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Biomedical subjects

S Takagi

Publications and source records attributed to S Takagi.

At least 541 records · Page 30Linked to original sources

Oro-maxillofacial development in patients with Turner's syndrome.

Detailed oro-maxillofacial studies using dental casts, pantomograms and cephalograms were performed in 28 patients with Turner's syndrome and compared statistically to the results from 23 normal short children. Small tooth crown size, short tooth roots and advanced dental age were characteristic of patients with Turner's syndrome. However, the incidence of peg shaped teeth, malocclusion, high arched palate and congenital anodontia were not characteristic of patients with Turner's syndrome. The coronal arch width (C.A.W.) and basal arch width (B.A.W.) were greater and the coronal arch length (C.A.L.) and basal arch length (B.A.L.) were less in patient's with Turner's syndrome. These data indicate underdevelopment of the maxilla in the forward direction forming the wide-, flat-shaped facial characteristic of patients with Turner's syndrome.

Adolescent↗

Neurological manifestations in chronic alcoholics.

One hundred and twenty-two chronic alcoholics were examined neurologically after more than 14 days of abstinence. A high frequency of the following was noted: abnormal smooth pursuit eye movement, hyperreflexia, snout reflex, incoordination, and signs suggesting peripheral neuropathy. Some significant mutual correlations among these neurological signs were noted, although they characteristically appeared independently and no patient showed typical clinical features of classical alcoholic neurological diseases, such as Wernicke-Korsakoff syndrome. Only abnormal smooth pursuit eye movement and incoordination showed significant correlation with nutritional status and these signs were more frequently present in the poor nutritional status group. There seemed to be a correlation between abnormal smooth pursuit eye movement and cortical atrophy on head CT scan. The possible pathogenetic mechanisms underlying these neurological abnormalities are discussed.

Adult↗

[Evaluation of the atrial contribution to ventricular filling in patients with DDD pacemakers].

To evaluate the usefulness of physiologic cardiac pacing, the trasmitral flow velocity was recorded using the pulsed Doppler method combined with 2-D echocardiography in 14 patients in whom a DDD pacemaker was implanted. DDD pacemakers were programmed to atrioventricular (AV) sequential pacing with AV intervals of 50, 100, 150, 200 and 250 msec, and VVI pacing modes at a heart rate of 70 bpm. The time-velocity integral (TVI) of the left ventricular (LV) inflow curve was obtained by digitizing the outline of the tracings and expressed in the percentage of that of AV sequential pacing with AV interval of 150 msec (the percent LV filling volume). The percent LV filling volume was 75% for 50 msec, 89% for 100 msec, 96% for 200 msec and 90% for 250 msec of an AV interval in AV sequential pacing. It was significantly smaller at AV intervals of 50, 100 and 250 msec than at an AV interval of 150 msec. It was significantly smaller (68%) in VVI pacing than at AV intervals of 100, 150, 200 and 250 msec in AV sequential pacing. The left atrial (LA) contribution to LV filling was assessed in terms of the fraction of TVI during LA contraction to that during total LV filling at the optimal AV interval (A/Fmax). The optimal AV interval was defined as the interval at which the maximum LV filling volume was achieved in individual patients. The A/Fmax showed a positive correlation with the percent increase of LV inflow volume, with conversion from VVI to AV sequential pacing with the optimal AV interval. It also showed a positive correlation with age. These results suggested that the LV inflow volume was greater in AV sequential pacing with the optimal AV interval than in VVI pacing, especially in patients with a large A/Fmax. In conclusion, pulsed Doppler echocardiography could be a useful, non-invasive technique to determine the indications for implanting a DDD pacemaker and the optimal AV interval in patients in whom DDD pacemakers are implanted.

Adult↗

[Monostotic fibrous dysplasia in the parietal bone: a case report].

In this paper a case of monostotic fibrous dysplasia in the left parietal bone is described. This 51-year-old female was admitted to our hospital for a head injury on January 12, 1983, and a flat, painless hump (7 X 7cm) was incidentally found in the left parietal region. Plain x-ray film of the skull showed a multicystic lesion with slightly sclerotic margin in the left parietal bone, and outward bulging of the outer table without destruction of the inner table in tangential view. CT scan at the level of bone window clearly demonstrated the same abnormality and intradiploic mass separated by some bony septums. Angiography revealed no positive findings, but RI bone scan (99m Tc) showed an abnormal uptake in this lesion. On February 1, 1983, operation was performed to verify the nature of the lesion and for relief of the left-sided headache. Post operative course was uneventful. Histological findings of this mass were of inactive fibrous dysplasia with fibrous tissue replacing the normal bone and surrounded by island or scorlled edge of bones. Monostotic fibrous dysplasia in the cranial vault is rare. It is often possible to make diagnosis in this disease on the clinical course, plain x-ray film and CT scan showing cystic findings and outer table bulging, and RI scan demonstrating abnormal uptake.(ABSTRACT TRUNCATED AT 250 WORDS)

Contusions↗