[Spinal deformity and disturbance of activity of daily life].
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Activities of Daily Living↗
Biomedical subjects
Satoshi Mori
Publications and source records attributed to Satoshi Mori.
[Effects and safety of SERM in animal study].
SERM (estrogen receptor modulator) has the different effects of both estrogen agonist and antagonist depending on the organs. Raloxifene has been developed as a medicine for the treatment of postmenopausal osteoporosis, which reduces bone loss by suppressing bone resorption after ovariectomy (estrogen agonist for bone), while not increasing the proliferation of uterine endometrium or estrogen sensitive mammary cancer (estrogen antagonist for uterus or mamma).
English Abstract↗
[Evaluation of the material property of the bone].
Strength of bone is determined by the volume, the structure and the quality of the bone. Microdamage can be detected in bone by bulk stain method, which is one of the major determinant of the bone fatigue. Microdamages are accumulated in the femoral head trabecular bone of aged subjects and femoral neck fracture patients. Microdamage is repaired in vivo by bone remodeling.
English Abstract↗