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S Westin

Publications and source records attributed to S Westin.

At least 55 records · Page 3Linked to original sources

Methods for quality assessment in general practice.

BACKGROUND AND OBJECTIVES: There is now a wide variety of methods available to general practitioners who want to engage in quality assessment, quality assurance, or quality improvement activities in their practices. These methods require some kind of performance review, or at least the collection of some performance-related data. As in traditional research, the choice of methods depends on what research questions one wants to address. This paper elaborates on some key concepts related to the choice of methods, making a distinction between whether any method actually covers performance (what a doctor does in daily practice) or competence (what a doctor is capable of doing) as well as a distinction between whether a method is direct (patient-doctor contact is observable) or is indirect. METHOD: An overview frame will be presented of the methods most commonly used for data collection within quality assessment. These methods are discussed on their validity, reliability, feasibility and acceptability. Direct methods aimed at recording performance are assumed to hold the highest validity, but practical, economic and logistic factors may favour less ambitious methods for audit or quality improvement activities. CONCLUSIONS: One crucial element in all methods is creating a set of empirical data, as a basis for comparisons, reflection, dialogue and discussions among colleagues.

Data Collection↗

[Standardized patients in general practice--a new method for quality assurance in Noway].

Standardized patients were sent to general practitioners who use the patient list system in Trondheim in order to register daily clinical practice without the patient being unmasked. The authors explain what a standardized patient is, how they are taught to present a disease, and how they report on the consultation in a valid and reliable way. They also describe how the standardized patients were introduced into the doctors' patient list system. The doctors were informed about the project in advance. Twenty-three doctors were visited twice and one doctor was visited once by a standardized patient. At two of the visits the patient was unmasked. The conclusion is that the use of standardized patients is a valid, reliable and practical method for quality assurance in general practice in Norway.

Family Practice↗

[Assessment by consulting physicians and general practitioners about complex disability pension matters].

In the study we wanted to explore physicians' judgement of applicants for disability benefit who have complex medical and psychosocial histories. A postal questionnaire was used, containing six patient management problems focusing on whether the applicant would fill the criteria for obtaining a disability benefit according to Norwegian legislation. The participants were all medical officers hired as consultants by the social security officers in Norway (n = 122, response rate 75%) and a random sample of Norwegian general practitioners (n = 160, response rate 55%). There was a high degree of variation among physicians. The tendency to spread was almost parallel in the two groups of doctors, but the general practitioners tended to be slightly more liberal (in favour of disability benefit) than the social security medical officers. The latter expressed a more optimistic view of the rehabilitation potential of the applicants. Some physicians in each group seemed to be generally restrictive, others were liberal. Younger doctors seemed to be slightly more restrictive than older ones, while the attitudes of the physicians did not seem to be influenced by their sex, the form of payment or the location of the practice. The variation within each group of doctors indicates that both feedback and further discussion are needed to improve quality in this field of social security medicine.

Adult↗

[What happens to patients not granted disability pension?].

Subsequent to a recent (1991) narrowing of the medical legibility criteria for granting disability pensions in Norway, we wanted to follow up rejected applicants with regard to main sources of income. As setting were chosen five mainly rural municipalities on the North-West coast of Norway and the city of Trondheim. The study was carried out as a historic prospective study of a sample of rejected applicants for a disability pension, mainly based on follow-up data from local social security offices. Among a sample of 146 applicants rejected in 1990/91 and 1992, 143 (87 women and 56 men) were available for the analysis in March 1994. A rather stable 20% of the sample were occupationally active throughout three years of follow-up, this percentage being slightly higher among women than among men. In spite of the initial rejection, 25% had been granted a disability pension after two years. The rest received other kinds of public social support, or had left the labour market and had no social security support (mostly women).

Adult↗

Characterization of orphan nuclear receptor binding elements in sex-differentiated members of the CYP2C gene family expressed in rat liver.

The HepG2-specific P450 2C factor motif (HPF1-motif) is conserved in many hepatic cytochrome P450 genes (CYP). Its functional importance for rabbit CYP2C genes has led to the proposal that the HPF1 motif acts as a common regulator for the liver-specific expression of CYP2 genes with hepatic nuclear factor (HNF)-4 being the corresponding trans-activator. The HPF1-like elements in the rat CYP2C genes 2C7, 2C11, 2C12, and 2C13 have been studied with regard to functional importance and binding of the orphan receptors HNF-4, apoAI regulatory protein-1 (ARP-1), and v-erbA-related receptors (EAR) 3 and 2. Binding activity in rat liver nuclear extracts includes these orphan receptors as judged from electromobility supershift experiments and from results obtained with expressed receptors, although the element in CYP2C11 did not bind HNF-4. Mutations of the HPF1-like elements in the CYP2C7, CYP2C11, and CYP2C12 promoters had marginal effects on the expression of luciferase reporter gene constructs transiently transfected into HepG2 cells, whereas for CYP2C13 the activity was reduced to 60% of the wild type construct. Coexpression of HNF-4 in COS-7 cells had limited effect on the luciferase activity generated from the 2C promoters, maximally 3-fold. Our data indicate that the HPF1 elements in the rat CYP2C genes have limited functional importance and that HNF-4 is not a major trans-activator for any of these genes.

Animals↗

[Restriction of medical criteria for disability pensions. Effects on the local level].

The objective of the analysis presented in this article is to assess the impact on a local level of the revised eligibility criteria for disability pensions in Norway. The setting was five mainly rural municipalities on the North-West coast of Norway and the city of Trondheim. The project was carried out as a document analysis of a sample of rejected applications for disability pensions, as they appeared in social security records from 1990/91, before the revision to the law, and from 1992, after the revision. Among a total of 146 such cases, 118 (81%) were available for the document analysis. Some national statistics were used for purposes of comparison. The percentage of rejected applications increased in all municipalities for both men and women. The new regulations accounted for 25% of the rejected cases. 31% of the rejected applications from women were based on the narrower criteria, as opposed to 17% of the men's. The impacts of the 1991 regulations have been considerable. The increased rejection rate adds to a falling rate of applications for disability pensions since 1989/90, accounting for an almost 50% reduction in the yearly incidence rate of granted pensions in Norway from 1989 to 1993.

Adolescent↗

The market is a strange creature: family medicine meeting the challenges of the changing political and socioeconomic structure.

This paper examines the extent to which family medicine is prepared to face today's political and socioeconomic trends. A modest assumption is that most countries will avoid the threats of food and energy crisis, environmental disasters, social collapse and even wars. Given that privilege, family medicine is faced with recent trends of market liberalism throughout the world, giving rise to new perspectives of economic prosperity, as well as widening gaps between the rich and affluent, and a growing number of unemployed, poor, and 'marginalized'. The recent UN World Summit for Social Development in Copenhagen highlighted the fact that poverty and long-term unemployment is becoming a permanent problem even in the rich world. The distinction between rich and poor countries might be better understood as widening gaps between rich and poor people in both kinds of countries. The challenge to family medicine will be twofold: 1) To develop a broader understanding of the associations between social risk factors on a population level, and its clinical expressions in individual patients in terms of illness, sick role behaviour and manifest disease, as well as potentials for constructive coping; 2) To contribute to a universally available primary health care, meeting the needs also of those who are not in the best position to pay. We are reminded of the classic 1971 Lancet paper by Julian Tudor Hart on "The inverse care law", implying that "the availability of good medical care tends to vary inversely with the need for it in the population served". In a world plagued with unforeseen discontinuities, general practice will need to maintain its core of 'personal doctoring'. Meeting people at the primary care level provides unique opportunities of being sensitive and responsive also to unexpected changes in society, and in some areas even making contributions to the directions of change.

Developed Countries↗

Ischaemic heart disease mortality among men in Norway: reversal of urban-rural difference between 1966 and 1989.

OBJECTIVE: This study aimed to examine regional urban-rural differences in mortality from ischaemic heart disease, including sudden death of unknown cause (IHD/SUD) in Norway from 1966-89, for men and women aged 30-69 years. DESIGN: Analysis was based on vital statistics. Regional mortality rates were obtained by aggregating the 443 municipalities in Norway into urban, rural, and intermediate municipalities. SETTINGS AND SUBJECTS: Norway. RESULTS: In 1966-70 the age adjusted IHD/SUD mortality in the age group 30-69 years was higher in urban than in rural areas; for men by 31% (95% CI 27%, 36%) and for women by 28% (95% CI 19%, 36%). In 1986-89 the IHD/SUD mortality for men showed a reversed urban-rural gradient: it was 8% (95% CI 2%, 13%) higher in rural than in urban areas. The mortality rates for women were equal for both these aggregates. For men the results indicate that IHD/SUD mortality peaked first in urban municipalities and then, but at a lower level, in rural areas. For women there was a substantial decline in IHD/SUD mortality between 1966 and 1989, but an actual peak could not be demonstrated in any of the three aggregates during the period. The decline in IHD/SUD mortality among women was steepest in urban municipalities and least noticeable in rural municipalities, but the decline tapered off towards the end of the study period. CONCLUSION: The results confirm a phase-shifted peak in IHD/SUD mortality, which began in towns and ended in rural areas, and provides clues to the main underlying factors in the IHD epidemic at the population level.

Adult↗

Transactivation of the rat CYP2C13 gene promoter involves HNF-1, HNF-3, and members of the orphan receptor subfamily.

The rat CYP2C13 gene (2C13) encodes one of the constitutive male forms of cytochrome P-450 that are involved in steroid metabolism. In addition to being developmentally regulated, the expression of 2C13 is restricted to the liver and suppressed by the female pattern of growth hormone (GH) secretion at the transcriptional initiation level. In this study, we show that the liver-specific expression, but not the regulation by GH, can be reconstituted with 117 bp to 2 kb of 2C13 5' flank. Transactivation of the 2C13 promoter requires both HNF-1 and HNF-3 and is influenced by members of the orphan receptor subfamily of transcription factors. Although HNF-4, ARP-1, EAR-2, and COUP-TF bind to the 2C13 promoter in vitro, overexpression of EAR-2 and COUP-TF, but not of HNF-4 or ARP-1, results in the potentiation of the HNF-3- and HNF-1-supported activity in non-liver cells.

Animals↗

[Physician and expert--a conflict situation? General practitioners work with disability pension's errands in a time of restraint policy].

OBJECTIVE: To study how general practitioners perceive their role and conduct their work as certifying physicians for patients applying for disability pension, with emphasis on effects of the revision of the law in 1991 which narrowed the medical criteria for eligibility. DESIGN: Personal in-depth interviews, tape recorded for qualitative analysis. SUBJECTS AND SETTING: 24 general practitioners in the city of Trondheim and rural communities in the county of Møre og Romsdal. OBSERVATIONS: Attitudes and behaviour varied considerably: On one side "the patient's advocate" strived for what he considered to be the best overall result for his patient--as opposed to "the consultant", who regarded himself as neutral and loyal to the policy makers. Narrowing the medical eligibility criteria for disability pension was perceived as reducing the doctor's influence on the outcome of an application. Many "consultants" welcomed the revision. Some "advocates" sought to counteract the loss of influence on the patient's situation through various coping strategies related to the medical certificate. Others intensified the search for alternative solutions to the patient's problems. A third strategy implied leaving the "advocate's" involvement in favour of a more disengaged role in order to make ideals meet with reality. CONCLUSIONS: Many certifying physicians seem to have been under considerable pressure, owing to the conflicting interests of patients and authorities, and we ask whether, under such conditions, the typical doctor tends to adopt a more "bureaucratic" and less "hippocratic" role.

Attitude of Health Personnel↗

[Restrictions in connection with disability pensions--physicians' view on the revised legislation].

In 1991, the Norwegian legislation on disability pensions was revised, narrowing the medical criteria for eligibility. From a questionnaire answered by 66 primary health care physicians attending a course in Oslo in October 1992, data were collected on doctors' attitudes and expectations regarding the revised legislation. The physicians did not believe that refusing a higher percentage of applications for disability pension would bring many applicants back to paid employment. The majority believed that lower expenditure on disability pensions would be reflected in a corresponding increase in other public expenditures. Despite this, half of the participants welcomed the revision of the law.

Adult↗