Studies on regulation of fatty acid synthesis by thyroid hormone.
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Biomedical subjects
Publications and source records attributed to S Mukherjee.
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Fish under abnormal environmental conditions suffer from retarded growth and other physiological dysfunctions related to thyroxine deficiency. In teleosts lacking a definite thyroid gland the kidney plays a very important role in biosynthesis of the thyroidal hormone, in which peroxidase has an indirect action. Effects of some industrial pollutants and factory effluents on fish kidney peroxidase activity were recorded in Ophicephalus punctatus and Clarias batrachus. At concentrations of the pollutants at which 70-100% of the fish survive the exposure, peroxidase activity was greatly inhibited, indicating that even sub-lethal doses of toxicants may cause drastic changes in the physiological systems. The peroxidase activity increased well above the control levels at 5-h and 27-h exposures in some cases, but declined towards the end of the test.
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The procedure used to determine the pionnucleon coupling constant g(2) from multi-energy fits to nucleon-nucleon (N-N) scattering data has been shortened without a material loss of accuracy. The g(2) presetting effect is discussed in connection with the limited accuracy of g(2) determinations in general and the possibilities of the "optimized polynomial expansions". The desirability of the Yale graded introduction of one-pion exchange (OPE)-to-"searched" transition energies (E(tr)) is brought out. Corrections for virtual discontinuities in phase-shift-energy dependence at the E(tr) decreased the violation of long-range charge independence (LRCI). The effect of two-pion exchange (TPE) has been calculated on the ps theory as approximately 1 for go(2)(p-p) - go(2)(n-p), go(2) = g(2)/[unk]c; a result consistent with LRCI. Searching all phase parameters including g(2) for both isospin values I in g(2) determinations from n-p data, but with fixed I = 1 non-OPE phases as deduced from p-p data in the base search with frozen g(2), the OPE effect of the neutral pion, pi degrees , was separated from that of the charged pion, pi(c). The g(2) for pi(c) in n-p scattering is determined with much better statistical accuracy than that for pi degrees . The overall n-p value of g(2) is nearly equal to that for pi(c). The results suggest that the distinction between p-p and n-p values of g(2), if present, is in first approximation that arising from the difference between pi degrees -N and pi(c)-N couplings. Some limitations on the validity of the conclusions are mentioned.
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