The authors studied the effect of LRH and TRH on HGH in 10 adolescent schizophrenic boys and 9 age-matched normal boys. Before antipsychotic treatment, LRH and TRH induced a marked rise in hGH in 8 of 10 patients and 4 of 6 patients, respectively. No effect on HGH was observed in the normal controls. After 3 months of treatment with chlorpromazine, thioridazine, or haloperidol, LRH failed to induce a rise in HGH in 5 of the 6 patients tested, but TRH induced a significant rise in HGH in 3 of 4 patients tested. The authors postulate that these results indicate a dysfunction in the mechanism regulating HGH secretion in schizophrenia.

Adolescent↗

PubMed1979

Further studies on cell-mediated immunity to myelin basic protein in schizophrenic patients.

Cell-mediated immunity (CMI) toward myelin human basic protein (HBP) was studied in 19 chronic drug-free schizophrenic patients and in 30 patients with primary affective disorders receiving psychoactive drugs, 74% of the schizophrenics showed an inhibition of macrophage migration, whereas only one patient from the affective group showed such a response. These results indicate that drugs are not responsible for the appearance of CMI to HBP in schizophrenics. One out of 9 ECT-treated patients developed a CMI to HBP.

Adult↗

PubMed1979

The biphasic effect of gradually increased doses of diazepam on prolactin secretion in acute schizophrenic patients.

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Acute Disease↗

PubMed1979

Bipolar depression (manic-depressive disease) in early adolescence.

Bipolar Depression is rare in early adolescence. Since only rare cases were described in the literature, every case is important. In this article we described three cases of Bipolar Depression who were hospitalized in our Adolescent Unit during the past three years. All of them started at age 13--14. It is important to diagnose this illness in order to administer the required treatment in the acute phase and preventive treatment afterwards. Our experience indicates that treatment for early adolescents is identical with treatment for adults and calls for the same dosage.

Adolescent↗

PubMed1978

Movement therapy with psychotic adolescents.

Non-verbal behaviour has long been a focus of attention in the psychiatric literature. Furthermore, most psychiatric hospitals make use of non-verbal therapies in their milieu programmes. These include art, music and dance therapy, and related to the latter, movement therapy. This paper represents the beginning of an attempt to assess more scientifically the effectiveness of movement therapy. It describes the movement therapy programme on our adolescent unit, the evolution of a measuring scale and compares three groups of patients: (A) a group which had received individual therapy; (B) A group which had received group therapy; and (C) a control group. The results tend to confirm the effectiveness of movement therapy for psychotic adolescents.

Adolescent↗

PubMed1978

The heart image as a model to internal-organ body image.

We show that there is indeed an internal-organ body image: the heart. Using questionnaires and drawings, we compared a group of healthy subjects, a group of acutely ill cardiac patients and a group of chronic cardiac patients. A constant body image emerged which was not influenced by heart disease. It seems to us that this approach can serve as a model of further studies of internal-organ body image.

Adult↗

PubMed1976

Cell-mediated immunity to human myelin basic protein in schizophrenic patients.

Cell-mediated immune response to myelin human basic protein was studied by the macrophage migration inhibition test in patients suffering from schizophrenia. Eighteen out of 32 patients with chronic schizophrenia demonstrated human basic protein-induced inhibition of the migration index, while 4 out of 41 acute schizophrenics showed an inhibition of macrophage migration.

Acute Disease↗

PubMed1976

Attitudes of the Israeli adolescent to the mentally ill and their treatment.

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Adolescent↗

PubMed1976

Dimensions of adolescent in-patient behaviour.

140 adolescent in-patients were rated on a 40-item, 3-point behaviour scale. A principal component analysis was made and two major factors emerged which accounted for 44.3% of the total variance: one factor related to level of functioning and overinhibition and the other to aggression. A graphical representation of the patients with respect to the above factors provided important information as regards prognosis and clinical diagnosis. As in previous related studies (Klein & Davis (1969)), the validity of clinical diagnostic categories was confirmed and information on the process of making these diagnoses was provided.

Adolescent↗

PubMed1975