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Biomedical subjects

S Teramoto

Publications and source records attributed to S Teramoto.

At least 523 records · Page 29Linked to original sources
PubMed1976

Metabolic fate of ethylenethiourea in pregnant rats.

Metabolic fate of ETU was investigated in the rats administered orally 100 mg/kg of C14-ETU on the twelfth day of gestation. ETU was absorbed readily from the gastrointestinal tract and passed away from the whole body tissues including the fetus rapidly. Only the exception was the thyroid gland and the radio-activity was accumulated in the gland. Most of the administered activity (80.2%,4,5-C14-ETU) was eliminated into the urine in 24 hr and the tissues (including the fetus) levels of radioactivity from 2-C14-ETU reached maximal within 2 hr and fell down to negligible levels by 24 hr. Radiocarbon(s) of 4,5-C14-ETU was expired as radioactive carbon dioxide and was incorporated into the serum and fetal cell constituents (crude protein fraction), but that of 2-C14-ETU was neither expired or incorporated into the cell constituents. From the fetus extract ETU and several radioactive metabolites were detected.

Absorption↗
PubMed1976

Study of hemodynamic changes with oxygen inhalation in VSD associated with pulmonary hypertension.

Pre- and postoperative pulmonary hemodynamic changes were studied in 28 cases with ventricular septal defect, in whom pulmonary-systemic blood pressure ratio was more than 70%. Pp/Ps decreased and Qp/Qs increased in majority of cases and Rp/Rs decreased in all cases after 100% oxygen inhalation. In survivors, Rp/Rs decreased to under 0.5 and Qp/Qs increased to more than 2.0 after oxygen inhalation or radical operation. In nonsurvivors, Rp/Rs decreased but stayed over 0.5, and Qp/Qs increased but stayed under 2.0. It is emphasized that when Rp/Rs falls down to under 0.5 after oxygen inhalation, it will be an enough indication for operation even pulmonary hypertension is so advanced in the ventricular septal defect.

Blood Pressure↗
PubMed1976

Total correction of Ebstein's anomaly by replacement with a biological aortic valve without plication of the atrialized ventricle.

For the surgical management of Ebstein's anomaly, the preferred operation will be Hardy's procedure, which preserves the patient's valve. However, we have encountered 3 cases of this disease in which the downward displacement of the tricuspid valve was so severe and the functioning right ventricle was so small that Hardy's method could not be adapted without causing tricuspid regurgitation and making the right ventricular chamber more narrow. We treated these patients by replacing the tricuspid valve with an inverted aortic valve with a stent and not plicating the atrialized ventricle. The results have been proved satisfactory through about 7 years' follow-up, suggesting that our technique will be remarkably effective as a radical corrective operation for Ebstein's anomaly with severe intracardiac abnormalities.

Adolescent↗
PubMed1975

Consturction of new right ventricle on the epicardium: a possible correction for underdevelopment of the right ventricle.

By covering almost the entire right ventricular free wall and the anterior wall of the left ventricle with a Teflon cloth, we constructed a new chamber on the epicardium of a canine heart. An aortic homograft with the aortic valve was anastomosed to the right atrium as an inlet of this chamber. Another aortic homograft was sutured to the main pulmonary artery as an outlet. Pressure produced in this chamber ranged 25 to 55 mm. Hg and its first derivative was 450 to 1,870 mm. Hg per second. Thus this chamber had an excellent capability of epicardium will yield more physiological benefits to patients with an agenetic or hypoplastic right ventricle than do the current surgical procedures, in which a conduit is interposed between the right atrium and the main pulmonary artery. The procedures proposed could pressurize the pulmonary circulation and produce a pulsatile flow.

Animals↗