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Biomedical subjects

S L Waller

Publications and source records attributed to S L Waller.

At least 37 records · Page 2Linked to original sources
PubMed1972

Effect of eating on motility of the pelvic colon in constipation or diarrhoea.

Pelvic colonic pressures were recorded before, during, as well as after a meal in patients with non-specific diarrhoea (12) or constipation (14), who were selected according to strict clinical criteria of bowel habit. In the basal state diarrhoeal patients as a group had significantly less colonic activity than constipated patients, but the overlap was considerable. During the meal colonic activity was strikingly increased in diarrhoea, but returned to basal levels immediately after the meal; no such response was observed in constipation. It is suggested that this brief segmental response of the pelvic diarrhoeal colon may be inadequate to prevent entry of faeces into the rectum and the desire to defaecate, following a meal.

Adult↗
PubMed1971

The hourly rate of urinary amylase excretion, serum amylase, and serum lipase. I. In control subjects and patients with renal disease.

The rates of urinary amylase excretion/hour and the levels of serum amylase and lipase were measured in 190 normal subjects and patients with no evidence of renal or gastrointestinal disorder. The hourly rate of urinary amylase excretion/hour was found to have an upper limit of normal of 69 IU. The upper limit of normal for the serum amylase was 251 IU/litre and for the serum lipase 1.6 units/ml. Raised levels of serum amylase and lipase with a normal rate of urinary amylase excretion/hour were found in chronic renal failure.

Adolescent↗
PubMed1971

The hourly rate of urinary amylase excretion, serum amylase, and serum lipase. II. Patients with gastrointestinal and pancreatic disorders.

Gastrointestinal disease other than hepatobiliary and pancreatic disorders was associated with hourly rates of urinary amylase excretion above the limits of normal for control subjects (88 IU/hour compared with 69 IU/hour). In hepatobiliary disease, excretion rates of more than 88 but usually less than 190 IU/hour were sometimes found. Whilst rates of urinary amylase excretion were not helpful in the diagnosis of chronic pancreatitis or carcinoma of the pancreas, levels above 190 IU/hour were found in acute pancreatitis at a time when the serum levels were also diagnostic. After the acute episode the rate of urinary amylase excretion was moderately elevated for up to six days but did not reach diagnostic levels. Persistent elevation of serum amylase and lipase levels and hourly rates of urinary amylase excretion for more than six days suggested that a pseudocyst had developed. In acute pancreatitis the level of serum lipase was more frequently raised and persisted so for longer than either the serum or urinary amylase. Although the hourly rate of urinary amylase excretion is of little value alone, when performed in conjunction with evaluating the serum amylase and lipase it may provide useful additional evidence of pancreatic disease and it could be useful in the diagnosis of relapsing chronic pancreatitis.

Acute Disease↗
PubMed1969

Gastrointestinal motility and gastric secretion during intravenous infusions of gastrin II.

The effect of intravenous infusion of gastrin II on gastric and colonic motor activity was studied in 12 patients; gastric acid output was also measured. Administration of gastrin at near-maximal dose levels stimulates the motor activity of the antrum but has no measurable effect on the activity of the proximal colon, sigmoid, or rectum. The results suggest that gastrin plays a part in the regulation of gastric motility but that it is not a mediator of the gastro-colic reflex.

Colon↗