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Biomedical subjects

S Langer

Publications and source records attributed to S Langer.

At least 91 records · Page 5Linked to original sources
PubMed1977

[Modification of immunoglobulins during combined peroral and parenteral nutrition in colitis, ileitis and rectal carcinoma].

Reaction of immunoglobulins (IgA, IgG, IgM) during a four week period under condition with a special parenteral and peroral alimentation was observed in three groups of patients (rectum neoplasm, ulcerative colitis, Crohn's disease) during a period of two weeks all patients received 150 g aminoacids and 510 g carbohydrates by central venous catheter. In the following 14 days parenteral nutrition was limited and oral alimentation began. All patients showed a remarkable approvment of recreation. Globulins rose in between normal spectrum. The most marked changes with a significant uprising of IgG showed patients with rectum carcinoma treated cryosurgically.

Colitis, Ulcerative↗
PubMed1976

[Healing process of colonic anastomosis after contamination with Staphylococcus aureus (author's transl)].

In 30 rats the healing process of colonic anastomosis contaminated with Staphylococcus aureus was studied. At the same time on each animals a single- and double-layer anastomosis was performed. All sutures were infected during the surgical procedure with highly infectious S. aureus. The rats were sacrificed after 1, 2, 3, 4 days, and 2 1/2 weeks. Criteria for estimation were mainly visible abscess formations, leakage spots, bacteriologic and histologic examinations. After apparent inflammatory reactions were seen on the first postoperative days with a maximum on the 4th day, all sutures were completely healed and free of S. aureus after 2 1/2 weeks. As for the extent of infectious inflammation, the single-layer suture technique proved to be more resistant than the double layer.

Animals↗
PubMed1976

[Dietetic and antibiotic preparation in surgery of the large intestine].

Besides patient's cardiac, pulmonary, renal and hepatic status, a correct operative technique and mechanical bowel cleansing the protein status is of central importance to prevent anastomotic leakage and wound infection in colon surgery. Using an oral elemental diet prior to surgery both sufficient caloric and protein intake and reduction of intestinal flora can be achieved. Wound infection and anastomotic leakage are reduced significantly without the side effects of antibiotic bowel preparation. If oral antibiotics are used preoperatively only a short term low dose regimen is effective for the control of infection after colon surgery which reduces the concentration of aerobes and anaerobes.

Anti-Bacterial Agents↗
PubMed1975

[Local cryosurgical management of colonic and rectal cancer].

Complex experimental investigations created the basis for cryosurgical treatment of colon and rectum cancer. 27 patients were chosen for cryotherapy according to strict indication. Especially developed instruments and technique are presented. A three year-follow up-study shows 19 patients alive, most of them without recurrence or troubles. Immediately after starting with cryosurgical treatment patients recover remarkably. In collaboration with the Dept. of Microbiology (Rhein.-Westfäl. Techn. Hochschule Aachen) the possibility of a special cryoimmunological response is investigated.

Adult↗
PubMedDate not supplied

[Outbreak of infection with methicillin-resistant Staphylococcus aureus (MRSA) in an orthopedic septic care unit--measures for eradication and subsequent colonization studies].

An outbreak due to a methicillin-resistant S. aureus (MRSA) strain in an orthopaedic septic care unit was observed. 17 patients developed wound infections. Stronger regime of hygiene and chemotherapy and new technics of operations controlled the outbreak within 5 months. Studies of colonisation were performed at the care unit in march, june and august 1992. 618 isolates were investigated from patients, personnel and their environment. The frequencies of detected MRSA diminished from 30% in march only to 22% in august 1992. The long time persistence of endemic MRSA in a care facility was evident from the presence of MRSA even 5 months after the last infection.

Aged↗