reconstruction and the problems associated with midface reconstruction after radical tumor resection are discussed.

Carcinoma, Squamous Cell↗
PubMed1994

Alloplastic implants. Their role in reconstruction of the mandible.

This article discusses the use of osseointegrated implants in mandibular reconstruction. Although the article presents the history, indications, and complications of this technique, the primary focus of the article is the technique itself, especially how the technique varies from patients not undergoing reconstruction to those who are. The effect of radiation therapy on the treatment planning of patients undergoing reconstruction also is discussed. Intraoral soft-tissue management also is addressed, as this area often differs significantly in patients undergoing radiation therapy from that in patients not undergoing radiation therapy and reconstruction.

Adult↗
PubMed1993

Osseointegrated implant rehabilitation of the previously irradiated mandible: results of a limited trial at 3 to 7 years.

The use of osseointegrated dental implants in patients with defects of the head and neck acquired as a result of ablative surgery for malignancy is an accepted and valuable extension of the well-documented use of these implants for the treatment of edentulism. In patients who have received ionizing radiation as part of tumor therapy, the use of dental implants is poorly documented. A limited trial of 21 Brånemark implants placed in the previously irradiated mandibles of four patients is reported here. The implants have been in place and functioning for periods of 3 to 7 years. No implants have been lost. Patient selection, treatment, and complications encountered are discussed. Guidelines for further use of osseointegrated implants in patients with previously irradiated mandibles are suggested.

Carcinoma↗
PubMed1992

Use of bovine osteogenic protein to promote rapid osseointegration of endosseous dental implants.

An enriched bovine osteogenic protein preparation in combination with bone collagen matrix (osteogenic protein device) was used to effect new bone growth in extraction sites in the presence or absence of titanium dental implants. Incisor and canine teeth were extracted from each of three cynomolgus monkeys, and implants were inserted directly into the sockets without surgical site preparation. The osteogenic protein device induced new bone formation in close apposition to the titanium implants in all trials within 3 weeks. A lesser amount of new bone formation in both sets of control sites was limited to the bony socket walls and not closely apposed to the implant. These data show that the osteogenic protein device is capable of inducing new bone formation in tooth sockets within 3 weeks in the presence or absence of titanium implants. This is the first known demonstration of the therapeutic induction of bone formation in close apposition to metallic implants.

Animals↗
PubMed1992

Mandibular restoration in the cancer patient: microvascular surgery and implant prostheses.

This article deals with state of the art reconstruction and rehabilitation of the head and neck cancer patient who requires mandibular resection. The mandible can be reconstructed by microvascular free tissue transfer of bone and soft tissue from distant body sites. The dental units and missing soft tissue contours can be supported by osseointegrated implants placed in the grafted bone. This article discusses the rationale for patient selection and sequencing of this complex and rewarding rehabilitation.

Dental Implants↗
PubMed1991

Ulcerative lesions of the palate associated with removable partial denture castings.

Regions of inflammation with or without ulceration beneath removable partial dentures have been of concern to prosthodontists for many years. The etiology of these lesions has not been established, but potential factors are microbial infection, obstructive sialadenitis, and allergic-type reactions to the metal framework. A new etiological factor that may be involved is described. Focal pitting corrosion and by-products of corrosion in nickel-chromium alloys are discussed as toxic agents responsible for palatal lesions. Six patient reports that include results of tissue biopsy and EDAX analysis of casting are presented.

Adult↗
PubMed1991

Fixed implant rehabilitation for the edentulous maxilla.

The edentulous maxilla presents, perhaps, the greatest challenge to implant therapy. The anatomic, esthetic, and functional demands for fixed reconstruction of the maxillary arch are affected by many variables, some of which are controllable by the surgeon and dentist. This paper describes those variables and offers suggestions for managing the controllable aspects of treatment while avoiding the uncontrollable ones. Suggestions for planning the surgical and prosthodontic phases of treatment are described.

Dental Implants↗
PubMed1990

A boxing technique for making moulages of facial defects.

A technique using irreversible hydrocolloid in conjunction with conventional boxing method is described for making impressions of facial defects. The technique improves control of impression material without causing distortion of soft tissue adjacent to facial defects.

Colloids↗
PubMed1989

A 10-year report of a longitudinal recall of overdenture patients.

Eighty-nine patients were evaluated longitudinally for a 10-year period to assess the periodontal health of overdenture abutments and the effectiveness of the overdenture treatment. Of the original group, 28 patients returned for the 10-year recall. Sixty-six of the 77 overdenture abutments were present. Seven of the 11 abutment teeth extractions were because of caries and four were the result of periodontal disease. Most of the abutments have progressively lost attached tissue. Other periodontal indices remained fairly constant. Most of the patients were satisfied with the treatment even though the periodontal assessment was less than ideal.

Aged↗