Biomedical subjects

S Lehrl

Publications and source records attributed to S Lehrl.

75 records · Page 5Linked to original sources

PubMedDate not supplied

Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study).

A three-armed, randomized, multicentre, placebo-controlled double-blind study was used to examine the efficacy of benfotiamine vs a combination containing benfotiamine and vitamins B6 and B12 in out-patients with severe symptoms of alcoholic polyneuropathy (Benfotiamine in treatment of Alcoholic Polyneuropathy, BAP I). The study period was 8 weeks and 84 patients fulfilled all the prerequisite criteria and completed the study as planned. Benfotiamine led to significant improvement of alcoholic polyneuropathy. Vibration perception (measured at the tip of the great toe) significantly improved in the course of the study, as did motor function. and the overall score reflecting the entire range of symptoms of alcoholic polyneuropathy. A tendency toward improvement was evident for pain and co-ordination; no therapy-specific adverse effects were seen.

Adult↗

PubMedDate not supplied

[Cerebrovascular insufficiency and compliance with drug therapy].

Particularly elder multimorbid patients suffering from a cerebrovascular insufficiency need a long term therapy. One condition for success, however, is the regular intake of drugs by the patient. Therefore the final goal is the increase of drug-compliance. This is based on the enhancement of the knowledge of the actual drug-compliance, the subject we wanted to learn more about by empirical investigations. During one year the drug-compliance of each patient of the Special Clinic Klausenbach was tested over a period of 20 days. The results were taken by checking riboflavin fluorometrically (method according to Gundert-Remy). In this way the patients could be classified as "takers" and "non-takers". The following variables wee considered: diagnoses, marital status, age, nationality, profession, IQ, mood, subjective evaluation of success of cure and medication. since according to a pre-study foreigners show a lower rate of compliance we restricted the sample to the 892 german cure patients, 343 of whom suffered from cerebrovascular diseases. Their compliance-level was almost 50%. The results of the subgroups hardly differed. The cure patients suffering from cerebrovascular insufficiencies did not show any striking compliance behaviour: the values are far below the ideal value, however. Further multivariate statistical analyses are designed to contribute to the development of effective measures of intervention.

Aged↗

PubMedDate not supplied

[Psychological findings in a group of patients with perioral dermatitis].

Female patients suffering from perioral dermatitis were given the Raven Test, two personality inventories (MMPI and FPI) and the Rorschach Test. The results of these four tests show statistically significant differences from controls, indicating emotional immaturity combined with high intelligence level, inability to achieve satisfactory interpersonal relationships contrasting with an overemphasis upon social conformity, and a tendency to 'hysteriform' reactions.

Dermatitis↗