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Biomedical subjects

T D Taylor

Publications and source records attributed to T D Taylor.

At least 19 recordsLinked to original sources
PubMed1992

Use of bovine osteogenic protein to promote rapid osseointegration of endosseous dental implants.

An enriched bovine osteogenic protein preparation in combination with bone collagen matrix (osteogenic protein device) was used to effect new bone growth in extraction sites in the presence or absence of titanium dental implants. Incisor and canine teeth were extracted from each of three cynomolgus monkeys, and implants were inserted directly into the sockets without surgical site preparation. The osteogenic protein device induced new bone formation in close apposition to the titanium implants in all trials within 3 weeks. A lesser amount of new bone formation in both sets of control sites was limited to the bony socket walls and not closely apposed to the implant. These data show that the osteogenic protein device is capable of inducing new bone formation in tooth sockets within 3 weeks in the presence or absence of titanium implants. This is the first known demonstration of the therapeutic induction of bone formation in close apposition to metallic implants.

Animals↗
PubMed1992

Mandibular restoration in the cancer patient: microvascular surgery and implant prostheses.

This article deals with state of the art reconstruction and rehabilitation of the head and neck cancer patient who requires mandibular resection. The mandible can be reconstructed by microvascular free tissue transfer of bone and soft tissue from distant body sites. The dental units and missing soft tissue contours can be supported by osseointegrated implants placed in the grafted bone. This article discusses the rationale for patient selection and sequencing of this complex and rewarding rehabilitation.

Dental Implants↗
PubMed1991

Ulcerative lesions of the palate associated with removable partial denture castings.

Regions of inflammation with or without ulceration beneath removable partial dentures have been of concern to prosthodontists for many years. The etiology of these lesions has not been established, but potential factors are microbial infection, obstructive sialadenitis, and allergic-type reactions to the metal framework. A new etiological factor that may be involved is described. Focal pitting corrosion and by-products of corrosion in nickel-chromium alloys are discussed as toxic agents responsible for palatal lesions. Six patient reports that include results of tissue biopsy and EDAX analysis of casting are presented.

Adult↗
PubMed1991

Fixed implant rehabilitation for the edentulous maxilla.

The edentulous maxilla presents, perhaps, the greatest challenge to implant therapy. The anatomic, esthetic, and functional demands for fixed reconstruction of the maxillary arch are affected by many variables, some of which are controllable by the surgeon and dentist. This paper describes those variables and offers suggestions for managing the controllable aspects of treatment while avoiding the uncontrollable ones. Suggestions for planning the surgical and prosthodontic phases of treatment are described.

Dental Implants↗
PubMed1990

A boxing technique for making moulages of facial defects.

A technique using irreversible hydrocolloid in conjunction with conventional boxing method is described for making impressions of facial defects. The technique improves control of impression material without causing distortion of soft tissue adjacent to facial defects.

Colloids↗
PubMed1989

A 10-year report of a longitudinal recall of overdenture patients.

Eighty-nine patients were evaluated longitudinally for a 10-year period to assess the periodontal health of overdenture abutments and the effectiveness of the overdenture treatment. Of the original group, 28 patients returned for the 10-year recall. Sixty-six of the 77 overdenture abutments were present. Seven of the 11 abutment teeth extractions were because of caries and four were the result of periodontal disease. Most of the abutments have progressively lost attached tissue. Other periodontal indices remained fairly constant. Most of the patients were satisfied with the treatment even though the periodontal assessment was less than ideal.

Aged↗
PubMed1989

Clinical evaluation of a nystatin pastille for treatment of denture-related oral candidiasis.

Nystatin has been formulated in the form of a flavored pastille (troche) as an alternative to the oral suspension. This parallel, double-blind, randomized, placebo-controlled study evaluated the acceptance and effectiveness of the nystatin pastille at two different dosages. Twenty-four subjects were selected on the basis of clinical signs of denture stomatitis and culture isolation of Candida spp. Each subject was randomly assigned to one of three treatment groups (A, 200,000 units; B, 400,000 units; and C, placebo). At entry, 7 days, 14 days, and at 10 days after cessation of treatment, the clinical condition was evaluated and Gram stain smears and imprint cultures were made and analyzed. The flavored pastille was well accepted by the subjects and both dosages were shown to be effective in significantly reducing or eliminating the Candida organism during active therapy. Data from the 10-day follow-up, however, demonstrated reinfection with the organism. Thus to resolve the condition, effective therapy must include treatment of the etiologic factors of denture stomatitis along with antimicrobial therapy.

Candidiasis, Oral↗
PubMed1989

Osteogenesis of the mandible associated with implant reconstruction: a patient report.

A patient report is presented illustrating bone growth of the posterior mandible associated with a fixed implant reconstruction of the Brånemark type. In this instance, the mandible had grown vertically approximately 3 mm and was causing discomfort beneath the cantilever sections of the prosthesis because of gingival impingement between the restoration and the bony mandible. The literature relative to osteogenesis associated with osseointegrated implants is reviewed.

Dental Implantation, Endosseous↗
PubMed1988

Collagen/hydroxylapatite implant for augmenting deficient alveolar ridges: twelve-month clinical data.

In a multicenter study, 77 edentulous patients had mandibular augmentation with implants of purified fibrillar collagen combined with dense hydroxylapatite (Alveoform Biograft); 22 of these patients also had maxillary augmentation. Most patients had Class III or IV mandibular atrophy, and had outpatient surgery with the subperiosteal tunneling technique. Temporary splints were worn for 24 hours post-surgery. Mean ridge height was 15.3 mm before surgery and 19.5 mm after 12 months, an augmentation of 4.2 mm. Predictable compaction occurred largely in the first few months after denture loading. Most patients, surgeons, and prosthodontists assessed the results of the procedure as good to excellent at 1 year following implantation. Adverse experiences, largely dehiscence and paresthesia, tended to resolve over time. Sera from ten patients demonstrated antibodies to bovine collagen that were not clinically significant. Alveolar augmentation with collagen/hydroxylapatite achieved clinically significant results that compared favorably with those achieved with other types of ceramic implants.

Adult↗
PubMed1987

Evaluation of collagen/hydroxylapatite for augmenting deficient alveolar ridges: a preliminary report.

A multicenter study was undertaken to evaluate a new alveolar ridge augmentation material composed of purified fibrillar collagen and particulate hydroxylapatite (PFC/HA). In a study of 77 patients and 99 reconstructed ridges, this material provided superior handling properties over HA alone as evidenced by its ease of surgical placement and manipulation, and the rarity of particle migration or displacement. Moreover, the rapid development of ridge firmness and stability allowed for the loading of dentures within three to six weeks. Prosthodontist evaluations and surveys of patient satisfaction showed great satisfaction with denture fit, comfort, esthetics, speech, and ability to masticate.

Adult↗