Search PubMed⌕ Search

Biomedical subjects

S Waga

Publications and source records attributed to S Waga.

At least 163 records · Page 9Linked to original sources
PubMed1983

Familial intracranial aneurysms: report of four families.

The authors describe eight cases of familial intracranial aneurysms occurring in four families. In the literature reviewed, familial aneurysms have different characteristics in that the incidence of the anterior communicating aneurysms is lower and that of the middle cerebral aneurysms is somewhat higher, and the age of patients at diagnosis is often younger. Although the number of patients is few, our study does not support these characteristics. A family history of intracranial aneurysms should include such high-risk factors as polycystic kidneys, coarctation of the aorta, fibromuscular dysplasia, and other connective tissue disorders.

Adult↗
PubMed1983

Intracerebral hemorrhage remote from the site of the initial neurosurgical procedure.

Four cases of intracerebral hemorrhage remote from the site of the initial neurosurgical procedure are presented. Two of the four patients had preoperative hypertension. Possible mechanisms are discussed, and labile hypertension and unstable blood pressure during the perisurgical period may be contributory. Clinical awareness of this rare but potential complication is essential to early diagnosis and treatment. Difficulty in awakening from anesthesia and the development of new neurological deficits not attributable to the operative site are the most important keys to early diagnosis. Computed tomography is the diagnostic method of choice.

Adult↗
PubMed1983

Monocyte function in idiopathic nephrotic syndrome in childhood.

The monocyte function of 112 specimens from 42 children with idiopathic nephrotic syndrome (INS) aged from 2 to 17 years was studied by the methods of nitroblue tetrazolium (NBT) reduction, phagocytosis of immunobeads (IB) and yeast cells, chemotaxis and acid alpha-naphthyl acetate esterase (ANAE) staining. The dissociation between phagocytosis and chemotaxis was observed in the fresh cases of steroid sensitive INS and in the cases of steroid non-sensitive INS. In the fresh cases of steroid sensitive INS, NBT reduction and phagocytosis were increased, but chemotaxis was decreased. In the cases of steroid non-sensitive INS, the phagocytosis of IB was decreased, but chemotaxis was increased. These findings suggest a different pathogenesis between steroid sensitive and steroid non-sensitive INS. The dissociation between phagocytosis and chemotaxis may be explained by the alteration of the surface receptors of monocyte and by lymphokines.

Adolescent↗
PubMed1983

Cerebral chromoblastomycosis complicated by meningitis and multiple fungal aneurysms after resection of a granuloma. Case report.

Cerebral chromoblastomycosis is a rare intracranial lesion. This lesion was found in a 23-year-old man, who presented with right proptosis and fainting attacks. Computerized tomography revealed a moderately enhanced irregular mass in the right frontal region. Angiography disclosed that the mass was avascular. At surgery, a hard elastic avascular tumor was totally removed piecemeal. Histological diagnosis was a granuloma of fungal origin. Characteristic brown pigments in the hyphae of fungus in the granuloma strongly suggested that the fungus was chromoblastomycosis. The postoperative course was complicated by meningitis and rupture of fungal aneurysms. The patient remained vegetative and died 2 1/2 years later. The literature on such fungal aneurysms is briefly reviewed; no previous case of fungal aneurysms associated with cerebral chromoblastomycosis could be found.

Adult↗
PubMed1983

[Clinical evaluation of cefpiramide in pediatrics].

Cefpiramide (CPM) is a newly developed cephalosporin. Clinical studies on this drug were carried out and the results were as follows; Forty-three patients (purulent lymphadenitis 2, cellulitis 2, purulent otitis media 1, purulent tonsillitis 3, acute bronchitis 2, pneumonia 22, bronchiectasis 1, urinary tract infection 10) were treated with CPM, in doses of 20 approximately 82 mg/kg divided 2 approximately 4 times per day for 3 approximately 11 days intravenously. The overall efficacy rate was 83.7%. As to adverse reaction, 4 cases, which includes 3 cases of diarrhea and 1 case of exanthema, were observed. Abnormal laboratory data noted were liver dysfunction in 3 cases (6.8%), and eosinophilia in 2 cases (4.5%).

Adolescent↗
PubMed1983

[Clinical studies of T-1982 (cefbuperazone) in pediatric field].

T-1982 (cefbuperazone) is a newly developed cephamycin. Clinical studies on this drug were carried out and the results were as follows: Eighteen patients (pneumonia 13, purulent tonsillitis 1, acute bronchitis 1, cellulitis 1, urinary tract infection 2) were treated intravenously with daily 27.4-100.2 mg/kg of T-1982 in 3-4 divided dose for 3-6.7 days. The overall efficacy rate was 94.4%. No adverse reactions were observed. Abnormal laboratory data noted were liver dysfunction in 1 case (4.8%), eosinophilia in 2 cases (9.5%), and anemia in 1 case (4.8%).

Anti-Bacterial Agents↗
PubMed1982

Dandy-Walker cyst associated with occipital meningocele.

Two cases of Dandy-Walker cyst associated with occipital meningocele are presented. Only 9 cases with such association have been described in the literature. In our patients computed tomography clearly demonstrated direct communication of a posterior fossa cyst with an occipital meningocele at one end and with the fourth ventricle at the other. Occipital meningocele might simply be an expression of increased intracystic pressure in Dandy-Walker cyst in embryonic life, or such association might suggest its morphogenetic situation during embryogenesis.

Brain↗
PubMed1982

Glossopharyngeal neuralgia of traumatic origin.

Glossopharyngeal neuralgia of traumatic origin is very rare. Two interesting cases are presented, one with a skull fracture involving the jugular foramen and the other associated with an operation for an acoustic tumor. Carbamazepine gave good results and both patients improved within 24 hours. The glossopharyngeal and vagal nerves might have been injured in the region of the root entry zone giving rise to the neuralgia. Pertinent literature is briefly discussed.

Adult↗
PubMed1982

Persistent intraventricular hematoma following ruptured aneurysm.

It is well known that intraventricular hematomas disappear within three weeks, as documented by computed tomography (CT). Recently we encountered a patient with an intraventricular hematoma, caused by rupture of an aneurysm of the anterior communicating artery, that persisted as a visible lesion on CT scans two months following the hemorrhage.

Cerebral Hemorrhage↗
PubMed1982

Diencephalic syndrome of emaciation (Russell's syndrome).

Diencephalic syndrome of emaciation (Russell's syndrome) characteristically presents with the symptoms of marked emaciation in spite of normal linear growth and marked increased of serum growth hormone in infancy and early childhood. It is usually caused by a low-grade glioma, most often an astrocytoma, of the anterior third ventricle including the optic nerve and chiasm. Usually it is not associated with von Recklinghausen's neurofibromatosis. We describe two unusual cases of diencephalic syndrome; one case was caused by a low-grade astrocytoma involving the anterior third ventricle associated with neurofibromatosis, and the other by a malignant astrocytoma of the anterior third ventricle.

Astrocytoma↗
PubMed1982

[Penetration of cefotiam dihydrochloride into cerebrospinal fluid (author's transl)].

It is well recognized that only very low concentration of antibiotics is obtained from cerebrospinal fluid (CSF) despite its high blood concentration. It has been attributed to the blood-brain and blood-CSF barriers. Penetration of CTM into CSF was studied in 7 patients. Two of them were complicated with septic meningitis, and others were not infected. CTM was administered intravenously and samples were obtained from both serum and CSF from 15 minutes to 4 hours for determination of concentration of the antibiotics. In 2 patients with meningitis, the peak level of CTM in CSF after intravenous injection of 2 g and 1 g of CTM was 197 mcg/ml (46% of peak serum concentration), and 17.3 mcg/ml (38% of peak serum level), respectively. In noninfected patients the peak level of CTM in CSF after intravenous injection of 1g of CTM was from 0.3 mcg/ml to 1.9 mcg/ml (0.84% approximately 3.64% of peak serum concentration). We conclude that the percent penetration of CTM into CSF increases in the presence of the inflamed meninges and that prophylactic dosage of CTM for postoperative meningitis will be intravenous administration of 2 g of CTM in adults.

Adult↗
PubMed1982

[Stenosis of the intracranial internal carotid artery by a craniopharyngioma: report of a case].

Stenosis of the intracranial internal carotid artery by other tumors than meningiomas and pituitary adenomas is a rare occurrence. We present here a case with craniopharyngioma, which developed severe stenosis of the intracranial internal carotid artery 7 years following partial removal and irradiation. This severe stenosis of the intracranial internal carotid artery would result from combination of compression of the arterial walls against the surrounding bony structures and radiation effect on the arterial walls. A 29-year-old male was found to have a craniopharyngioma, which was treated by partial removal in 1971. He had suffered bilateral optic atrophy, right homonymous hemianopsia and panhypopituitarism. Angiography revealed elevation of the A-1 and opening of the carotid siphon on both sides. He had a course of 5,000 rads of Lineac irradiation in 1972. He showed no clinical improvement. He became totally blind in 1976. He was admitted again in 1979, because of left sided weakness and Korsakoff syndrome. Examination disclosed that there were bilateral optic atrophy, left hemiplegia with hyperreflexia and pathological reflexes, hypesthesia in the left side of the face and Korsakoff syndrome, chiefly consisting of confabulation. Angiography showed that the right internal carotid artery was markedly elevated and stenosed. The left internal carotid artery was elevated and the left A-1 was stenotic. The territory of the left distal anterior cerebral artery was filled from the anterior falx artery of the ophthalmic artery. The right A-1, M-1 and M-2 were filled through the left A-1. The territory of the right anterior cerebral artery was filled through the right posterior pericallosal artery and that of the right middle cerebral artery was partly filled through the posterior temporal and occipito-parietal arteries of the posterior cerebral artery. A right superficial temporal-middle cerebral artery bypass surgery was performed with some clinical improvement.

Adult↗
PubMed1981

Aneurysm on a persistent hypoglossal artery.

The authors report a patient with saccular aneurysm on a left persistent hypoglossal artery who suffered subarachnoid haemorrhage from an aneurysm of the right distal anterior cerebral artery. A review of the literature emphasizes the rarity of the occurrence of an aneurysm on a persistent primitive hypoglossal artery itself.

Angiography↗
PubMed1981

Chondrosarcoma of the ethmoid sinus extending to the anterior fossa.

A 27-year-old women with chondrosarcoma of the ethmoid sinus extending to the anterior fossa had initial symptoms of blurred vision on the left and slight proptosis. Neuroradiological examination, however, disclosed that the tumor extended not only to the anterior cranial fossa, but also to the orbit, nasal cavity, and maxillary sinus. It is difficult to predict the biological behavior of chondrosarcoma by means of histological examination. The effectiveness of radiotherapy, chemotherapy, or both is also a matter of controversy. Clinical aspects of chondrosarcoma are briefly discussed.

Adult↗