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Biomedical subjects

S L Fischman

Publications and source records attributed to S L Fischman.

At least 37 records · Page 2Linked to original sources
PubMed1985

The use of medical and dental radiographs in identification.

Following mass disasters and individual deaths, dentists with special training and experience in forensic odontology are frequently called upon to assist in the identification of badly mutilated or decomposed bodies. Teeth and dental restorations are resistant to destruction by fire and the elements and are, therefore, useful in identification. The forensic odontologist makes use of dental radiographs taken of the victim before death. These are compared to dental data from the remains to assist in making the identification. Many features of the teeth and numerous characteristics of dental treatment are quite unique. This permits accurate and legally acceptable identification of the remains. The cases described illustrate the procedures and techniques of identification using ante-mortem and post-mortem radiographs.

Adult↗
PubMed1983

The patient with cancer.

Patients with cancer require competent oral health care, provided by a sympathetic and conscientious clinician. Often the ambulatory patient will be best managed by the generalist-family dentist. An understanding of the nature of oral disease in these compromised patients and a readiness to discuss dental treatment modifications with the attending physician should help prepare the dentist to prevent and to treat oral disease in the patient with cancer.

Dental Care for Persons with Disabilities↗
PubMed1982

Correlative clinico-pathological evaluation of oral premalignancy.

In 1972, the World Health Organization's "Meeting of Investigators on the Histological Definitions in Precancerous Lesions" defined a precancerous lesion as a "morphologically altered tissue in which cancer is more likely to occur than in its apparently normal counter part" (Pindborg 1980). There are two generally accepted precancerous lesions in the oral cavity, leukoplakia and erythroplakia (Pindborg 1980). Leukoplakia is currently defined as "a white patch or plaque that cannot be characterized clinically or pathologically as any other disease" (WHO 1978). This definition has no histological connotation and is used in a strictly clinical sense (Pindborg 1980, Banoczy 1977). Erythroplakia is defined as a "bright red velvety plaque which cannot be characterized clinically or pathologically as being due to any other condition" (Pindborg 1980).

Diagnosis, Differential↗
PubMed1979

Inter-examiner reliability in caries trials.

A statistical model is given for representing the several components of variability present in measurements (e.g., DMFS scores) given by examiners to patients. Methods for making inferences about the intraclass correlation coefficient of reliability are presented and illustrated on a real set of data. The proper analysis of data from a reliability study is shown to depend on the planned design and analysis of the clinical or field trial to be conducted following the reliability trial.

Child↗
PubMed1979

Design of studies to evaluate plaque control agents.

The importance of plaque in the etiology of periodontal diseases is reviewed. A survey is also presented of the various indices for scoring plaque in clinical trials. Variations in the clinical design, type of population studied, and difficulty in scoring gingival plaque are reviewed. A survey is presented of some recent published studies of plaque-inhibiting agents.

Anti-Bacterial Agents↗
PubMed1978

In vitro antiplaque properties of a series of alkyl bis(biguanides).

A series of eight alkyl bis(biguanide) analogues of alexidine, N,N''''-1,6-hexanediyl bis[N'-(2-ethylhexyl)imidodicarbonimidic diamide] (1), was prepared. Five of these analogues constituted a series isolipophilic with 1 but with varying bridge length between biguanide moieties. The compounds were evaluated in vitro for antibacterial and antiplaque properties against Streptococcus mutans, Actinomyces viscosus, and Actinomyces naesludii. One analogue, N N,''''-1,6-hexanediyl bis[N'(n-octyl)imidodicarbonimidic diamide], appeared to be more effective than either 1 or chlorhexidine against this spectrum of dental plaque forming microorganisms.

Actinomyces↗
PubMed1978

Randomized, double-blind study of levamisole in recurrent aphthous stomatitis.

A randomized double-blind study was designed to evaluate the safety and efficacy of levamisole in the treatment of recurrent aphthous stomatitis (RAS). Thirty patients, aged 9-65 years, were selected, based on a documented history of three or more episodes of RAS. Patients were instructed to take 150 mg of levamisole (or placebo) daily for 3 days at the onset of the first prodromal symptoms of an ulcer. The regimen was to be repeated for each new episode, but not more than once per week. At each episode patients were examined and evaluated as to number and duration of ulcers, interval between episodes, pain associated with ulcers, and side effects. Data on 24 patients were suitable for analysis. Of those patients receiving levamisole, six showed slight improvement and five were unchanged. Of those patients receiving the placebo, one showed a marked improvement, four slight improvement, six were unchanged, and two deteriorated. There was neither a clinical nor a statistically significant difference between the groups. It is concluded that levamisole, in this study protocol, had no effect on the incidence or severity of aphthous ulcers.

Adolescent↗
PubMed1977

Oral cancer in Puerto Rico.

All cancer cases diagnosed in Puerto Rico are analyzed and registered in the Central Cancer Registry. The incidence of oral cancer in Puerto Rico is fourth-highest in the world. (In 1972 oral cancer accounted 72% of all cancers in males in Puerto Rico.) A review of the data revealed important contrasts with reported statistics from the continental United States (e.g., 75.6% of the cases in Puerto Rico were initially treated by radiation, compared with 15.3% of the cases in Western New York States.

Age Factors↗
PubMed1977

Histopathologic, ultrastructural, and immunologic findings in an oral psoriatic lesion.

There has been some controversy over whether psoriasis can involve the oral mucosa. An oral lesion in a 32-year-old man with a psoriatic scalp lesion has been studied by light and electron microscopy and by immunologic methods. Results from each of these three techniques are consistent with previous findings in psoriatic lesions and suggest that oral psoriasis can occur.

Adult↗
PubMed1977

In vitro antiplaque effects of antiseptic phenols.

Several phenols known to be antiseptics were tested in vitro for their ability to adsorb to saliva-coated enamel and subsequently inhibit plaque formation. 3,5,4'-tribromosalicylanilide was found to be effective against growth and plaque formation of A viscosus, A naeslundii, S mutans and S sanguis. Dibromsalicil was effective against A viscosus. The other phenols (hexylresorcinol, thymol, phenylphenol and zinc phenolsulfonate) did not inhibit in vitro growth or plaque formation.

Animals↗