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Biomedical subjects

S Turgut

Publications and source records attributed to S Turgut.

30 records · Page 2Linked to original sources

Postoperative hypertension after radical neck dissection.

Postoperative hypertension after radical neck dissection was detected in 20.2% of 109 neck dissections in our department between 1989 and 1993. It was probably caused by carotid sinus denervation and appeared after the vasodilation generated by anesthesia had subsided. If postoperative hypertension was encountered after the first operation, the risk of such hypertension after surgery on the contralateral side significantly increased.

Adult↗

Substrate recognition domains as revealed by active hybrids between the D-arabinitol and ribitol transporters from Klebsiella pneumoniae.

Two new genes, dalT and rbtT, have been cloned from the dal operon for D-arabinitol and the rbt operon for ribitol uptake and degradation, respectively, in Klebsiella pneumoniae 1033-5P14, derivative KAY2026. Each gene codes for a specific transporter which, based on sequence data, belongs to a large family of carbohydrate transporters which constitutes 12 transmembrane helices. DalT and RbtT show an unusually high similarity (86.2% identical residues for totals of 425 and 427 amino acids, respectively). This allowed the construction of DalT'-Rbt"T and RbtT'-Dal'T crossover hybrids by using a natural restriction site overlapping Met202. This site is located within the large cytoplasmic loop which connects the putative helices 6 and 7 and in particular the amino- and the carboxy-terminal halves of the transporters. Both hybrids have close to normal transport activities but essentially the substrate specificities and kinetic properties of the amino-terminal half. This result localizes essential substrate binding and recognition sites to the amino-terminal halves of the proteins in this important class of carbohydrate transporters.

Amino Acid Sequence↗

Rhinolithiasis.

Rhinoliths are mineralized masses located in the nasal cavity. In this report, 12 patients with rhinolithiasis who were operated at the 2nd ENT Clinic of Ankara Numune Hospital are presented. The most frequently seen symptom is nasal obstruction, which has been seen in 9 patients. The disease most frequently seen in association with rhinolithiasis is chronic sinusitis. All masses have been extracted intranasally.

Adolescent↗

Isolated sphenoid sinusitis.

Isolated sphenoid sinusitis is a relatively rare clinical entity and can cause severe complications. Diagnostic nasal endoscopy using Hopkins telescopes and coronal and axial paranasal-sinus CT made the diagnosis of the sphenoid sinus disease easier. Eight out of 221 patients with paranasal sinus infection refractory to medical treatment--and treated surgically at the 2nd ENT Clinic of Ankara Numune Hospital between 1990-1995--had isolated sphenoid sinus infection. The most common symptom was headache felt in the retro-orbital region. Surgical procedure was intranasal endoscopic approach to the sphenoid sinus. The symptoms of the patients with isolated sphenoid sinusitis were completely resolved after surgery. As the literature is reviewed, it is concluded that endoscopic approach to the sphenoid sinus disease is the most appropriate method of surgery in order to reduce intra-operative morbidity and mortality.

Adolescent↗

Diagnosis and treatment of lingual thyroid: a review.

Lingual thyroid is a rare developmental anomaly. It occurs because of the defective descent of thyroid tissue through the thyroglossal duct to its normal pretracheal position. In this study, two patients who presented with a mass in the oropharynx, finally diagnosed as lingual thyroid are presented, and the literature is reviewed. The masses were 3 x 2.5 x 1.5 cm and 3.5 x 3 x 3 cm in size. The diagnosis was based on the clinical features, fine needle aspiration biopsy, laboratory tests and radiographic imaging studies. The first case was treated medically with thyroxine. No treatment was given for the second case because of the patient's refusal. Both cases have not required additional therapy so far.

Adult↗

Endoscopic anatomic distances on the lateral nasal wall.

OBJECTIVE: Functional endoscopic sinus surgery has become popularized during the last decade all over the world. Knowledge about the intricate anatomy of the nasal cavity, the ethmoid labyrinth, and related structures is of vital importance for the endoscopic sinus surgeon to avoid probable complications. This study was undertaken to provide a set of reference distances to the endoscopic surgeons. METHOD: In this surgical anatomic study, the distances of special anatomic landmarks from the anterior nasal spine were measured during the endoscopic dissection. The procedure was performed in 50 cadavers and measurements were done by the use of straight surgical guide under endoscopic vision. CONCLUSIONS: Optimum attention should be concentrated on vital structures such as optic nerve and internal carotid artery at posterior rhinobasis after approximately 75 mm. Surgical distances of critical anatomic landmarks on the lateral nasal wall from anterior nasal spine should be kept in mind during surgical interventions.

Adult↗

Distribution of facial nerve in parotid gland: analysis of 50 cases.

The purpose of the present study is to reduce the postoperative morbidity related to facial paralysis during parotid surgery and to layout the different characteristics related to intraparotideal distribution and anastomoses of the facial nerve in our community. We also report new variations in the facial nerve branchings that have not been previously published. In this paper, facial nerves from 48 cadavers and 2 patients of which 45(90%) were males and 5(10%) were females; 26(52%) being right and 24(48%) being left facial nerves were put forward. Their photographs were taken and the diagrams of intraparotideal distributions of each facial nerve were drawn. The intraparotideal configuration of the facial nerve was evaluated in 5 types. Twenty-four% of the facial nerves had no anastomoses (Type I); 12% had a ring-like shape anastomosis between the buccal and the zygomatic branches (Type II); 14% anastomoses were between the buccal and the other branches in a ring-like shape (Type III); 38% of the facial nerves had multiple complex anastomoses and were named as multiple loops (Type IV); 12% had two main trunks (Type V). Of the bilateral cadaver dissections, the facial nerve distribution in 9(47.3%) were bilaterally the same and in 10(52.7%) main trunks were different. A facial nerve trifurcation composed of two main trunks were also established. There were no statistical differences between branching of the facial nerves in the right and left side of the faces.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Correlation between temporal bone pneumatization, location of lateral sinus and length of the mastoid process.

The relationship between temporal bone pneumatization and the location of the lateral sinus and length of the mastoid process was investigated in 60 fresh frozen adult temporal bones, by plain X-rays, computed tomography and surgical dissection including otomicroscopic findings. Temporal bone pneumatization was classified as small, moderate and large. After drilling, the shortest distances between the middle fossa dura and mastoid tip representing the mastoid length and between the sigmoid sinus and posterior border of external auditory canal were measured and compared to the degree of pneumatization. The distances in the specimens with pathological eardrum and adhesions in the middle ear were compared to the ones without gross pathology. The length of mastoid process was significantly shorter in specimens with small pneumatization than those with large (Mann Whitney P less than 0.001). The specimens with a pathological eardrum and middle ear adhesions had a significantly shorter mastoid length than those without gross pathology. There was no significant difference between degree of pneumatization and the shortest distance between sigmoid sinus and external auditory canal (Mann Whitney P greater than 0.05). It is demonstrated that the 'under-developed' mastoid process can be a consequence of hampered pneumatization.

Adult↗

Causes of facial nerve paresis after translabyrinthine surgery for acoustic neuroma.

Forty-six consecutive video-recorded translabyrinthine operations at Gentofte Hospital, for tumors of 5 to 25 mm, were investigated for possible damage to the facial nerve from cauterization, suction, stretching, pushing, and other instrumental trauma at the following regions: fundus, internal meatus, porus, cerebellopontine angle, and brain stem. House-Brackmann grading of the postoperative facial nerve function was determined from the patient records for the 1st, 3rd, and 10th days and 3 months and 6 months postoperatively, as well as the final status. Suction on the nerve seems to be the most important factor for perioperative facial nerve damage. The most common site of damage was the porus region. This investigation shows thermic drilling lesions to be very relevant. There was no correlation between the degree and character of damage and the postoperative facial nerve function. In eight patients we cannot explain the postoperative facial palsy.

Facial Nerve↗

[Microorganisms isolated from chronic suppurative otitis media and their antimicrobial sensitivities].

In this study mycologic and bacteriologic cultures were made in 100 patients who had chronic suppurative otitis media. We observed 58.8% pure, 35.3% mixed growth (more than one bacteria or bacteria and fungus) in the cultures. In pure cultures, we found mostly Proteus sp., S. aureus and Pseudomonas sp. respectively. In 134 bacteriologic cultures most frequently isolated bacteria was S. aureus (36.6%). In Sabouraud agar, we found mostly Aspergillus sp. and Candida sp. (28.6%). In antimicrobial sensitivity test, gram negatives were found to be sensitive mostly to ofloxacin (73.5%), pseudomonas was found to be sensitive mostly to tobramycin (70%). In the staphylococci the antimicrobic which had the highest sensitivity rate was gentamicin (75.5%), but at the same time we observed 24.5% resistance to this antimicrobic agent. Following this respectively, ofloxacin 71.4% sensitivity 4.1% resistance, cefuroxime 69.4% sensitivity 10.2% resistance rate were detected.

Anti-Bacterial Agents↗