Precision tests of quantum mechanics.
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Biomedical subjects
Publications and source records attributed to S Weinberg.
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Twenty temporomandibular joints (TMJs) were operated on for the correction of arthrographically confirmed internal derangements using a modified preauricular approach. Postoperatively, three of the 20 patients tested exhibited auriculotemporal syndrome as deduced from a starch-iodine test. The manifestation was subclinical and consisted of sweating only over the distribution of the auriculotemporal and great auricular nerves in response to a gustatory stimulus. The response was variable from patient to patient.
Prevention of nosocomial urinary tract infections by iontophoresis is addressed. An iontophoretic generator was used to provide microamperage (10 to 400 microA) to vials containing either synthetic urine or supplemented synthetic urine. Bacteria were added to vials, and parameters of growth, bacterial killing, and multiple electrode materials were examined. Escherichia coli and Proteus species were both inhibited and killed at various microamperages and with several electrode types, the most efficient being gold-gold as the anode-cathode combination. Klebsiella pneumoniae in supplemented synthetic urine was least inhibited in growth, and higher microamperage (200 to 400 microA) was most effective in killing the bacteria. Bacterial growth reduction and killing were directly related to increasing microamperage and were inversely related to bacterial concentration.
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The case of a newborn girl with two mandibular incisor natal teeth and bilateral mandibular odontogenic harmartomas is presented. The hamartomas were evident as pedunculated masses on the posterior mandibular gum pads. The natal teeth were extracted at birth, and the hamartomas were excised at 5 months of age. Microscopic investigation of the hamartoma demonstrated the presence of all odontogenic tissues with the exception of an enamel organ. In addition, there was a strong family history of natal teeth, which may suggest a hereditary basis for the development of the odontogenic hamartoma.
A case of arthrogryposis multiplex congenita involving the temporomandibular joint is reported. This is only the second reported case in which surgery was used in an attempt to alleviate the limited mandibular opening that may be associated with this uncommon condition. The clinical findings at the time of surgery differed significantly from those classically associated with other joints afflicted with this condition, suggesting that a different pathophysiologic mechanism may be involved.
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A historical review of temporomandibular joint (TMJ) surgical meniscal repositioning procedures is presented, and three operations that are currently used to manage this problem are compared and contrasted. Each operation produces iatrogenic deviations in intra-articular anatomy and retains the potential to create significant alterations in TMJ biomechanics. Meniscocondylar plication has been performed on 84 patients (89 joints) with arthrographically confirmed internal derangement of the TMJ. A 90.7% success rate was achieved. The operation is technically facile, surgically uncomplicated and clinically effective. It should rank as a justifiable and viable alternative to those operations that are presently being performed to treat patients with internal derangement of the TMJ.
Twenty-eight patients with post-whiplash temporomandibular joint (TMJ) symptoms were assessed. Internal derangements were seen arthrographically in 22/25 patients. These observations were confirmed in the 10 patients who elected to have surgery.
The first case of osteoblastoma of the mandibular condyle is reported. The clinical, radiographic and histologic features of this benign neoplasm are described and the differential diagnosis is discussed.
2 cases of oral submucous fibrosis have been reported. In each case, the diagnosis was confirmed histologically, and the treatment instituted was identical. Excision of buccal fibrotic bands was carried out, with subsequent placement of skin grafts. The patients were followed postoperatively to monitor results and particularly, to screen for malignant changes. The literature concerning oral submucous fibrosis is reviewed.
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Conventional mediastinoscopy has a small but definite morbidity and mortality. Our continuing study was done to determine whether needle aspiration during mediastinoscopy is a safe and reliable procedure. In 14 consecutive patients having mediastinoscopy, needle aspiration biopsy was also done. There was a 100% correlation between diagnosis made by needle cytology and the final diagnosis, with neither false-positive nor false-negative results. This correlation was only 75% in the forceps biopsy group. In 90% of the cases, the cytopathologist correctly identified the final cell type. There were no complications, even in cases of superior vena caval (SVC) obstructions. The distinct advantages of the technique include high specificity, better tissue sampling, immediate availability of results, reduced morbidity, expanded indications in SVC syndromes, and higher yield than conventional punch biopsies.
Anesthesia was induced in 42 adults with thiopentone 3-7 mg/kg i.v. and maintained with isoflurane at a constant inspired concentration of 1-2%. After 30 min of hemodynamic stabilization with continuous muscle relaxation and an absence of surgical stimulation, each patient was randomly assigned to one of four metocurine dosage groups: I - control (n = 11); II - 0.2 mg/kg (n = 10); III - 0.3 mg/kg (n = 10); and IV - 0.4 mg/kg (n = 11). There were no significant hemodynamic changes in Groups I or II. In Groups III and IV mean arterial pressure (MAP) decreased 32% and 26% respectively, and systemic vascular resistance (SVR) decreased 42% and 36%, respectively (P less than 0.01). In Group IV, an increase of 24% in cardiac output was also significant (P less than 0.05). These results, especially in Group IV patients, stand in marked contrast to the lack of hemodynamic effects produced by metocurine during balanced anesthesia.