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Biomedical subjects

S Sakuma

Publications and source records attributed to S Sakuma.

At least 361 records · Page 20Linked to original sources
PubMed1983

[Detection of cancer by nuclear magnetic resonance imaging].

Nuclear magnetic resonance (NMR) imaging for medical diagnosis is rapidly approaching a time of widespread clinical trials. It may ultimately give images a clear as those obtained with computed tomography with a potential for defining tissue chemistry. Perhaps the method can be as free from hazard as is visual observation. The ability to produce coronal and sagittal as well as axial transverse images directly is shown to have important implications for precise lesion assessment. NMR imagings at high magnetic fields demonstrate excellent image quality and high spatial resolution. The variety of sequences possible with NMR allows a choice of images to reflect varying degrees of proton density and blood flow, as well as tissue spin-lattice (T1) and spin-spin relaxation (T2) times.

Brain Neoplasms↗
PubMed1983

Computer-assisted conformation radiotherapy system. An application of CT.

A newly developed computer-assisted conformation radiotherapy system is presented and its accuracy discussed in an experimental investigation and a clinical study. The system consists of a CT scanner, radiotherapy treatment planning system and linear accelerator. These systems are smoothly interconnected. Planning of multi-split conformation radiotherapy can be performed accurately and rapidly. Opening of the multi-split collimators was accurately controlled by computer on the basis of the treatment planning data. Dosage distributions in the irradiated body reconstructed using transit x-rays are also presented. As a simple back-projection method was used for calculation, the reconstructed dosage distribution resembling that of beam-focus radiography. Further investigation is required to complete this technique and to use it for the verification of radiotherapy treatment planning.

Computers↗
PubMed1983

[Monitoring of I-125 contamination in vivo by analysis of the saliva].

Monitoring of workers who did iodination of protein was performed for 5 months on 10 persons. The activity in saliva was evaluated following the sun peak method by using a NaI(Tl) detector and a 400-channel analyzer. The concentration of 125I in saliva ranged 4.65 +/- 2.1 cBq (1.26 +/- 0.57 pCi)/ml to 135 +/- 2.7 cBq (36.45 +/- 0.73 pCi)/ml and the average was 20.8 +/- 1.9 cBq (5.62 +/- 0.51 pCi)/ml. The ratio of concentration in saliva to used activity ranged (2.2 +/- 0.64) X 10(-9) to (3.6 +/- 0.073) X 10(-8) and the average was (8.1 +/- 1.1) X 10(-9). The thyroidal uptake per iodination ranged 146 Bq (3.94 nCi) to 2700 Bq (72.9 nCi). The ratio of the uptake to the used activity ranged from 7.3 X 10(-5) to 5.4 X 10(-6). The thyroidal absorbed dose ranged from 378 microGy (37.8 mrad) to 4740 microGy (474 mrad). Monitoring of 125I-in saliva was proved to be a useful method to investigate the internal contamination of workers doing iodination.

Environmental Exposure↗
PubMed1981

Origin of malignant adenocarcinoma cell line induced by retrovirus-like particles from DMBA rat mammary tumors.

Intraperitoneal inoculation of neonate Sprague Dawley rats with cell-free extracts containing retrovirus-like particles from DMBA-induced rat mammary tumors resulted in a fivefold increase of benign mammary neoplasias in the survivor animals, in comparison to the spontaneous tumor incidence rate. In addition, four animals developed metastasizing abdominal adenocarcinomas. The ascitic cells of one of the abdominal tumors were established as a permanent tissue culture line (HH-1). After subsequent animal passage, cells of the permanent line HH-9 clone 14 showed increased malignancy manifested by the number of takes per animals injected, and by the number of remote metastases observed.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1981

[Basic examination on the energization of experimental animal feces by methane fermentation (author's transl)].

Basic experiments of methane fermentation of livestock excreta have been reported by many investigators, yet there has been no report of experiments of methane fermentation of experimental animal feces. We considered that it would be feasible to gasiby experimental animal feces by methane fermentation. In this report, methane gas fermentation of rat feces is studied. The results are summarized as follows: 1. Methane fermentation of rat feces yielded, under the conditions described, 220-4231 of gas per kg of organic matter. 2. Decomposition ratio of BOD removal volume in organic matter was 50-60% when the fermentation condition was optimum. 3. The volume of gas from BOD removal volume in organic matter was 500-600ml/g. 4 Methane gas contents in the gas generated from the feces ranged from about 55-60%. 5. COD removal ratio was above 80%, and BOD removal ratio above 90%. From these data, the authors conclude that under the optimum conditions, described sufficient methane gas can be obtained from rat feces by methane fermentation.

Animals↗