Search PubMed⌕ Search

Biomedical subjects

S Poulsen

Publications and source records attributed to S Poulsen.

At least 127 records · Page 7Linked to original sources
PubMed1979

Comparison of different measurements of development of plaque and gingivitis in man.

The purpose of the present study was to compare efficiency of measurements commonly used to study the development of plaque and gingivitis in short-term clinical trials. Data from a recent experiment on the effect of mutanase on accumulation of plaque and development of gingivitis were used. Efficiency was compared using 1) level of significance and 2) minimum number of individuals necessary to obtain a statistically significant result at a given level of significance and with a given power of the test. Of all the measurements used, the gingival exudate measurement was the most efficient. Among the nonparametric indices, Plaque Index was the most efficient, especially on proximal surfaces in the mandible. Reduction of the scales for the nonparametric indices from a four-point scale to a two-point (dichotomous) scale slightly reduced experimental efficiency.

Chewing Gum↗
PubMed1979

Retention of fissure sealant in primary second molars after 6 months.

Low retention of fissure sealant in primary teeth could be due to insufficient moisture-control in young children. In the present study 10 primary maxillary second molars and 29 primary mandibular molars were sealed using rubber dam while their contralateral teeth were sealed using cotton rolls. No difference in the retention of the sealant could be demonstrated.

Child, Preschool↗
PubMed1978

Comparison of blind and non-blind assessments of occlusal sealant retention.

A comparison was made of scoring the retention status of BIS-GMA occlusal sealants 5 years after they had been placed, according to a non-blind and blind method of identification of teeth that had been sealed. Subjects were 175 children ages 15--18. One examiner made all the assessments. Retention of sealant was classified as all present, partly missing or all missing. There was 90.5% complete agreement between non-blind and blind examinations in scoring the retention status of 893 occlusal sites. Essentially no difference in agreement was found between sites on maxillary and mandibular teeth nor according to sites in specific teeth. There was only a slight tendency to classify more sites as having sealant present at the non-blind examinations than at the blind examinations, 56.7% and 55.1%, respectively. These findings would seem to indicate that whether examinations are done blindly or non-blindly is of minor importance in making an accurate assessment of sealant retention.

Adolescent↗
PubMed1978

Effect of professional toothcleansing every third week on gingivitis and dental caries in children.

A previous paper reported on the 1-year effect on dental caries and gingivitis of biweekly professional toothcleansing. The purpose of this study was to evaluate the influence of a change from 2 to 3 weeks in the interval between the professional toothcleansings during the 2nd year. The DMFS increment during the 2nd year did not differe significantly between the experimental and control groups. The plaque and gingival indices, although increased during the 2nd year, were still significantly lower in children subjected to the 3-weekly cleansing than in children in the control group.

Child↗
PubMed1978

An evaluation of Knutson's formula for estimating age-specific DMF teeth.

The present study evaluated a formula suggested by Knutson for obtaining an age-specific estimate of mean DMFT in a population on the basis of the age-specific percentage of individuals with 1 or more DMFT. A total of 149 previously collected age-specific data sets from low-flouride areas in the U.S.A. were used, and the two parameters K and B were estimated using the method of weighted least squares. The analysis showed that the formula could be used with good accuracy for certain restrictions of age (5--11 years) and percentage of individuals with 1 or more DMFT (less than or equal to 70%).

Adolescent↗
PubMed1978

Retention and effectiveness of a chemically polymerized pit and fissure sealant after 2 years.

Following a single application of a chemically polymerized fissure sealant (Concise Enamel Bond System) 60% of the sealants were present after 2 years of examination. The effectiveness of the treatment was highly significant and the caries reduction, irrespective of the sealant status, was found to be about 50%. The caries reduction was 98% in sealed pairs where the material was fully retained.

Child↗
PubMed1978

Reduction of the formation of dental plaque and gingivitis in humans by crude mutanase.

The effect of a Trichoderma harzianum enzyme preparation containing mutanase (alpha-1,3 glucan glucanohydrolase) on plaque accumulation and composition and on occurrence of gingivitis was assessed in 20 persons in a double-blind cross-over investigation. The enzyme preparation was administered in chewing gum. Two test periods of 1 week were preceded by scaling and cleansing of the teeth, oral hygiene instruction, and controlled hygiene for at least 3 weeks. Oral hygiene measures were discontinued during the test periods, while the persons chewed six pieces of chewing gum per day, one half using enzyme-containing gum, and the other half using placebo gum. The test periods were identical, only enzyme gum was used instead of placebo, or vice versa. Evaluations of plaque and gingivitis showed that less plaque had accumulated and less gingivitis developed during the enzyme than during the placebo period, but bacteriologic studies of interproximal plaque did not reveal differences that could explain the clinical findings. Treatment with the enzyme preparation caused some local side effects, but no primary skin irritation, delayed hypersensitivity, nor anti-enzyme IgE was detected in any of the persons.

Clinical Trials as Topic↗
PubMed1978

Effect of dextranase on plaque formation and caries development in the rat.

Plaque formation and caries development were studied in 0-M rats fed Diet 2000 and infected with S. mutans 6715 and fecal flora from older caries-active rats. Merck dextranase, Beckman dextranase or Beckman glucanase 447 were administered singly or in combination to groups of 12 rats either as an addition to the diet or as a "mouthwash" twice daily, 5 per week. All enzymes studied were associated with significant inhibition of both plaque formation and caries development, especially on the buccal and lingual surfaces.

Animals↗
PubMed1978

The effect of supervised tooth cleansing every second week on dental caries in Danish school children.

The purpose of the present study was to determine the effect of a program of regular plaque control carried out by a group of school children, supervised and assisted by dental personnel. Approximately 200 children 5--13 years of age were randomly assigned to two groups. Children in the experimental group performed supervised toothbrushing every second week during the school year, using a disclosing solution. Following this, a disclosing solution was reapplied and the remaining plaque removed by dental personnel. Both groups participated in fortnightly fluoride rinses, regular toothbrushing instruction and various educational activities. Mean dental caries increment at the precavitation level during the 2-year experimental period was 19 per cent lower in the experimental group than in the control group. At the cavitation level the difference was 17 per cent. None of these differences were statistically significant. The conclusion of the present study was that only limited effect of regular removal of dental plaque as performed by school children could be demonstrated.

Adolescent↗
PubMed1977

Retention and effectiveness of a single application of an adhesive sealant in preventing occlusal caries: final report after five years of a study in Kalispell, Montana.

The single application of a BIS-GMA adhesive sealant in Kalispell on a paired half-moouth basis and the annual monitoring of the sealed sites for five years is not a recommended preventive regimen. The study does proved information on the potential long-term in vivo retention of the sealant and its ability to prevent dental caries. The findings of this study clearly show that when this pit and fissure sealant is retained, its is effective in preventing caries in sealed tooth surfaces. Moreover, on occlusal surfaces, the usual susceptibility to decay is not altered by having been treated with a sealant that is not retained.

Adolescent↗
PubMed1976

The effect of professional toothcleansing on gingivitis and dental caries in children after 1 year.

The purpose of this study was to determine the effects of professional mechanical toothcleansing on plaque, gingivitis, and dental caries in young children with a high caries experience. Seventy-eight children, 7 years of age, were stratified according to presence or absence of smooth surface lesions on the permanent teeth and subsequently randomly assigned to an experimental group and a control group. The experimental group was given a thorough mechanical toothcleansing every 2 weeks. After 12 months a statistically significant difference in plaque accumulation and a minor difference in level of gingival inflammation could be demonstrated between the two groups. The incidence of dental caries in permanent teeth present at both examinations was 70% lower in the experimental group. The effect on permanent teeth erupting during the study and on primary teeth present at both examinations was not statistically significant.

Child↗
PubMed1976

Retention and effectiveness of a chemically polymerized pit and fissure sealant after 12 months.

The aim of the present study was to evaluate the retention and effectiveness of a bis-GMA type of fissure sealant which polymerizes after conventional mixing of the two catalyst/activator components (Concise Enamel Bond System). Unilateral sealing of homologous pairs of permanent first molars was carried out by a dental hygienist. Of the 451 sealed sites sealant was present in 73%, partly missing in 8%, and completely missing in 18% after 1 year. The effectiveness of the treatment in preventing occlusal caries was highly significant and the caries reduction was found to be about 70%. A strong relationship between status of sealant and occlusal decay was demonstrated. The shortcomings of the half-mouth design when evaluating sealants as a caries-preventive measure in public dental health programs are discussed.

Child↗