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Biomedical subjects

S Wolf

Publications and source records attributed to S Wolf.

At least 343 records · Page 19Linked to original sources

The presence of 2,3-butanediol in the blood of chronic alcoholics admitted to an alcohol treatment center.

Fifty-one of sixty-three unselected alcoholic subjects had 2,3-butanediol in their blood in concentrations ranging from 0.011 to 0.775 mM upon admission to an alcohol detoxification center. The concentration of 2,3-butanediol was below the detection limit of 0.01 mM in twelve non-alcoholic controls. Eighteen hours after admission, second blood samples showed no ethanol in all eleven subjects tested. 2,3-Butanediol levels declined in all of the patients and became undetectable in eight.

Adolescent↗

Spontaneous migration of a central venous catheter and its repositioning: technical note.

A right atrial catheter was inserted the night before operation and its position was verified by an X-ray film. Before the performance of the surgical procedure, the catheter was attached to a strain gauge transducer and a wave form indicated catheter migration into the right ventricle. The catheter was withdrawn until atrial pulse contour developed. Verification of catheter position using this pressure pulse contour technique is simple and accurate and avoids the potential hazards of ventricular placement and the inability to aspirate adequately in the event of venous air embolism.

Adult↗

[Malignant fly-grub infection (myiasis) of the ear (author's transl)].

On the basis of an own observation of a malignant fly-grub infection of the ear and by means of a detailed checking of the literature a benignant and a malignant shape of this disease are distinguished. The peculiarities of the mode of infection in relation to the fly-species are described, some apparent typical characteristics of the Muscidae-Larva infection are put out and directions for treatment are given. The disease nearly wrotten in Europe to-day was not a seldom event especially in the eastern parts of Germany.

Aged↗

QT interval prolongation as predictor of sudden death in patients with myocardial infarction.

Fifty-five patients with recent myocardial infarction and 55 healthy controls, matched for age, sex, race, height, weight, education and job, had an electrocardiogram taken every two months for seven years. Twenty-eight patients and one control had a sudden cardiac death. The QTc (mean of all values recorded) was found prolonged in one control (2%), five of 27 surviving patients (18%) and in 16 of 28 patients who had sudden death (57%). The difference between surviving and sudden death patients is significant (P less than 0.01). It is interesting that the only control with a long QT was the one when died suddenly of myocardial infarction. Among patients with previous myocardial infarction a prolonged QTc constitutes a 2.16 times greater risk for sudden death. We conclude that a constant prolongation of QTc in patients with myocardial infarction may help, with other risk factors, in defining a subgroup at higher risk for sudden death.

Adult↗

A method for selecting criteria to evaluate medical care.

This study tests a questionnaire method for eliciting process criteria for medical care appraisal. The questionnaire was sent to national samples of family physicians, pediatricians, and pediatricians specializing in infectious diseases asking their opinions about various clinical actions in 125 clinical situations concerning respiratory infection in infants. Five hundred twenty-four (54%) physicians returned completed questionnaires. Questionnaire responses favored the performance of a majority of actions and opposed very few. Opinions concerning individual actions, particularly diagnostic tests and treatments, varied widely depending upon the clinical situation presented. A second questionnaire sent one year later indicated that the opinions expressed in the first questionnaire remained stable over time, especially if the initial opinion favored performance of the action. Comparison of the questionnaire responses and medical records of a group of practitioners demonstrated that only 55% of actions favored in a practitioner's questionnaire appeared in his records. Although the questionnaire method appears to be a feasible, specific, and reliable means of identifying clinical opinion, there remains considerable discordance between opinion as expressed in the questionnaire and recorded clinical practice.

Humans↗