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Biomedical subjects

S Noda

Publications and source records attributed to S Noda.

At least 163 records · Page 9Linked to original sources
PubMed1993

Chest x-rays before ophthalmic surgery.

We retrospectively reviewed clinical records and preoperative chest x-ray films of 636 patients who had been admitted for ophthalmic surgery in 1990 and 1991. In our hospital, a preoperative chest roentgenogram routinely was examined for each patient. A total of 228 patients (35.8%) had an abnormal preoperative result. These abnormalities were more frequent in patients older than 40 years of age than in younger patients. Pulmonary fibrosis and calcification were the most common abnormal findings. Also, we noted that 202 patients (31.8%) had a chronic, previously known, or suspected, finding, and 26 patients (4.1%) had a new or unsuspected finding. The surgery was postponed or canceled in five patients (0.8%) because of the abnormal x-ray results.

Adolescent↗
PubMed1993

Pseudoretinitis pigmentosa in patients with systemic lupus erythematosus.

A 42-year-old woman and a 62-year-old man with systemic lupus erythematosus (SLE) had bilaterally mottled retinas with spots or clumps of pigment. Their electroretinographic responses were subnormal. Their fundi resembled those of patients with retinitis pigmentosa. The fundus lesions of our patients may have resulted from vascular occlusion associated with SLE.

Adult↗
PubMed1993

Intraocular lymphoma invades the optic nerve and orbit.

A diagnosis uveitis OS was made in a 54-year-old woman; this was resistant to corticosteroid treatment. One year later, both eyes were involved. Examination of the vitreous aspirate and the results of a chorioretinal biopsy OD did not yield a correct diagnosis. Computed tomographic scanning showed orbital invasion OD. Malignant lymphoma was diagnosed after a biopsy specimen of the orbital contents was studied histopathologically. Radiotherapy and chemotherapy diminished the orbital mass and intraocular lesions. After regression of the orbital lesion, a brain tumor was found and treated with radiotherapy and chemotherapy. At age 57 years, the patient died. We believe that our patient had a rare case of intraocular lymphoma associated with orbital invasion.

Cranial Nerve Neoplasms↗
PubMed1993

Occlusion therapy of Japanese children with anisometropic amblyopia without strabismus.

We examined 38 children (20 boys and 18 girls) with anisometropic amblyopia without strabismus who had been treated with occlusion therapy. At the initial visit, their ages ranged from five to ten years. Their visual acuity scores improved after therapy, and this was unrelated to patient age. The amount of anisometropia, visual acuity at the initial visit, and compliance were related to improved visual acuity in the amblyopic eye. The visual acuity improved for six months after therapy. No further gains were detected thereafter.

Amblyopia↗
PubMed1993

Central retinal vein occlusion in two patients with immunoglobulin G multiple myeloma associated with blood hyperviscosity.

A 69-year-old man (Patient 1) complained of anorexia, lumbago, and seeing floaters OS. The results of laboratory tests showed immunoglobulin (Ig) G lambda-type multiple myeloma associated with blood hyperviscosity. Retinal hemorrhages OD and central retinal vein occlusion OS were found. A 71-year-old woman (Patient 2) with IgG kappa-type multiple myeloma had blood hyperviscosity. Retinal microaneurysms OD and central retinal vein occlusion OS were found. We believe that our patients represent rare cases of IgG multiple myeloma associated with blood hyperviscosity and central retinal vein occlusion.

Aged↗
PubMed1992

Conformational changes of actin induced by calponin.

Calponin, an actin-linked regulatory protein in smooth muscle, caused a remarkable change in the fluorescence intensity of pyrene-labeled actin in the filamentous form. Calponin, an equimolar ratio to actin, decreased the fluorescence intensity of pyrene-labeled F-actin by some 60% to the level near monomeric actin. This change was partially reversed by Ca2+, when calmodulin was present. Thus it appears that calponin causes conformational changes in actin molecules in an actin filament so as to inhibit their interactions with myosin.

Actins↗
PubMed1992

Posterior chamber intraocular lens implantation in a patient with oculocutaneous albinism.

A 56-year-old woman with tyrosinase-negative oculocutaneous albinism complained of gradually decreasing vision in the left eye. Her visual acuity was 20/300 in the right eye and hand motion in the left eye. She had pink skin and white hair and cilia. On examination, bilateral hypopigmented irides, an opaque lens in the left eye, a hypopigmented fundus in the right eye, and nystagmus were found. An extra-capsular cataract extraction with posterior chamber intraocular lens (IOL) implantation was performed. After retrobulbar anesthesia was administered, the nystagmus ceased temporarily. Postoperatively, visual acuity in the left eye improved to 20/200. We believe IOL implantation is useful in the treatment of cataracts in albino patients.

Albinism, Oculocutaneous↗
PubMed1992

Waardenburg syndrome in Japanese patients. Case reports and literature review.

A 3-year-old girl (case 1) had a blue iris and albinotic fundus in the right eye and bilateral deafness. Her 6-month-old sister (case 2) had hypopigmented irides and fundi in both eyes and bilateral deafness. We found that the ratios of interinner canthal distance to interpupillary distance were less than 0.65 in normal Japanese controls. In our patients, these ratios were within the normal range, indicating the absence of dystopia canthorum. After reviewing the recent Japanese literature, we found that the hypopigmented iris and deafness seen in our patients are common in Japanese patients with Waardenburg syndrome.

Adult↗
PubMed1992

Giant meningioma fed by the anterior choroidal artery: successful removal following embolization--case report.

A 53-year-old female was admitted with apathy, left sensory and motor disturbance, left homonymous hemianopsia, and dressing apraxia. Computed tomography and magnetic resonance imaging showed a huge mass markedly enhanced in and around the right trigone. Cerebral angiography revealed rich vascularity of the tumor mainly fed by the right anterior choroidal artery. The feeding vessel was embolized with microfibrillar collagen after superselective catheterization. Seven days later, the tumor was totally removed with low blood loss. The histological diagnosis was fibroblastic meningioma. She was discharged without neurological deficit, except for left homonymous hemianopsia.

Arteries↗
PubMed1992

Leber congenital amaurosis in an infant with Down syndrome.

A male infant had defects of atrial and ventricular septa and trisomy 21. At 2 months of age, the patient had markedly sluggish pupillary reactions to light OU. Searching nystagmus, multiple chorioretinal atrophic spots in mottled retinas, and unrecordable electroretinograms also were found in the patient when he was 6 months of age. We believe that this infant represents a rare case of Leber congenital amaurosis in association with Down syndrome.

Atrophy↗
PubMed1992

Radiotherapy resolves leukemic involvement of the optic nerves.

A 40-year-old woman with acute lymphoblastic leukemia had a visual disturbance OD. The optic disc was slightly swollen in the right fundus, and blast cells in the cerebrospinal fluid were found. Radiotherapy to the brain and orbit resolved these findings. Five months later, visual acuity decreased OS. Radiotherapy also was effective in treating the leukemic involvement of the optic nerve.

Adult↗
PubMed1992

Optic nerve glioma in Japanese patients with neurofibromatosis 1. Case reports and literature review.

Case 1, a 6-year-old boy, had multiple café-au-lait spots, no light perception OS, Lisch nodules OU, pale optic disc OS, enlarged left optic nerve on computed tomographic scan and magnetic resonance imaging, and histopathologically verified pilocytic astrocytoma (glioma). The patient's mother had neurofibromatosis 1 (NF-1). Case 2, a 12-year-old boy, had multiple café-au-lait spots, decreased visual acuity OU, Lisch nodules OU, pale optic discs OU, enlarged optic nerves and chiasm on computed tomographic scan, and histopathologically verified pilocytic astrocytoma. We also examined 38 Japanese patients with NF-1 and found Lisch nodules in 95% and optic nerve glioma in 5%. After reviewing the recent literature, we found that the association of optic nerve glioma and NF-1 in the Japanese population was less than that reported in North America.

Adolescent↗
PubMed1992

Effects of excretory-secretory products of Echinostoma paraensei larvae on the hematopoietic organ of M-line Biomphalaria glabrata snails.

Responses of the hematopoietic organ (HO) in Biomphalaria glabrata snails to extracts and excretory-secretory (E-S) products of Echinostoma paraensei larvae were studied to understand the HO-activating mechanism. M-line B. glabrata snails were injected with materials from E. paraensei larvae, and the size of the HO was ascertained in histological sections. The size of HO in snails injected with extracts and E-S products from sporocysts and rediae was significantly larger than that in snails injected with culture medium. E-S products of sporocysts were fractionated using ultrafiltration membranes, polyacrylamide gel electrophoresis, and electrophoretic elution. Examination of fractionated E-S products of sporocysts revealed that specific components of E-S products were responsible for HO-stimulating activity.

Animals↗