The role of the Israel Psychiatric Association at a time of health reform.
Explore the source record for details and available documents.
Ethics, Medical↗
Biomedical subjects
S Tyano
Publications and source records attributed to S Tyano.
Platelet monoamine oxidase activity in neuroleptic-naive schizophrenic patients: lack of influence of chronic perphenazine treatment.
We investigated the possible relationship between schizophrenia, neuroleptic treatment, and platelet monoamine oxidase (MAO) activity. Platelet MAO activity was similar in neuroleptic-naive schizophrenic patients and healthy controls and was not affected by chronic (10-week) perphenazine treatment. A relationship between platelet MAO activity and central disturbances in schizophrenia remains uncertain.
Adult↗
Cultural effects on eating attitudes in Israeli subpopulations and hospitalized anorectics.
We assessed eating attitudes and body image using the Eating Attitudes Test-26 (EAT: Garner & Garfinkel, 1979) and a 17-item body image scale in Israeli Jewish female high school populations in five distinct residential settings (kibbutz, moshav, city, and 2 different boarding schools); in five ethnically distinct Arab female high school populations (Muslim, Christian, Druze, Circassian, and Bedouin); and in a group of hospitalized adolescent girls with anorexia nervosa. We hypothesized that the attitudes of the adolescent females most exposed to Western body shape ideals and simultaneously undergoing role conflict between traditional and modern images of the female role would most resemble attitudes of anorectics. This was partly supported by the findings. Ethnic differences also emerged in attitude toward food. All the Arab populations except the Circassian showed strong Western influences in their attitudes toward eating and body image and thus may well be prone to epidemics of anorexia and similar eating disorders in the near future. Kibbutz girls were most similar to the anorectic group.
Adolescent↗
Child and adolescent psychiatry and aggression.
Explore the source record for details and available documents.
Adolescent↗
[Postpartum blues and depression].
Explore the source record for details and available documents.
Depression↗
Reduced total complement haemolytic activity in schizophrenic patients.
Serum concentrations of the third and fourth components of the complement system and total complement haemolytic activity were measured in 167 psychiatric patients. Total complement haemolytic activity was decreased in chronic schizophrenic patients as compared to healthy controls and bipolar patients. The relatively diminished total haemolytic activity was not attributable to drug treatment. It is not clear if the reduced total haemolytic activity is an epiphenomenon or related to the involvement of an autoimmune process in the pathophysiology of schizophrenia.
Autoimmune Diseases↗
Fears of death in suicidal and nonsuicidal adolescents.
Suicidal, psychiatric, and normal adolescent girls and boys, ages 15-17 years, participated in a study on five types of death fears. A mixed within-between multivariate analysis of variance (5 factors x 3 groups) yielded significant interactive effects of indicating that there were different profiles of fears among the three groups: Relative to the other groups, suicidal adolescents displayed little differentiation between facets of fear, with differences in the magnitude of fear limited to the intrapersonal facets. Correlates of fear varied between groups: Fear was positively correlated with suicidality in normal subjects, negatively correlated with suicidality among suicidal ones, and unrelated to suicidality in the psychiatric group. It is suggested that fear of death is processed and experienced differently by suicidal and nonsuicidal adolescents to serve as a facilitator or inhibitor of suicidal behavior.
Adolescent↗
Cytokine production in anorexia nervosa.
The capacity of peripheral blood mononuclear cells (PBMCs) of anorexia nervosa (AN) patients to produce interleukin-1 (IL-1), interleukin-2 (IL-2), and interleukin-3-like activity (IL-3-LA) was studied. A significantly lower (-49%, p < 0.005) capacity to synthesize IL-2 and an almost significantly impaired ability (-35%, p = 0.058) to release IL-3-LA by PBMCs of AN patients was found, as compared with cells of the control group. IL-1 production, either spontaneous or after stimulation with lipopolysaccharide (LPS), did not differ significantly between AN patients and healthy subjects. The lessened capacity to produce IL-2 was accompanied by an enhanced stimulatory activity of the patient sera on the production of this cytokine by PBMCs of healthy subjects. It is therefore suggested that the serum of AN patients contains a stimulatory factor or factors for cytokine production that compensates for the lower production of cytokines by AN PBMCs. Such a compensatory mechanism may explain why AN patients do not have an higher susceptibility to infections.
Adolescent↗
The Ganser syndrome in two adolescent brothers.
The Ganser syndrome is rare in children and adolescents. Two cases of Ganser syndrome in adolescent brothers, both of whom developed the syndrome while in jail and awaiting trial, are presented. Both brothers subsequently developed signs and symptoms indicative of affective disorder. The differential diagnosis and the management of these two patients are discussed in the light of the nosological controversies surrounding this clinical entity.
Adolescent↗
Body image of achondroplastic children before and after leg elongation.
Body image disturbance was studied in 6 achondroplastic children before and after surgical leg elongation (Wagner's procedure) using Fisher's Draw-a-Person Test and the Body Cathexis Test, as well as on another group of 6 achondroplastic children who had undergone the same procedure several years earlier. These groups were compared with 12 healthy control children. Gross disturbance of body image was present before the operation with a substantial improvement after the procedure. However, even years after the surgical procedure there still exists a difference in body image between the control-normal group and achondroplastic adolescents.
Achondroplasia↗
[Anorexia nervosa in a young diabetic].
Coexistence of diabetes mellitus and anorexia nervosa has been noted in the past 2 decades. The nature and treatment of diabetes offer numerous opportunities for the anorectic patient to lose weight. Improper adjustment of the insulin dose, failure to inject insulin, clandestine vomiting and failure to provide urine samples allow the anorectic diabetic to achieve morbid weight loss. The treatment of patients with both conditions is difficult; behavioral management combined with psychotherapy was found to be most effective. An illustrative case is presented.
Adolescent↗
Neuroendocrine response to trihexyphenidyl in depressed patients.
The effect of a single dose (10 mg P.O.) of trihexyphenidyl (THP) on plasma cortisol, growth hormone (GH), and immunoreactive beta-endorphin (ir-beta-EP) was studied in seven major depressed patients and seven controls. GH secretion was suppressed (34-41%) by THP in both groups. THP did not affect cortisol secretion in depressed patients and controls. An increase (18%; p less than 0.05) in plasma ir-beta-EP levels was detected in the healthy subjects only. The results of this study do not support the hypothesized altered responsiveness to anticholinergic provocation in major depression. The inhibitory activity of THP on GH secretion indicates the involvement of the cholinergic system in the regulation of GH release in humans.
Adult↗
Elevated plasma immunoreactive beta-endorphin in anorexia nervosa.
Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), and 17-beta estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-beta-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-beta-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.
Adolescent↗
Cognitive modifiability of adolescents with schizophrenia: a research note.
It is well documented that schizophrenic patients suffer from numerous cognitive defects. In a preliminary investigation, the Learning Potential Assessment Device was used under controlled conditions to examine the cognitive modifiability of institutionalized adolescent schizophrenics (N = 12) and a contrast group of adolescents with severe conduct disorders (N = 10). Feuerstein's theory of structural cognitive modifiability was thus applied in assessing potential for change. Results are encouraging in that there was evidence of the modifiability of the experimental subgroups of both the schizophrenic and conduct disorder groups.
Adolescent↗
[Neuropsychiatric symptoms in systemic lupus erythematosus].
Involvement of the central nervous system in systemic lupus erythematosus is frequent (50-66%). Its manifestations may be either neurological, psychiatric or both. The psychiatric syndrome may appear without physical symptoms, or may accompany severe systemic involvement. In either case psychiatric diagnosis is quite difficult and consequently treatment is often controversial. We review current knowledge and present the case of an 18-year-old male which illustrates the complexity of both diagnosis and treatment of the syndrome.
Adolescent↗
[Violence, suicide and the media].
Explore the source record for details and available documents.
Adolescent↗
[AIDS and psychiatry].
Explore the source record for details and available documents.
Acquired Immunodeficiency Syndrome↗
Platelet peripheral benzodiazepine receptors in repeated stress.
[3H]PK 11195 binding to platelet membranes and plasma stress hormones were studied in soldiers at the beginning of a parachute training course, following 6 days of preparatory exercises, and after the fourth actual parachute jump. A slight reduction (15%; NS) in the number of peripheral benzodiazepine receptors (PBR) was detected at the end of the exercise period, prior to the first jump. Reduced (26%; P less than 0.05) density of PBR was observed immediately after the repeated actual jumps. Equilibrium dissociation constants were not affected by the stressful situation. Plasma cortisol and prolactin levels remained unaltered during the entire study period.
Adolescent↗