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Biomedical subjects

S M Ali

Publications and source records attributed to S M Ali.

At least 145 records · Page 8Linked to original sources
PubMed1983

Peroral endoscopic duodenal biopsy in infants and children.

Peroral endoscopic duodenal biopsy was used in the diagnosis and follow-up of forty-nine infants and children with suspected small intestine disease. Their ages ranged between one month and 12 years. Fifty-four upper gastrointestinal endoscopy procedures were performed and 139 biopsies were taken. The mean procedure time was 3.2 min with a range of 1.5-5.5 min. There were no complications. Tissue adequate for histopathologic examination was obtained in all but one of the fifty-four procedures. On the basis of this experience we think that peroral endoscopic duodenal biopsy is faster, safer and as diagnostic as conventional suction biopsy in infants and children. It is also more informative when other diseases of the upper gastrointestinal tract are suspected.

Biopsy↗
PubMed1982

Dasherkandi project studies--health of the under fifteen.

Morbidity pattern of the under fifteen of a rural community was analysed and related to socio-economic factors. This was a part of Dasherkandi project studies carried out in a village near Dhaka city. 48.26% of the population was under the age of fifteen. Infants under the age of one year had low sickness rate which rose steeply between 1 and 4 years of life and then gradually declined after the age of 5 years. Commonest morbidity was worm infestation which was followed by flu and upper respiratory tract infection. The non-agriculturist and the low income group had the highest level of sickness. It is suggested that children in rural areas suffer mainly from diseases which are related to poor nutrition and hygiene resulting from unsatisfactory socio-economic condition. All the childhood mortality occurred under the age of one year and was found to be due to tetanus in this study.

Adolescent↗
PubMed1981

Dasherkandi project studies. Demography, morbidity and mortality in a rural community of Bangladesh.

The entire population of Dasherkandi, a village near Dacca city was surveyed. Out of 1181 people 44.2% suffered from organic or psychiatric disorders. 37.7% suffered from physical disorders, 3.6% suffered from psychiatric disorders and another 2.9% suffered from both psychiatric and physical disorders. The common physical disorders were worm infestations, hypertension, peptic ulcer, dental problems and upper respiratory tract infection including flu. Females suffered from psychiatric diseases more than males. The psychiatric morbidity found in the survey differed significantly from those found in other similar surveys. Depressive states were the commonest psychiatric disorder and women suffered four times as frequently as men. Anxiety neurosis was the next common psychiatric problem. Both crude mortality and infant mortality rates (5.75 and 93.20 per thousand respectively) were lower than those of other similar studies. The commonest cause of infant mortality during first one month of life was tetanus in this series. Inspite of the fact that diagnosis was based entirely on clinical findings the morbidity rate was high. It was observed that a high percentage of the people who suffered from psychiatric disorders were due to problems which can be easily tackled under field conditions.

Adolescent↗
PubMedDate not supplied

Congenital benign mesenchymoma of the head and neck.

Congenital benign mesenchymoma of the head and neck is rare. One such case, presenting as a mass in the neck, is reported and the literature reviewed. Pathologic nature of the lesion is discussed. Prognosis after adequate local excision is good.

Head and Neck Neoplasms↗
PubMedDate not supplied

Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice.

In an attempt to generate transgenic mice modeling Alzheimer-type amyloidogenesis, the COOH-terminal 103 residue human APP segment was expressed in brain regions known to be vulnerable in AD. Transfected cells overexpressing this transgene were previously shown to develop intracytoplasmic inclusions that were immunoreactive with antibodies to the APP COOH-terminus. Transgenic C57B6/SJL mice produced transgene-coded mRNA in their brains at levels up to sixfold above endogenous APP, most abundantly within cortical and hippocampal pyramidal neurons. Immunocytochemistry with anti-A beta antibodies revealed occasional structures that resembled diffuse amyloid, but which could not be detected on serial sections. Immunolabeling with antibodies to APP regions NH2-terminal to the transgene-coded domain revealed elevated immunoreactivity within perikarya and neurites in regions expressing the highest transgene and endogenous APP mRNA levels, similar to observations previously reported within vulnerable neurons in AD brain. However, subsequent breeding revealed that this phenotype segregated with the B6/SJL background rather than the transgene, thus emphasizing the importance of genetic background to observations of putative AD-type pathology in transgenic animals.

Alzheimer Disease↗