Biomedical subjects
Publications and source records attributed to T Ando.
A simple and effective method to diminish the amount of blood loss during the Bentall operation is described. This method is to connect the perigraft space between the aneurysmal wall and the aortic graft with the right atrium using a small plastic tube.
Over the past eight years at the OMCH Fogarty balloon catheter have been used for one hundred instances of acute arterial occlusion and for twenty instances of venous thrombosis. Compication developed on seven occasions, three in the operation for arterial thrombosis and four during venous thrombectomy. Three types of complications in the arterial system were encountered: removal of intima with thrombi, arterial rupture and thrombotic occlusion due to dissection of intima. All of these complications were successfully treated with appropriate procedures. Two types of complications in the venous system were encountered: perforation of iliac vein by the tip of the catheter (3 cases) and loss of the balloon intravenously (1 case). In the former complicated group, the first case died of hemorrhagic shock, the second case recovered uneventfully without any procedures and the last case was successfully trated by operative hemostatic procedure. In the case of latter complication, it was not possible to remove the lost balloon in the left posterior tibial vein in spite of strenuous efforts to retrieve it. Detailed discussion for prevention or treatment of these complications was done chiefly based on our experience.
Oral high-dose medroxyprogesterone acetate (MPA) treatment (600, 800, 1200 mg/day or changed dosage) was given to 49 patients with recurrent breast cancer from January 1979 to December 1992. The overall response rate to MPA was 38.8% (19/49). The response rate in the soft tissue was significantly higher compared with that in bone metastases or in visceral metastases. MPA was effective on patients both with or without previous treatment. Several side effects were recognized, but they were mild and tolerable. These results demonstrate that MPA is effective when used as first line or second line treatment.
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PSK, a protein-bound polysaccharide derived from basidiomycetes, is a biological response modifier that exhibits a variety of activities following oral administration, including prevention of infection. In this study, the effects of oral administration of this drug on microbial flora of tumor-bearing mice were examined. Numbers of Staphylococcus, Streptococcus and Pseudomonas were increased, and those of Bifidobacterium and Lactobacillus were reduced in fresh feces of mice from later than 9 weeks after inoculation of sarcoma 180. However, these changes were prevented by oral administration of PSK. In mice bearing sarcoma 180, the increases in numbers of Staphylococcus and Pseudomonas and the decrease in those of Bifidobacterium were further enhanced by intraperitoneal administration of anticancer agent mitomycin C, but such changes were suppressed by oral administration of PSK. These results suggest that PSK has a preventive effect against abnormal conditions of the intestinal flora induced by tumor inoculation or the administration of anticancer agents.
The effect of training on the ability to use dental floss was evaluated in a study involving forty-eight children in the 6.5 to 7.5 age-group. Using a dental plaque index for the proximal surfaces, we observed significantly superior average results for the trained group (five weekly sessions) relative to the group with no training. We also observed a significant average difference favoring the male trained group relative to the female trained group.
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This article describes the surgical techniques and indications of laparoscopic partial hepatectomy, which is not as widely available as laparoscopic cholecystectomy. Three patients with hepatocellular carcinoma and associated severe liver cirrhosis were candidates for this technique from July 1993 to August 1994. The tumor size was 4 cm or less and all the tumors were located in segment 5 or 8 which had grown nodularly and protruded from the liver surface. A microwave tissue coagulator was used for parenchymal dissection under ultrasonographic guidance in a gas-less method with or without low-pressure pneumoperitoteum of 4 mmHg. The principle of dissection consists of tissue coagulation and fragmentation with dissecting forceps. Three hepatectomies were performed uneventfully without blood transfusion and the patients rapidly returned to their preoperative conditions. The laparoscopic partial hepatectomy can be an option of treatment in selected cases where the tumor can be removed by minor, superficial resection.
Only very rarely do multiple parapapillary choledochoduodenal fistulas occur concurrently with ampullary carcinoma. The following presents just such a case, which occurred in a 51 year-old Japanese female hospitalized for epigastralgia. Gastrointestinal fiberscopy (GIF) showed abnormal swelling of Vater's papilla. She was diagnosed as having ampullary carcinoma and choledochoduodenal fistulas, as determined by hypotonic duodenography (HDG), endoscopic retrograde cholangiopancreatography (ERCP) and from the histopathology of the ampullary mucosal biopsy. Pancreatoduodenectomy was performed. We postulated that the multiple fistulas were formed on the longitudinal fold of Vater's papilla by an ampullary carcinoma, and that the fistulas played a major role in bile drainage. As a result, jaundice was not seen throughout the entire clinical course. We report on the mechanism of fistula formation, with a review of the recent literature.