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Biomedical subjects

S Walter

Publications and source records attributed to S Walter.

At least 289 records · Page 16Linked to original sources
PubMed1979

Changes in the forced expiratory spirogram in young male smokers.

Forced expiratory spirograms and peak expiratory flow were measured in 102 resident male medical students (60 nonsmokers and 42 smokers). Forced vital capacity; forced expiratory volume in 1 sec; forced expiratory volume in 1 sec expressed as a percentage of forced vital capacity; forced expiratory flows between 80 and 70 per cent, between 55 and 45 per cent, between 30 and 20 per cent, and between 15 and 5 per cent of the forced vital capacity; forced expiratory time for the last 0.5 liter of the forced vital capacity; and maximal mid-expiratory flow were determined from the forced expiratory spirogram. Peak expiratory flow, all forced expiratory flows (except the forced expiratory volume in 1 sec), and the ratio of forced expiratory volume in 1 sec to forced vital capacity were significantly lower, and forced expiratory time for the last 0.5 liter of the forced vital capacity was significantly higher in the heavy smokers (those who had smoked a lifetime total of more than 10,000 cigarettes) than the nonsmokers. The light smokers (those who smoked a lifetime total of fewer than 10,000 cigarettes) had values between those of nonsmokers and the heavy smokers. Thus, a definite dose-related response to smoking was seen. Flows at lower lung volumes showed greater percentage changes than flows at higher lung volumes. The forced expiratory flow between 30 and 20 per cent of the forced vital capacity was the most sensitive test for detecting abnormality in smokers. Among heavy smokers, 58 per cent had abnormally low forced expiratory flow between 30 and 20 per cent of the forced vital capacity, whereas only 47 per cent had abnormally low ratio of forced expiratory volume in 1 sec to forced vital capacity, and 32 percent had abnormally low maximal mid-expiratory flow. The results show that even subjects with short smoking histories may have changes in pulmonary function that probably reflect narrowing of small airways. Moreover, these changes can easily be detected by simple tests, such as evaluation of a forced expiratory spirogram.

Adult↗
PubMed1979

Prostatism. I. The correlation between symptoms, cystometric and urodynamic findings.

One hundred and seven consecutive patients referred with symptoms of bladder outlet obstruction were studied using cystometry and combined pressure-flow-electromyographic investigation. The symptoms of infravesical obstruction were not statistically significantly correlated to the hydrodynamic documentation of increased bladder outlet resistance as judged by maximum flow rate and the calculated urethral resistance. Irritative symptoms such as frequency, nocturia, urgency and urgeincontinence were statistically significantly correlated to the presence of detrusor hyperreflexia. The functional disorder bladder neck dyssynergia was encounterd in 5% of the patients (95% confidence limits 1-10%). This diagnosis cannot be made by conventional urological investigations. It is concluded that objective demonstration of infravesical obstruction is mandatory in the selection of patients with symptoms of lower urinary tract dysfunction for surgery on the prostate or the bladder neck.

Adult↗
PubMed1979

Bladder function in urologically normal middle aged females. A urodynamic and radiological investigation.

The bladder function was studied in 15 urologically normal females over 40 years of age. They volunteered for this study which consisted of urodynamic studies and lateral micturition cystourethrography. The data are presented in tables. There are only small differences in the urodynamic parameters between this material and a material of women under 40 years of age. It is clearly demonstrated that a gynaecological cystocele tells little or nothing about the bladder function or bladder support. None of the cystometrograms showed uninhibited detrusor contractions. It is underlined to repeat the micturition studies several times in order to obtain a voiding event which the subject recognizes as normal.

Adult↗
PubMed1978

The influence of wound drainage on the infection rate in kidney transplant patients.

The frequency of wound infection was studied in 92 patients who had received cadaver kidneys. Wound drainage was performed in 26 patients and not performed in 66 patients. Wound infection was found in 31% of the wounds with drainage and in 14% of wounds without primary drainage. The results were compared with the frequency of 34% infected wounds in a previous report where wound drainage was performed routinely. It is advised that, when possible, wound drainage should be avoided.

Drainage↗
PubMed1978

Diagnostic catheterization and bacteriuria in women with urinary incontinence.

The risk of single catheterisation in females with urinary incontinence and/or genital prolapse was studied in patients referred for urodynamic examination. Two hundred and eighty-six catheterisations were performed followed by a mid-streem specimen 1 week later, and in 31 of these the initial specimen contained more than 10(5) bacteria. Following catheterisation bacteriuria occurred in 5 (2%) of the patients with initially sterile urine. The phenomenon of "asymptomatic bacteriuria", "transient significant bacteriuria" and "bladder defence mechanism" is discussed. The risk of introducing urinary tract infection in urodynamic studies is low.

Adult↗
PubMed1978

Detrusor hyperreflexia in female urinary incontinence treated pharmacologically.

Detrusor hyperreflexia was found in 54 patients or 14.6% of 369 consecutive patients referred for urinary incontinence and/or genital prolapse during a 2-year period. The dominant symptom was urge incontinence. The urological investigation consisted of a medium fill water cystometry in the supine position. 20 patients (37%) suffered from cerebral or pyramidal nervous disorders. The treatment of choice was pharmacological with parasympatholytica, methantheline bromide (Banthine). The follow-up examinations performed in 33 patients after 6 months treatment showed an improvement rate of 82%. The importance of performing a cystometry in all female patients referred for urinary incontinence is stressed.

Adult↗
PubMed1978

Bladder base insufficiency. Radiological, urodynamic, and clinical aspects.

Among 420 consecutive patients referred for voiding cystourethrography 26% presented the picture of bladder base insufficiency (b.b.i.). The examination was carried out as a colpo-cysto-urethrography. A urodynamic and gynecological examination was performed in each patient. The characteristic morphological features were: Anterior and inferior displacement of the bladder neck and a pointed bladder base. The position and form of the vagina was normal. Radiological signs of detrusor function were weak and opening of the bladder neck was characterized by funneling. Urodynamically the patients with b.b.i. showed low opening and low detrusor contraction pressures. The flows were highly varying. Very high flows were seen in a few patients but the more common pattern was slightly reduced maximum flow rates. Opening of the internal urethral orifice is known to be caused by detrusor contraction. Closing is passive, caused by elastic properties in the tissues. In b.b.i. intravesical pressures during micturition were low and radiological signs of detrusor contraction were weak, indicating that the bladder neck was easily opened. This, on the other hand, means that the bladder neck was insufficiently closed during bladder reservoir function, and may explain the main symptom, stress incontinence, which was present in 84% of the patients. The underlying pathology in anatomical support and suspension of the bladder base is discussed.

Adult↗
PubMed1977

Repeated, rapid fill CO2-cystometry.

114 consecutive patients were subjected to double, rapid fill CO2-cystometry. In 106 the two cystometries were of the same type, although several cystometric values changed statistically significantly. In eight patients the two cystometrograms were of a different type with uninhibited detrusor contraction in one but not in the other. A possible explanation for this is discussed.

Carbon Dioxide↗
PubMed1977

Detrusor hyperreflexia and bacteriuria.

In a retrospective study of 579 patients with cystometrically proven detrusor hyperreflexia bacteriuria was correlated to the commonly accepted etiologies, and to the duration and amplitude of the uninhibited bladder contractions. Blood flow in the bladder wall may be reduced by increased intravesical pressure due to detrusor hyperreflexia, and it has been suggested that a resulting weakening of antibacterial defense mechanisms is responsible for the majority of urinary tract infections in these patients. We have not been able to confirm this hypothesis. We found no statistically significant difference between the incidence of bacteriuria in patients with low amplitude and short duration of the bladder contractions and in patients with high amplitude and long duration of the uninhibited bladder contractions.

Bacteriuria↗
PubMed1977

The effect of blood-transfusions on renal allograft survival.

The relation between previous bloodtransfusions and renal allograft survival was studied retrospectively in 88 patients, who had been transplanted for the first time. The allograft survival rate was higher in the group who had received bloodtransfusion than in the group who had not. This difference was significantly greater when considering patients who had not previously been pregnant, e.g. patients without previous stimulation of the immuno system. The material shows no difference in allograft survival between previously transfused and non transfused patients, when considering age, sex or disease of kidney. In this retrospective study it is concluded that previous transfusions improved the prognosis of the transplantation. A prospective study has yet to be done, in order to enlighten the influence of various other factors on the allograft survival rate such as length of period or uraemia and of dialysis.

Adolescent↗