Search PubMed⌕ Search

Biomedical subjects

S Porat

Publications and source records attributed to S Porat.

71 records · Page 4Linked to original sources
PubMed1977

HLA B27 and ankylosing spondylitis in the Israeli population.

The distribution of 24 HLA antigens of the A and B loci was investigated in 38 Israeli ankylosing spondylitis (AS) patients of various ethnic origins. This was compared with the distribution in rheumatoid arthritis (RA) and osteoarthritis (OA), as well as in 456 controls representing the Jewish population and 260 controls representing the Arab population. Included in the study were Ashkenazi Jews and non-Ashkenazi Jews, as well as Moslem and Christian Arabs. The frequency of HLA B27 among AS patients (79 per cent) was significantly greater (P less than 10(-10)) than among the controls (three per cent). Ashkenazi Jews showed a higher relative risk than non-Ashkenazi Jews and Arabs. Six of the AS patients were offspring of consanguineous marriages, but this was not higher than expected and therefore no indication for rare recessive genes contributing to the disease could be demonstrated. This study confirms the association between AS and B27, and extends our knowledge to the heterogeneous population of Israel not previously investigated. A significant but weak association of B27 with RA was noted. No correlation of other HLA antigens with RA or OA was observed.

Adult↗
PubMedDate not supplied

Brucella arthritis of the sacro-iliac joint.

We are reporting a case of culture-proven brucella sacro-iliitis. The treatment included surgical drainage and curettage together with tetracycline and streptomycin. A five-year follow-up showed complete cure: the patient was free of symptoms, the sacro-iliac joint was normal and a serologic test negative. The diagnostic difficulties, the differential diagnosis and the appropriate treatment are also discussed in this paper.

Adult↗
PubMedDate not supplied

Fever following orthopedic operations in children.

One hundred fifty-three orthopedic operations in 129 children were analyzed for the significance of postoperative fever (POF) as a predictive factor for possible complications. In 72% of the operations, a temperature of greater than 37 degrees C was recorded. In 63 operations (41%), the temperature was greater than 38 degrees C. Sixteen children had positive clinical signs that might explain the fever, and all of them had a temperature of greater than 38 degrees C. Duration of operation of greater than 1 h, clubfoot releases, open reduction of fractures, and spine fusion operations gave higher incidences of POF. POF indicates a complication only when associated with positive physical findings. A postoperative temperature of greater than 38 degrees C, therefore, mandates repeated physical examination, which is the most reliable method of discovering the presence of complications.

Adolescent↗
PubMedDate not supplied

Assessment of bony bridge by computed tomography: experimental model in the rabbit and clinical application.

A bony bridge was created in the growth plates of young rabbits. Weekly computed tomography (CT) scanning was done in the axial (transverse) plane for 3 weeks. Transverse histological sections from the plate area were examined after 3 weeks. The CT image showed the exact location and extent of the sclerotic bony bridge. The area of the bony bridge as a percentage of the plate was measured from the CT image. Good correlation was found between the CT image and the histological section. This technique has been applied to children, and three such examples show accurate assessment of the growth plate.

Animals↗
PubMedDate not supplied

Functional results of operation in osteogenesis imperfecta: elongating and nonelongating rods.

Gait capacity, operative intervention, and complications of operation were evaluated in 20 patients with osteogenesis imperfecta (OI). Thirty-two Bailey-Dubow (B-D) rods and 24 nonelongating rods were used. Postoperatively, gait capacity improved in eight patients, regressed in three, and remained unchanged in nine. No preoperative ambulator regressed to a nonambulatory status. The Sillence disease type was not a prognostic indicator of giat capacity. The complication rate was 72% for the B-D rod and 50% for the nonelongating rod, although the percentage requiring reoperation was similar for both types of nails. There was no difference in longevity between the two nails.

Adolescent↗
PubMedDate not supplied

Equalization of lower limbs by epiphysiodesis: results of treatment.

Equalization of lower limb length was achieved by epiphysiodesis in 20 children. During the period under review the Phemister procedure was replaced by percutaneous epiphysiodesis, and orthoroentgenogram was superseded by computed tomography (CT) scanning. In five children with anisomelia, whose expected discrepancy was 4.5 cm, the results at maturity showed an average discrepancy of 0.7 cm. In 10 girls with limb-length discrepancy (LLD) caused by ischemic necrosis with congenital dislocation of the hip, the average LLD at maturity was 0.6, whereas the expected LLD was 4 cm. In five children with LLD caused by infection, the average discrepancy was 3.8 cm at the time of epiphysiodesis, whereas at maturity it was 0.5 cm. A good result was achieved in 90% of the patients. We recommend the Moseley straight-line graph, CT scanography, and percutaneous epiphysiodesis.

Adolescent↗
PubMedDate not supplied

The use of ultrasound in the diagnosis of atypical pathology in the unossified skeleton.

Three cases are presented: a congenital dislocation of the patella, a congenital dislocation of the radial head, and an epiphysiolysis of the distal humerus. In all three cases the pathology involved unossified parts of the skeleton poorly demonstrated by plain radiographs. Ultrasonography proved useful in diagnosis and treatment of these cases.

Bone Diseases, Developmental↗
PubMedDate not supplied

The use of restraint on patients in Israeli psychiatric hospitals.

This first-ever study of the use of restraint on psychiatric patients in Israel sought to determine the dominant motivations in the decision to use restraint, which patients were most likely to be restrained, and whether there was a consistent policy on the matter. A survey of the official records of every instance of restraint during one month in the closed wards of all government psychiatric hospitals, supplemented with interviews, revealed that 14.2% of the study population had undergone restraint. The declared reasons were conventional, i.e. violence, disturbed behaviour, etc. Undeclared was an interaction between patients and staff, both the most professional and the less skilled, which surprised the authors and requires more investigation. Some subgroups, e.g. women and certain immigrant groups, were restrained markedly more frequently than other groups. No consistency of policy was found. Overall, much of the restraint applied is deemed unnecessary and recommendations are made for its reduction.

Adult↗
PubMedDate not supplied

Complete duplication of an accessory first ray.

A case report of an accessory metatarsal located between the first and second metatarsals is presented. This rudimentary accessory ray caused a splay foot deformity that made it difficult for the patient to walk comfortably in shoes. In reviewing the literature, there has been very little reported on the complete duplication of a metatarsal, as described by Venn-Watson. The authors will discuss the proper treatment of, and review the classifications associated with, this deformity.

Child↗
PubMedDate not supplied

Congenital dislocation of the knee.

Congenital dislocations of the knee (CDK) are rare, occurring 40-80 times more rarely than congenital dislocation of the hip (CDH). In a multicentric study of the European Paediatric Orthopaedic Society, 56 cases of CDK were found in 46 babies. Many other malformations associated with CDK were noticed, and muscular abnormality was always found at the knee. According to the classification of Leveuf, three grades have to be considered: grade 3, or complete dislocation, was the most frequent. At birth, treatment consisted of physiotherapy with rigid splint. Twenty-four patients with CDK have been treated only by the conservative technique. Operations were performed according to the abnormalities of the extensor apparatus: a progressive release and lengthening of the quadricipital tendon was necessary in all cases. In all forms of treatment, the range of the knee flexion was 120 degrees. Only two children had a bad result because of unstable knees. Results were always better with conservative treatment.

Female↗
PubMedDate not supplied

Critical analysis of results in club feet treated surgically along the Norris Carroll approach: seven years of experience.

We have used the Norris Carroll approach to the surgical release of resistant club feet for the last 7 years. Critical analysis of 33 idiopathic club feet, after an average follow-up of 4 years, by clinical and radiological methods showed 82% satisfactory results and 18% unsatisfactory. The results indicated a trend toward limited plantar flexion in these feet, as well as mild supination that disappeared with walking. The advantage of the dual skin incision approach is easy access to both plantar medial and posterolateral structures. The calcaneocuboid joint is released and emphasis is put on release of the lateral tether.

Arthroplasty↗
PubMedDate not supplied

Prevention of peripheral nerve entrapment following extensive soft tissue injury, using silicone cuffing: an experimental study.

A semirigid silicone cuff was investigated in rats to prevent scar entrapment of the sciatic nerve. Scar was induced by crushing or burning the surrounding muscles. On one side, the nerve was covered by a longitudinally split semirigid silicone tube. On the other side, the same procedure was done without silicone coverage of the nerve. At different time periods the animals were sacrificed and the nerve with surrounding tissues examined. The protected nerve was found gliding freely during mobilization of the limb. The blood supply to the nerve was maintained through the split in the silastic cuff by formation of new mesoneurium. On the control side, the nerve was surrounded by a fibrous tissue in various stages of maturation depending upon the time postinjury. The nerve structure showed reduced vascularity and progressive degenerative changes of the axons. Clinical tests on the silicone cuff method are proposed fo selected patients with extensive soft tissue injury around nerves.

Animals↗
PubMedDate not supplied

Abdominal flap to the avulsed leg.

One-stage surgery in which an abdominal flap is used for coverage of the leg in the presence of fractured femur is suggested in cases of avulsion injury of the leg with multiple fractures. The efficacy of this concept was proved by experimental work.

Abdomen↗
PubMedDate not supplied

Popliteal pterygium associated with complete amelia of upper limb: early surgical treatment.

We report a 5-year clinical follow-up and the operative details of a patient who was born with popliteal pterygium and ipsilateral upper amelia. There were no craniofacial, genitourinary, or other extremity abnormalities, other than severe pes equinovarus. At age 3 weeks, excision of the pterygium and partial release of the hind foot had accomplished a significant but incomplete release of the knee contracture. At age 11 months, a second release of the pterygium, combined with complete reconstruction of the foot, accomplished a straight limb. Presently at the age of 5, the boy has 40 degrees limitation to full extension at the knee but walks, runs, and behaves like all the other children in the nursery school. This combination of congenital malformations and early surgical intervention has never been described in the orthopedic literature.

Abnormalities, Multiple↗