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Biomedical subjects

S V Chandra

Publications and source records attributed to S V Chandra.

At least 127 records · Page 7Linked to original sources
PubMed1975

Manganese induced hepatic lesions in carbon tetrachloride pretreated rats.

Manganese sulphate (6 mg/kg) was administered intraperitoneally daily for 30 days in carbon tetrachloride pretreated rats. Histological and histochemical studies in liver tissue revealed extensive damage to hepatic parenchyma in these rats as compared to lesions produced by manganese sulphate alone. These findings suggest that workers, with liver dysfunction ergated in manganese industry may be more susceptible to the toxic effects of this metal.

Administration, Oral↗
PubMed1975

Thorium induced testicular changes in rats.

Daily intraperitoneal administration of thorium nitrate produced progressive morphological and biochemical alterations with the increase in thorium concentration in rat testis. The degenerative changes in the seminiferous tubules increased with the duration of treatment and after 90 days calcification occurred in about 25% of the tubules and in the connective tissue of the tunica albuginea. The activity of adenosine triphosphatase and alkaline phosphatase increased markedly as a result of thorium administration. An attempt has been made to interrelate histopathological and enzymatic changes and the metal concentration in the testicular tissue.

Adenosine Triphosphatases↗