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Biomedical subjects

S Young

Publications and source records attributed to S Young.

At least 289 records · Page 16Linked to original sources
PubMed1982

Spongiform encephalopathy of Rocky Mountain elk.

A disease with striking clinical and pathologic similarities to the spongiform encephalopathies is described in six Rocky Mountain elk (Cervus elaphus nelsoni) maintained in wildlife facilities in Colorado and Wyoming. Clinical signs included behavioral alterations and progressive weight loss over a period of weeks or months. Consistent microscopic lesions were limited to the central nervous system and characterized by widespread spongiform transformation of the neuropil, intracytoplasmic vacuoles in neuronal perikaryons, and astrocytic hypertrophy and hyperplasia.

Animals↗
PubMed1982

Sheep pulmonary adenomatosis (jaagsiekte) in the United States.

Morphologic features of 8 cases of sheep pulmonary adenomatosis in the United States are described. All cases were studied by light microscopy and 1 case, by electron microscopy. The common finding in all sheep was an adenoma composed of fetal type II alveolar epithelial cells. The stroma closely resembled interalveolar septa in most areas. In other areas, there was excessive collagenous or myxomatous tissue. Metastatic tumor in mediastinal lymph nodes of 2 sheep closely resembled tumor in the lung. A virus with cultural and structural characteristics like those of ovine progressive pneumonia virus was isolated from the lungs of 1 sheep, but neither virions nor viral inclusions were seen in the pulmonary parenchyma.

Animals↗
PubMed1981

Aspects of social support networks among institutionalized adolescents.

This study describes the social support networks on two adolescent units in two mental health centers. The purpose is to explore the possible existence and functions of informal peer support groups. A semi-structured interview schedule consisting of six questions was used. Participant observation was also used as a secondary method to substantiate the interview responses of 16 patients and 4 staff members (10 patients and 2 staff members on one ward and the remainder on the other ward). The results indicate that some form of peer support network exists on the wards as well as outside the institutions. Two emergent types of network, with some overlapping, are the action-oriented and the dialogue-oriented, with age and gender as the factors discriminating between them. Conclusions from the results are suggestive rather than conclusive. A much more extensive study would need to be undertaken to decisively refute or support the significance of peer groups among instiutionalized adolescents.

Adolescent↗
PubMed1980

Health centre's success story.

The success of Selly Oak's new health centre is apparent from many points of view. Jane Dicks, Richard Miles and Stan Young, all of South Birmingham Health District describe the problems faced and how they were solved to maintain a prodigious building schedule.

Community Health Centers↗
PubMed1980

The effect of acute hyperglycaemia on the retinal circulation of the normal cat.

The retinal microcirculation of anaesthetised normal cats was studied during hyperglycaemia (15 to 55 mmol/l) induced by intravenous infusion of glucose, using high speed cine fluorescence angiography. Saline (0.150 mmol/l) was infused as a control for the volume effect of glucose solution and equiosmolar mannitol was infused as a control for the osmotic effect. The mean retinal arteriolar inflow rate increased from 34 +/- 1 mm/sec to 41 +/- 4 mm/sec during glucose infusion, and from 46 +/- 1 mm/sec to 56 +/- 3 mm/sec during mannitol infusion. The blood pressure similarly increased from 105 +/- 5 mmHg to 125 +/- 2 mmHg during glucose infusion and from 110 +/- 7 mmHg to 129 +/- 1 mmHg during mannitol infusion. During mannitol infusion the increased inflow was accompanied by a reduction in the arteriolar width so that the volume flow remained unchanged. During glucose infusion this constriction did not occur, resulting in a significantly increased volume of retinal blood flow (9 +/- 1 microliter/min to 12 +/- 1 microliter/min).

Animals↗
PubMed1980

Further examples of the Wulfsberg antigen.

4 Wu-positive donors were found in a total of 16,476 South Australians. Family studies showed Wu to be independent of the Lutheran and P blood group systems. Of six examples of anti-Wu detected in 4,200 blood donors by a Technicon AutoAnalyzer, only two were detectable manually.

Australia↗
PubMed1980

Chronic wasting disease of captive mule deer: a spongiform encephalopathy.

In the past 12 years (1967-79) a syndrome we identify as chronic wasting disease has been observed in 53 mule deer (Odocoileus hemionus hemionus) and one black-tailed deer (Odocoileus hemionus columbianus) held in captivity in several wildlife facilities in Colorado and more recently in Wyoming. Clinical signs were seen in adult deer and included behavioral alterations, progressive weight loss and death in 2 weeks to 8 months. Gross necropsy findings included emaciation and excess rumen fluid admixed with sand and gravel. Consistent histopathologic change was limited to the central nervous system and characterized by widespread spongiform transformation of the neuropil, single of multiple intracytoplasmic vacuoles in neuronal perikaryons and intense astrocytic hypertrophy and hyperplasia. Presented is a clinical characterization of chronic wasting disease and pathologic evidence supporting the conclusion that the disease is a specific spontaneously occurring form of spongiform encephalopathy.

Animals↗